HUP0102241A2 - Rekombináns humán interferon-béta-1A (IFN-béta-1A) készítmémy - Google Patents

Rekombináns humán interferon-béta-1A (IFN-béta-1A) készítmémy

Info

Publication number
HUP0102241A2
HUP0102241A2 HU0102241A HUP0102241A HUP0102241A2 HU P0102241 A2 HUP0102241 A2 HU P0102241A2 HU 0102241 A HU0102241 A HU 0102241A HU P0102241 A HUP0102241 A HU P0102241A HU P0102241 A2 HUP0102241 A2 HU P0102241A2
Authority
HU
Hungary
Prior art keywords
betha
ifn
formulation
recombinant human
human interferon
Prior art date
Application number
HU0102241A
Other languages
English (en)
Inventor
John Alam
Susan Goelz
Mark Rogge
Original Assignee
Biogen Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen Inc. filed Critical Biogen Inc.
Publication of HUP0102241A2 publication Critical patent/HUP0102241A2/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A61K38/215—IFN-beta
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

A találmány tárgya folyékony gyógyszerkészítmény, amely hatóanyagkéntaz antivirális hatással rendelkező IFN-b-la 1. és 2. verziójáttartalmazza egy alkalmas pufferrel és humán szérumalbuminnal együtt. Akészítmény egészséges önkénteseken kipróbálva fokozottfarmakokinetikai és farmakodinámiás profilokat mutatott szubkután,intravénás és 30 perces intravénás úton történő beadás után. Atalálmány tárgya továbbá egy kit, amely alkalmas a folyékonygyógyszerkészítmény parenterális beadására. Ó
HU0102241A 1998-05-29 1998-05-29 Rekombináns humán interferon-béta-1A (IFN-béta-1A) készítmémy HUP0102241A2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1998/007242 WO1999062542A1 (en) 1998-05-29 1998-05-29 Recombinant human interferon beta-1a (ifn-beta-1a) formulation

Publications (1)

Publication Number Publication Date
HUP0102241A2 true HUP0102241A2 (hu) 2001-10-28

Family

ID=22266817

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0102241A HUP0102241A2 (hu) 1998-05-29 1998-05-29 Rekombináns humán interferon-béta-1A (IFN-béta-1A) készítmémy

Country Status (16)

Country Link
EP (1) EP1082132A1 (hu)
JP (1) JP2002516874A (hu)
KR (1) KR20010052454A (hu)
CN (1) CN1299285A (hu)
AU (1) AU8822598A (hu)
BR (1) BR9815966A (hu)
CA (1) CA2333063A1 (hu)
EA (1) EA200001252A1 (hu)
EE (1) EE200000694A (hu)
HU (1) HUP0102241A2 (hu)
IL (1) IL139933A0 (hu)
IS (1) IS5732A (hu)
NO (1) NO20006022L (hu)
SK (1) SK17762000A3 (hu)
TR (1) TR200003521T2 (hu)
WO (1) WO1999062542A1 (hu)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020025304A1 (en) * 2000-06-16 2002-02-28 Croze Edward M. Novel interferon for the treatment of multiple sclerosis
DE60130145T2 (de) * 2000-12-21 2008-05-15 Resuscitation Technologies, LLC, Santa Monica Stabile t3 zusammensetzungen und ihre anwendung
CN1325651C (zh) * 2001-05-24 2007-07-11 大连金威基因技术有限公司 人重组乙型干扰素的高效表达及其应用
CN1535724B (zh) * 2003-04-23 2012-09-05 北京金迪克生物技术研究所 重组人干扰素在制备预防严重性急性呼吸道综合征的药物的用途
PT2868315T (pt) * 2007-12-04 2017-09-04 Remedy Pharmaceuticals Inc Formulações melhoradas e métodos para liofilização e liofilizados assim produzidos
EP4211154A1 (en) * 2020-09-12 2023-07-19 Academia Sinica Re-folded human serum albumin and use thereof for anti-tumor

Also Published As

Publication number Publication date
IL139933A0 (en) 2002-02-10
AU8822598A (en) 1999-12-20
EE200000694A (et) 2002-06-17
WO1999062542A1 (en) 1999-12-09
CN1299285A (zh) 2001-06-13
BR9815966A (pt) 2001-02-28
EA200001252A1 (ru) 2001-06-25
EP1082132A1 (en) 2001-03-14
TR200003521T2 (tr) 2001-07-23
JP2002516874A (ja) 2002-06-11
IS5732A (is) 2000-11-24
NO20006022D0 (no) 2000-11-28
KR20010052454A (ko) 2001-06-25
SK17762000A3 (sk) 2001-07-10
CA2333063A1 (en) 1999-12-09
NO20006022L (no) 2001-01-26

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