HUP0201181A2 - 1,5-Benzodiazepin-származék előállítása és az ezt tartalmazó gyógyszerkészítmény - Google Patents
1,5-Benzodiazepin-származék előállítása és az ezt tartalmazó gyógyszerkészítményInfo
- Publication number
- HUP0201181A2 HUP0201181A2 HU0201181A HUP0201181A HUP0201181A2 HU P0201181 A2 HUP0201181 A2 HU P0201181A2 HU 0201181 A HU0201181 A HU 0201181A HU P0201181 A HUP0201181 A HU P0201181A HU P0201181 A2 HUP0201181 A2 HU P0201181A2
- Authority
- HU
- Hungary
- Prior art keywords
- producing
- pharmaceutical composition
- composition containing
- benzodiazepine derivatives
- rich
- Prior art date
Links
- ZVAPWJGRRUHKGP-UHFFFAOYSA-N 1h-1,5-benzodiazepine Chemical class N1C=CC=NC2=CC=CC=C12 ZVAPWJGRRUHKGP-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
- 239000005711 Benzoic acid Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/12—1,5-Benzodiazepines; Hydrogenated 1,5-benzodiazepines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Gastroenterology & Hepatology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
A találmány tárgya enantiomer dús 3-{3-[1-(N-izopropil-N-fenil-karbamoilmetil)-2,4-dioxo-5-fenil-2,3,4,5-tetrahidro-1H-benzo[b][1,4]diazepin-3-il]-ureido}-benzoesav vagy gyógyszerészetilegelfogadható sója vagy szolvátja. A találmány oltalmi körébe tartoznaktovábbá a találmány szerinti (+) enantiomert tartalmazógyógyszerkészítmények, valamint az enantiomerdús (I) képletűvegyületek előállítása is. Ó
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9910366.5A GB9910366D0 (en) | 1999-05-06 | 1999-05-06 | 1,5-Benzodiazepine Derivatives |
GBGB0008179.4A GB0008179D0 (en) | 2000-04-05 | 2000-04-05 | Chemical process |
PCT/EP2000/003982 WO2000068209A2 (en) | 1999-05-06 | 2000-05-04 | 1,5-benzodiazepine derivatives as cck-a receptor agonists |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP0201181A2 true HUP0201181A2 (hu) | 2002-12-28 |
HUP0201181A3 HUP0201181A3 (en) | 2003-10-28 |
Family
ID=26244033
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0201181A HUP0201181A3 (en) | 1999-05-06 | 2000-05-04 | 1,5-benzodiazepine derivatives, process for producing it and pharmaceutical composition containing it |
Country Status (21)
Country | Link |
---|---|
EP (1) | EP1212305A2 (hu) |
JP (1) | JP2002544200A (hu) |
KR (1) | KR20020012567A (hu) |
CN (1) | CN1161345C (hu) |
AR (1) | AR022044A1 (hu) |
AU (1) | AU4754800A (hu) |
BR (1) | BR0010338A (hu) |
CA (1) | CA2370801A1 (hu) |
CO (1) | CO5170461A1 (hu) |
CZ (1) | CZ20013988A3 (hu) |
HK (1) | HK1046138A1 (hu) |
HU (1) | HUP0201181A3 (hu) |
IL (1) | IL146124A0 (hu) |
MX (1) | MXPA01011267A (hu) |
MY (1) | MY138319A (hu) |
NO (1) | NO20015397D0 (hu) |
NZ (1) | NZ515048A (hu) |
PE (1) | PE20010110A1 (hu) |
PL (1) | PL351546A1 (hu) |
TR (1) | TR200103169T2 (hu) |
WO (1) | WO2000068209A2 (hu) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005035793A2 (en) * | 2003-10-09 | 2005-04-21 | Decode Genetics Ehf. | Cckar markers and haplotypes associated with extreme weight conditions |
AP2006003768A0 (en) | 2004-05-25 | 2006-10-31 | Pfizer Prod Inc | TetraazabenzoÄeÜazulene derivatives and analogs tehereof |
IL291985A (en) | 2019-10-07 | 2022-06-01 | Kallyope Inc | gpr119 agonists |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9307833D0 (en) * | 1993-04-15 | 1993-06-02 | Glaxo Inc | Modulators of cholecystokinin and gastrin |
-
2000
- 2000-05-03 AR ARP000102119A patent/AR022044A1/es unknown
- 2000-05-04 NZ NZ515048A patent/NZ515048A/xx unknown
- 2000-05-04 PE PE2000000415A patent/PE20010110A1/es not_active Application Discontinuation
- 2000-05-04 HU HU0201181A patent/HUP0201181A3/hu unknown
- 2000-05-04 MX MXPA01011267A patent/MXPA01011267A/es not_active Application Discontinuation
- 2000-05-04 IL IL14612400A patent/IL146124A0/xx unknown
- 2000-05-04 WO PCT/EP2000/003982 patent/WO2000068209A2/en not_active Application Discontinuation
- 2000-05-04 JP JP2000617189A patent/JP2002544200A/ja active Pending
- 2000-05-04 CA CA002370801A patent/CA2370801A1/en not_active Abandoned
- 2000-05-04 CN CNB008099324A patent/CN1161345C/zh not_active Expired - Fee Related
- 2000-05-04 AU AU47548/00A patent/AU4754800A/en not_active Abandoned
- 2000-05-04 BR BR0010338-1A patent/BR0010338A/pt not_active IP Right Cessation
- 2000-05-04 TR TR2001/03169T patent/TR200103169T2/xx unknown
- 2000-05-04 CO CO00031982A patent/CO5170461A1/es not_active Application Discontinuation
- 2000-05-04 EP EP00929488A patent/EP1212305A2/en not_active Withdrawn
- 2000-05-04 PL PL00351546A patent/PL351546A1/xx not_active Application Discontinuation
- 2000-05-04 KR KR1020017014075A patent/KR20020012567A/ko not_active Application Discontinuation
- 2000-05-04 MY MYPI20001917A patent/MY138319A/en unknown
- 2000-05-04 CZ CZ20013988A patent/CZ20013988A3/cs unknown
-
2001
- 2001-11-05 NO NO20015397A patent/NO20015397D0/no not_active Application Discontinuation
-
2002
- 2002-10-23 HK HK02107684.4A patent/HK1046138A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
EP1212305A2 (en) | 2002-06-12 |
CA2370801A1 (en) | 2000-11-16 |
AU4754800A (en) | 2000-11-21 |
IL146124A0 (en) | 2002-07-25 |
HK1046138A1 (zh) | 2002-12-27 |
CN1161345C (zh) | 2004-08-11 |
NO20015397L (no) | 2001-11-05 |
CZ20013988A3 (cs) | 2002-02-13 |
KR20020012567A (ko) | 2002-02-16 |
PE20010110A1 (es) | 2001-03-05 |
MXPA01011267A (es) | 2002-05-06 |
JP2002544200A (ja) | 2002-12-24 |
AR022044A1 (es) | 2002-09-04 |
CO5170461A1 (es) | 2002-06-27 |
BR0010338A (pt) | 2002-02-13 |
MY138319A (en) | 2009-05-29 |
NO20015397D0 (no) | 2001-11-05 |
CN1362949A (zh) | 2002-08-07 |
WO2000068209A3 (en) | 2001-03-01 |
PL351546A1 (en) | 2003-05-05 |
TR200103169T2 (tr) | 2002-04-22 |
NZ515048A (en) | 2004-01-30 |
HUP0201181A3 (en) | 2003-10-28 |
WO2000068209A2 (en) | 2000-11-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD9A | Lapse of provisional protection due to non-payment of fees |