HUP0100352A2 - Compositions derived from mycobacterium vaccae and methods for their use - Google Patents
Compositions derived from mycobacterium vaccae and methods for their useInfo
- Publication number
- HUP0100352A2 HUP0100352A2 HU0100352A HUP0100352A HUP0100352A2 HU P0100352 A2 HUP0100352 A2 HU P0100352A2 HU 0100352 A HU0100352 A HU 0100352A HU P0100352 A HUP0100352 A HU P0100352A HU P0100352 A2 HUP0100352 A2 HU P0100352A2
- Authority
- HU
- Hungary
- Prior art keywords
- vaccae
- methods
- depleted
- delipidated
- mycobacterium vaccae
- Prior art date
Links
- 241000187644 Mycobacterium vaccae Species 0.000 title abstract 6
- 238000000034 method Methods 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 3
- HVCOBJNICQPDBP-UHFFFAOYSA-N 3-[3-[3,5-dihydroxy-6-methyl-4-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxyoxan-2-yl]oxydecanoyloxy]decanoic acid;hydrate Chemical compound O.OC1C(OC(CC(=O)OC(CCCCCCC)CC(O)=O)CCCCCCC)OC(C)C(O)C1OC1C(O)C(O)C(O)C(C)O1 HVCOBJNICQPDBP-UHFFFAOYSA-N 0.000 abstract 2
- 229930186217 Glycolipid Natural products 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- SATHPVQTSSUFFW-UHFFFAOYSA-N 4-[6-[(3,5-dihydroxy-4-methoxyoxan-2-yl)oxymethyl]-3,5-dihydroxy-4-methoxyoxan-2-yl]oxy-2-(hydroxymethyl)-6-methyloxane-3,5-diol Chemical compound OC1C(OC)C(O)COC1OCC1C(O)C(OC)C(O)C(OC2C(C(CO)OC(C)C2O)O)O1 SATHPVQTSSUFFW-UHFFFAOYSA-N 0.000 abstract 1
- 229920000189 Arabinogalactan Polymers 0.000 abstract 1
- 239000001904 Arabinogalactan Substances 0.000 abstract 1
- 208000035473 Communicable disease Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 235000019312 arabinogalactan Nutrition 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 239000000706 filtrate Substances 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 208000026278 immune system disease Diseases 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Abstract
A találmány olyan kompozíciókkal foglalkozik, amelyek jelen vannakMycobacterium vaccae törzsben vagy abból származhatnak, foglalkoziktovábbá eljárásokkal ezeknek a kompozícióknak az alkalmazására olyanrendellenességek kezelésére, megelőzésére és kimutatására, mint afertőző betegségek, immunrendellenességek és rák. A találmány továbbáfoglalkozik eljárással immunválasz fokozására valamely antigénre,amely eljárás magában foglalja M. vaccae tenyészet szűrlet,lipidmentesített M. vaccae sejtek, lipidmentesített és glikolipid-mentesített, mikolsavra kimerített M. vaccae sejtek vagylipidmentesített és glikolipid-mentesített, mikolsavra ésarabinogalaktánra kimerített M. vaccae sejtek beadását. ÓThe invention relates to compositions that are present in or may be derived from Mycobacterium vaccae, and further to methods of using these compositions for the treatment, prevention, and detection of disorders such as infectious diseases, immune disorders, and cancer. The invention also relates to a method for enhancing an immune response to an antigen, which method includes M. vaccae culture filtrate, delipidated M. vaccae cells, delipidated and glycolipid-depleted M. vaccae cells depleted of mycolic acid, or delipidated and glycolipid-depleted M. vaccae cells depleted of mycolic acid and arabinogalactan. administration. HE
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US99662497A | 1997-12-23 | 1997-12-23 | |
US08/997,080 US5968524A (en) | 1997-12-23 | 1997-12-23 | Methods and compounds for the treatment of immunologically-mediated psoriasis |
US08/997,362 US5985287A (en) | 1996-08-29 | 1997-12-23 | Compounds and methods for treatment and diagnosis of mycobacterial infections |
US09/095,855 US6160093A (en) | 1996-08-29 | 1998-06-11 | Compounds and methods for treatment and diagnosis of mycobacterial infections |
