HUP0103648A2 - Eljárás katéteralakú revascularisatio megelőzésére vagy késleltetésére - Google Patents

Eljárás katéteralakú revascularisatio megelőzésére vagy késleltetésére

Info

Publication number
HUP0103648A2
HUP0103648A2 HU0103648A HUP0103648A HUP0103648A2 HU P0103648 A2 HUP0103648 A2 HU P0103648A2 HU 0103648 A HU0103648 A HU 0103648A HU P0103648 A HUP0103648 A HU P0103648A HU P0103648 A2 HUP0103648 A2 HU P0103648A2
Authority
HU
Hungary
Prior art keywords
cholesterol
preventing
delaying
catheter
lowering agent
Prior art date
Application number
HU0103648A
Other languages
English (en)
Inventor
Donald Michael Black
Original Assignee
Warner-Lambert Co.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22289955&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP0103648(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Warner-Lambert Co. filed Critical Warner-Lambert Co.
Publication of HUP0103648A2 publication Critical patent/HUP0103648A2/hu
Publication of HUP0103648A3 publication Critical patent/HUP0103648A3/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4418Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • A61K31/366Lactones having six-membered rings, e.g. delta-lactones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/405Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Surgical Instruments (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

A találmány tárgya eljárás katéter alakú revascularisatio szükségesséválásának megelőzésére vagy késleltetésére szívkoszorúér-megbetegedésben szenvedő és ilyen kezelést igénylő betegekben,amelynek során agresszív lipidcsökkentést okozó menynyiségben egykoleszterincsökkentő szert adnak be. Az eljárást előnyösen úgy hajtjákvégre, hogy az eljárás során egy a HMG-CoA reduktáz inhibitoroksztatin osztályából kiválasztott koleszterincsökkentő szert, példáulatorvasztatint, pravasztatint, szimvasztatint, fluvasztatin vagymevasztatint adnak be. A beadható egyéb koleszterincsökkentő szerekközé tartoznak a fibrát osztály tagjai, amilyen például a gemfibrozil,a ciprofibrát és bezafibrát. Egy további megoldás értelmében az LDLkoleszterinnek a találmány szerinti agresszív mértékű csökkentéséhezegy karboxi-éter koleszterincsökkentő szert alkalmaznak, és ily módonelőzik meg vagy késleltetik egy szívkoszorúér-megbetegedésben szenvedőbetegben a katéteralapú revascularisatio szükségessé válását. Ó
HU0103648A 1998-09-30 1999-07-08 Method for preventing or delaying catheter-based revascularization HUP0103648A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10245798P 1998-09-30 1998-09-30
PCT/US1999/015385 WO2000018395A1 (en) 1998-09-30 1999-07-08 Method for preventing or delaying catheter-based revascularization

Publications (2)

Publication Number Publication Date
HUP0103648A2 true HUP0103648A2 (hu) 2003-08-28
HUP0103648A3 HUP0103648A3 (en) 2003-10-28

Family

ID=22289955

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0103648A HUP0103648A3 (en) 1998-09-30 1999-07-08 Method for preventing or delaying catheter-based revascularization

Country Status (35)

Country Link
US (1) US20080119561A1 (hu)
EP (1) EP1117392B1 (hu)
JP (1) JP2002525321A (hu)
KR (1) KR20010079955A (hu)
CN (1) CN1197565C (hu)
AP (1) AP1708A (hu)
AT (1) ATE260100T1 (hu)
AU (1) AU768474B2 (hu)
BG (1) BG105471A (hu)
BR (1) BR9914098A (hu)
CA (1) CA2343299C (hu)
CZ (1) CZ20011035A3 (hu)
DE (1) DE69915084T2 (hu)
DK (1) DK1117392T3 (hu)
EA (1) EA007427B1 (hu)
EE (1) EE200100199A (hu)
ES (1) ES2214872T3 (hu)
HK (1) HK1042436A1 (hu)
HR (1) HRP20010236A2 (hu)
HU (1) HUP0103648A3 (hu)
ID (1) ID30255A (hu)
IL (2) IL141953A0 (hu)
IS (1) IS5889A (hu)
NO (1) NO20011615L (hu)
NZ (1) NZ510500A (hu)
OA (1) OA11787A (hu)
PL (1) PL346980A1 (hu)
PT (1) PT1117392E (hu)
SI (1) SI1117392T1 (hu)
SK (1) SK4122001A3 (hu)
TR (1) TR200100901T2 (hu)
UA (1) UA73292C2 (hu)
WO (1) WO2000018395A1 (hu)
YU (1) YU23901A (hu)
ZA (1) ZA200102230B (hu)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001078747A1 (de) * 2000-04-18 2001-10-25 Bayer Aktiengesellschaft Verwendung von cse-hemmern zur behandlung von herzinsuffizienz
CA2414783A1 (en) * 2000-07-14 2002-01-24 Warner-Lambert Company Treatment of eating disorders using carboxyalkylethers

