HUP0101480A2 - Eljárás koleszterinből nyerhető baktérium-méretű partikulák előállítására - Google Patents
Eljárás koleszterinből nyerhető baktérium-méretű partikulák előállításáraInfo
- Publication number
- HUP0101480A2 HUP0101480A2 HU0101480A HUP0101480A HUP0101480A2 HU P0101480 A2 HUP0101480 A2 HU P0101480A2 HU 0101480 A HU0101480 A HU 0101480A HU P0101480 A HUP0101480 A HU P0101480A HU P0101480 A2 HUP0101480 A2 HU P0101480A2
- Authority
- HU
- Hungary
- Prior art keywords
- cholesterol
- producing particles
- bacterium size
- cholesterol antibody
- bacterium
- Prior art date
Links
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 title abstract 4
- 239000002245 particle Substances 0.000 title abstract 3
- 235000012000 cholesterol Nutrition 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 241000894006 Bacteria Species 0.000 title 1
- 230000003627 anti-cholesterol Effects 0.000 abstract 3
- 239000002502 liposome Substances 0.000 abstract 2
- 239000000654 additive Substances 0.000 abstract 1
- 230000007812 deficiency Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000003053 immunization Effects 0.000 abstract 1
- 238000002649 immunization Methods 0.000 abstract 1
- 230000016784 immunoglobulin production Effects 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 238000001990 intravenous administration Methods 0.000 abstract 1
- 238000010253 intravenous injection Methods 0.000 abstract 1
- 230000000087 stabilizing effect Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1274—Non-vesicle bilayer structures, e.g. liquid crystals, tubules, cubic phases, cochleates; Sponge phases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1277—Processes for preparing; Proliposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dispersion Chemistry (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
A találmány tárgya olyan eljárás melynek segítségével nagy tisztaságúkoleszterinből mikrokokkusz méretű liposoma partikulák állíthatók elő,amelyek alkalmasak intravenás injekció formájában aktív immunizálássalantikoleszterin antitesttermelés kiváltására és az antikoleszterinantitesthiány vagy antikoleszterin antitesttiter-csökkenéskövetkeztében kialakuló betegségek gyógyítására. A liposoma partikulaszuszpenzió intravenás beadása esetén a stabilizáló szerepet önmagábanismert adalékanyagok, és izotóniás körülményeket biztosítósegédanyagok biztosítják. Ó
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU0101480A HUP0101480A2 (hu) | 2001-04-11 | 2001-04-11 | Eljárás koleszterinből nyerhető baktérium-méretű partikulák előállítására |
PCT/HU2002/000029 WO2002083100A1 (en) | 2001-04-11 | 2002-04-10 | Liposomes consisting mainly of cholesterol |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HU0101480A HUP0101480A2 (hu) | 2001-04-11 | 2001-04-11 | Eljárás koleszterinből nyerhető baktérium-méretű partikulák előállítására |
Publications (2)
Publication Number | Publication Date |
---|---|
HU0101480D0 HU0101480D0 (en) | 2001-06-28 |
HUP0101480A2 true HUP0101480A2 (hu) | 2004-01-28 |
Family
ID=89979198
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0101480A HUP0101480A2 (hu) | 2001-04-11 | 2001-04-11 | Eljárás koleszterinből nyerhető baktérium-méretű partikulák előállítására |
Country Status (2)
Country | Link |
---|---|
HU (1) | HUP0101480A2 (hu) |
WO (1) | WO2002083100A1 (hu) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HUP0204064A2 (hu) * | 2002-11-26 | 2005-07-28 | István Horváth | Eljárás koleszterinből nyerhető baktérium méretű partikulák előállítására, valamint az eljárással előállított partikula |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5043107A (en) * | 1986-08-21 | 1991-08-27 | Vestar Research, Inc. | Preparation small unilamellar vesicles including polyene antifungal antibiotics |
US6214388B1 (en) * | 1994-11-09 | 2001-04-10 | The Regents Of The University Of California | Immunoliposomes that optimize internalization into target cells |
-
2001
- 2001-04-11 HU HU0101480A patent/HUP0101480A2/hu unknown
-
2002
- 2002-04-10 WO PCT/HU2002/000029 patent/WO2002083100A1/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO2002083100A1 (en) | 2002-10-24 |
HU0101480D0 (en) | 2001-06-28 |
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