HUP0202042A2 - Inzulin alkalmazása cukorbetegek éhgyomori vércukrának és testsúlynövekedésének csökkentésére szolgáló gyógyszerkészítmény előállítására - Google Patents
Inzulin alkalmazása cukorbetegek éhgyomori vércukrának és testsúlynövekedésének csökkentésére szolgáló gyógyszerkészítmény előállításáraInfo
- Publication number
- HUP0202042A2 HUP0202042A2 HU0202042A HUP0202042A HUP0202042A2 HU P0202042 A2 HUP0202042 A2 HU P0202042A2 HU 0202042 A HU0202042 A HU 0202042A HU P0202042 A HUP0202042 A HU P0202042A HU P0202042 A2 HUP0202042 A2 HU P0202042A2
- Authority
- HU
- Hungary
- Prior art keywords
- insulin
- preparing
- pharmaceutical composition
- diabetic patients
- weight gains
- Prior art date
Links
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 title 2
- 102000004877 Insulin Human genes 0.000 title 1
- 108090001061 Insulin Proteins 0.000 title 1
- 208000021017 Weight Gain Diseases 0.000 title 1
- 230000003247 decreasing effect Effects 0.000 title 1
- 206010012601 diabetes mellitus Diseases 0.000 title 1
- 229940125396 insulin Drugs 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 235000000346 sugar Nutrition 0.000 title 1
- 150000008163 sugars Chemical class 0.000 title 1
- 230000004584 weight gain Effects 0.000 title 1
- 235000019786 weight gain Nutrition 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Diabetes (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Endocrinology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Otolaryngology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Pulmonology (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US30004901P | 2001-06-21 | 2001-06-21 |
Publications (3)
Publication Number | Publication Date |
---|---|
HU0202042D0 HU0202042D0 (hu) | 2002-08-28 |
HUP0202042A2 true HUP0202042A2 (hu) | 2004-05-28 |
HUP0202042A3 HUP0202042A3 (en) | 2004-06-28 |
Family
ID=23157477
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0202042A HUP0202042A3 (en) | 2001-06-21 | 2002-06-20 | Use of insulin for preparing of pharmaceutical composition for decreasing fasting sugars and weight gains in diabetic patients |
Country Status (15)
Country | Link |
---|---|
US (2) | US20030079747A1 (hu) |
EP (1) | EP1270012A1 (hu) |
JP (1) | JP2003012543A (hu) |
KR (1) | KR20020097033A (hu) |
CN (1) | CN1289143C (hu) |
AU (1) | AU4884102A (hu) |
CA (1) | CA2390757A1 (hu) |
CZ (1) | CZ20022151A3 (hu) |
HK (1) | HK1049617B (hu) |
HU (1) | HUP0202042A3 (hu) |
IL (1) | IL150209A0 (hu) |
NZ (1) | NZ519403A (hu) |
PL (1) | PL354641A1 (hu) |
SK (1) | SK9042002A3 (hu) |
ZA (1) | ZA200204859B (hu) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004054606A1 (en) * | 2002-12-13 | 2004-07-01 | Pfizer Products Inc. | Method of decreasing hepatic glucose output in diabetic patients |
WO2004078196A1 (en) * | 2003-03-04 | 2004-09-16 | The Technology Development Company Ltd. | Oral insulin composition and methods of making and using thereof |
JP2009519972A (ja) * | 2005-12-15 | 2009-05-21 | アキュスフィア, インコーポレイテッド | 粒子ベースの経肺投与または経鼻投与用製薬の製造方法 |
WO2008118387A2 (en) * | 2007-03-23 | 2008-10-02 | Wayne State University | Erythrocyte atp-release modulators |
EP2060268A1 (en) * | 2007-11-15 | 2009-05-20 | Novo Nordisk A/S | Pharmaceutical compositions for pulmonary or nasal delivery of peptides |
JP5650734B2 (ja) * | 2009-07-22 | 2015-01-07 | イーライ リリー アンド カンパニー | 薬物療法に関連する体重増加を予測するための方法 |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5230884A (en) * | 1990-09-11 | 1993-07-27 | University Of Wales College Of Cardiff | Aerosol formulations including proteins and peptides solubilized in reverse micelles and process for making the aerosol formulations |
DK10191D0 (da) * | 1991-01-22 | 1991-01-22 | Novo Nordisk As | Hidtil ukendte peptider |
DE69233690T2 (de) * | 1991-07-02 | 2008-01-24 | Nektar Therapeutics, San Carlos | Abgabevorrichtung für nebelförmige Medikamente |
US5320094A (en) * | 1992-01-10 | 1994-06-14 | The Johns Hopkins University | Method of administering insulin |