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5157025A (en) * 1991-04-01 1992-10-20 E. R. Squibb & Sons, Inc. Method for lowering serum cholesterol employing a phosphorus containing ace inhibitor alone or in combination with a cholesterol lowering drug
WO1995013063A1 (en) * 1993-11-09 1995-05-18 Merck & Co., Inc. HMG-CoA REDUCTASE INHIBITORS IN THE NORMALIZATION OF VASCULAR ENDOTHELIAL DYSFUNCTION
US5957916A (en) * 1994-05-25 1999-09-28 The Trustees Of Columbia University In The City Of New York Myocardial revascularization through the endocardial surface using a laser
US5545628A (en) * 1995-01-10 1996-08-13 Galephar P.R. Inc. Pharmaceutical composition containing fenofibrate
US5648387A (en) * 1995-03-24 1997-07-15 Warner-Lambert Company Carboxyalkylethers, formulations, and treatment of vascular diseases
CN1217656C (zh) * 1995-11-02 2005-09-07 沃尼尔·朗伯公司 用于调节脂浓度的方法和药物组合物
SE506272C2 (sv) * 1996-03-18 1997-11-24 Paul Edholm Förfarande och anordning för att bestämma bildläge och bildvinkel i en röntgenbild
IL117702A0 (en) * 1996-03-28 1996-07-23 Tel Aviv Medical Center Resear Drug for hyperlipoproteinemia
WO1998001100A2 (en) * 1996-07-09 1998-01-15 Merck & Co., Inc. Method for treating homozygous familial hypercholesterolemia
US5861399A (en) * 1996-07-17 1999-01-19 Heart Care Partners Methods and compositions for the rapid and enduring relief of inadequate myocardial function
US6180660B1 (en) * 1997-08-26 2001-01-30 Merck & Co., Inc. Cholesterol-lowering therapy
NZ503982A (en) * 1997-12-12 2002-03-28 Warner Lambert Co Statin-carboxyalkylether combinations useful for treating vascular disorders and diabetes mellitus

Also Published As

Publication number Publication date
AU4975099A (en) 2000-04-17
EA200100370A1 (ru) 2001-10-22
KR20010079955A (ko) 2001-08-22
DE69915084T2 (de) 2004-07-22
ZA200102230B (en) 2002-06-18
EP1117392B1 (en) 2004-02-25
WO2000018395A1 (en) 2000-04-06
CA2343299C (en) 2008-04-01
DK1117392T3 (da) 2004-06-14
JP2002525321A (ja) 2002-08-13
ES2214872T3 (es) 2004-09-16
HRP20010236A2 (en) 2002-04-30
OA11787A (en) 2005-07-26
TR200100901T2 (tr) 2001-08-21
NZ510500A (en) 2003-10-31
CA2343299A1 (en) 2000-04-06
CN1197565C (zh) 2005-04-20
IS5889A (is) 2001-03-14
PT1117392E (pt) 2004-07-30
UA73292C2 (en) 2005-07-15
ID30255A (id) 2001-11-15
YU23901A (sh) 2003-07-07
EE200100199A (et) 2002-06-17
EP1117392A1 (en) 2001-07-25
BG105471A (en) 2001-12-31
PL346980A1 (en) 2002-03-11
SK4122001A3 (en) 2002-06-04
NO20011615D0 (no) 2001-03-29
AU768474B2 (en) 2003-12-11
ATE260100T1 (de) 2004-03-15
IL141953A0 (en) 2002-03-10
CN1342072A (zh) 2002-03-27
DE69915084D1 (de) 2004-04-01
HUP0103648A3 (en) 2003-10-28
US20080119561A1 (en) 2008-05-22
IL141953A (en) 2006-07-05
EA007427B1 (ru) 2006-10-27
AP1708A (en) 2007-01-10
AP2001002112A0 (en) 2001-06-30
SI1117392T1 (en) 2004-06-30
CZ20011035A3 (cs) 2001-10-17
HK1042436A1 (en) 2002-08-16
NO20011615L (no) 2001-04-24
BR9914098A (pt) 2001-07-31

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Legal Events

Date Code Title Description
FD9A Lapse of provisional protection due to non-payment of fees