US5785049A (en) * | 1994-09-21 | 1998-07-28 | Inhale Therapeutic Systems | Method and apparatus for dispersion of dry powder medicaments |
US6582728B1 (en) * | 1992-07-08 | 2003-06-24 | Inhale Therapeutic Systems, Inc. | Spray drying of macromolecules to produce inhaleable dry powders |
US6024090A (en) * | 1993-01-29 | 2000-02-15 | Aradigm Corporation | Method of treating a diabetic patient by aerosolized administration of insulin lispro |
US5743250A (en) * | 1993-01-29 | 1998-04-28 | Aradigm Corporation | Insulin delivery enhanced by coached breathing |
US6051256A (en) * | 1994-03-07 | 2000-04-18 | Inhale Therapeutic Systems | Dispersible macromolecule compositions and methods for their preparation and use |
KR100419037B1 (ko) * | 1994-03-07 | 2004-06-12 | 넥타르 테라퓨틱스 | 폐를통한인슐린의전달방법및그조성물 |
CN1131080C (zh) * | 1994-09-21 | 2003-12-17 | 吸入治疗系统 | 用于喷洒干的粉末药物的方法和装置 |
US5898028A (en) * | 1997-03-20 | 1999-04-27 | Novo Nordisk A/S | Method for producing powder formulation comprising an insulin |
DE19733651A1 (de) * | 1997-08-04 | 1999-02-18 | Boehringer Ingelheim Pharma | Wässrige Aerosolzubereitungen enthaltend biologisch aktive Markomoleküle und Verfahren zur Erzeugung entsprechender Aerosole |
DE69920767T2 (de) * | 1998-10-16 | 2006-02-02 | Novo Nordisk A/S | Stabile konzentrierte Insulin Präparationen zur pulmonaren Verabreichung |
EP1173482A1 (en) * | 1999-04-27 | 2002-01-23 | Eli Lilly And Company | Insulin crystals for pulmonary administration |
AU5453300A (en) * | 1999-06-29 | 2001-01-31 | Eli Lilly And Company | Insulin crystals for pulmonary administration |
US7060675B2 (en) * | 2001-02-15 | 2006-06-13 | Nobex Corporation | Methods of treating diabetes mellitus |
US6838442B2 (en) * | 2001-04-04 | 2005-01-04 | Ortho-Mcneil Pharmaceutical, Inc. | Combination therapy comprising glucose reabsorption inhibitors and retinoid-X receptor modulators |
AU2002303869B2 (en) * | 2001-05-21 | 2007-08-16 | Novartis Ag | Pulmonary administration of chemically modified insulin |
-
2002
- 2002-06-06 NZ NZ519403A patent/NZ519403A/en unknown
- 2002-06-06 EP EP02253950A patent/EP1270012A1/en not_active Ceased
- 2002-06-12 IL IL15020902A patent/IL150209A0/xx unknown
- 2002-06-17 CA CA002390757A patent/CA2390757A1/en not_active Abandoned
- 2002-06-18 ZA ZA200204859A patent/ZA200204859B/xx unknown
- 2002-06-19 US US10/176,146 patent/US20030079747A1/en not_active Abandoned
- 2002-06-19 AU AU48841/02A patent/AU4884102A/en not_active Abandoned
- 2002-06-19 CZ CZ20022151A patent/CZ20022151A3/cs unknown
- 2002-06-20 HU HU0202042A patent/HUP0202042A3/hu unknown
- 2002-06-20 PL PL02354641A patent/PL354641A1/xx not_active Application Discontinuation
- 2002-06-20 JP JP2002179903A patent/JP2003012543A/ja not_active Revoked
- 2002-06-21 CN CNB02124880XA patent/CN1289143C/zh not_active Expired - Fee Related
- 2002-06-21 KR KR1020020034812A patent/KR20020097033A/ko not_active Application Discontinuation
- 2002-06-21 SK SK904-2002A patent/SK9042002A3/sk unknown
-
2003
- 2003-03-08 HK HK03101700.6A patent/HK1049617B/zh not_active IP Right Cessation
-
2005
- 2005-05-27 US US11/140,052 patent/US20050220722A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1270012A1 (en) | 2003-01-02 |
HUP0202042A3 (en) | 2004-06-28 |
AU4884102A (en) | 2003-01-02 |
PL354641A1 (en) | 2002-12-30 |
CN1289143C (zh) | 2006-12-13 |
CN1393265A (zh) | 2003-01-29 |
CZ20022151A3 (cs) | 2003-04-16 |
ZA200204859B (en) | 2004-01-28 |
KR20020097033A (ko) | 2002-12-31 |
NZ519403A (en) | 2005-03-24 |
HU0202042D0 (hu) | 2002-08-28 |
US20050220722A1 (en) | 2005-10-06 |
CA2390757A1 (en) | 2002-12-21 |
HK1049617B (zh) | 2007-03-16 |
US20030079747A1 (en) | 2003-05-01 |
JP2003012543A (ja) | 2003-01-15 |
SK9042002A3 (en) | 2003-05-02 |
HK1049617A1 (en) | 2003-05-23 |
IL150209A0 (en) | 2002-12-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD9A | Lapse of provisional protection due to non-payment of fees |