US15618198A | 1998-09-17 | 1998-09-17 | |
US09/205,426 US6406704B1 (en) | 1996-08-29 | 1998-12-04 | Compounds and methods for treatment and diagnosis of mycobacterial infections |
PCT/NZ1998/000189 WO1999032634A2 (en) | 1997-12-23 | 1998-12-23 | Compositions derived from mycobacterium vaccae and methods for their use |
Publications (1)
Publication Number | Publication Date |
---|---|
HUP0100352A2 true HUP0100352A2 (en) | 2001-06-28 |
Family
ID=27557521
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0100352A HUP0100352A2 (en) | 1997-12-23 | 1998-12-23 | Compositions derived from mycobacterium vaccae and methods for their use |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP1044273A2 (en) |
JP (1) | JP2002514385A (en) |
CN (1) | CN1294632A (en) |
AU (1) | AU746311B2 (en) |
BR (1) | BR9814432A (en) |
CA (1) | CA2315539A1 (en) |
HU (1) | HUP0100352A2 (en) |
ID (1) | ID26327A (en) |
IL (1) | IL136821A0 (en) |
MX (1) | MXPA00006168A (en) |
NO (1) | NO20003261L (en) |
NZ (1) | NZ505834A (en) |
PL (1) | PL341697A1 (en) |
TR (1) | TR200001948T2 (en) |
WO (1) | WO1999032634A2 (en) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6569436B1 (en) | 1998-10-05 | 2003-05-27 | The Malaghan Institute Of Medical Research | Method of using a vaccine |
JP4415200B2 (en) * | 1999-01-29 | 2010-02-17 | 大塚製薬株式会社 | Late-growing mycobacterial polypeptide |
GB9903539D0 (en) | 1999-02-16 | 1999-04-07 | Stanford Rook Ltd | Therapy using M.Vaccae |
US6350457B1 (en) * | 1999-06-02 | 2002-02-26 | Genesis Research & Development Corporation Limited | Methods and compounds for the treatment of immunologically-mediated diseases using mycobacterium vaccae |
MXPA01013097A (en) * | 1999-07-12 | 2002-06-04 | Genesis Res & Dev Corp Ltd | Compounds for treatment of infectious and immune system disorders and methods for their use. |
CA2381139A1 (en) * | 1999-08-31 | 2001-03-08 | Michael Niederweis | Method for the production of a channel forming protein |
WO2001016285A2 (en) | 1999-08-31 | 2001-03-08 | Novozymes A/S | Novel proteases and variants thereof |
US7217554B2 (en) | 1999-08-31 | 2007-05-15 | Novozymes A/S | Proteases and variants thereof |
US6361776B1 (en) * | 1999-12-06 | 2002-03-26 | Genesis Research & Development Corp. Ltd. | Compounds isolated from M. vaccae and their use in modulation of immune responses |
US20030108527A1 (en) * | 1999-12-28 | 2003-06-12 | Tsukasa Seya | Maturation-promoting agent for immature dendrtic cells |
AUPQ761200A0 (en) * | 2000-05-19 | 2000-06-15 | Hunter Immunology Limited | Compositions and methods for treatment of mucosal infections |
WO2002094184A2 (en) * | 2001-05-11 | 2002-11-28 | Corixa Corporation | Vaccines for the treatment of autoimmune disease |
US20030147861A1 (en) * | 2001-07-26 | 2003-08-07 | Genesis Research And Development Corporation Limited | Compounds and methods for the modulation of immune responses |
AU2002353366A1 (en) * | 2001-12-10 | 2003-06-23 | Bakulesh Mafatlal Khamar | The process of manufacturing a pharmaceutical composition useful for management of cancer |
GB0303507D0 (en) | 2003-02-14 | 2003-03-19 | Novartis Ag | Organic compounds |
EP3092000A1 (en) * | 2014-01-09 | 2016-11-16 | Transgene SA | Fusion of heterooligomeric mycobacterial antigens |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8919321D0 (en) * | 1989-08-25 | 1989-10-11 | Univ London | Treatment of chronic inflammatory conditions |
GB9203814D0 (en) * | 1992-02-21 | 1992-04-08 | Univ London | Treatment of long term auto-immune conditions |
US6284255B1 (en) * | 1996-08-29 | 2001-09-04 | Genesis Research & Development Corporation Limited | Compounds and methods for treatment and diagnosis of mycobacterial infections |
-
1998
- 1998-12-23 BR BR9814432-4A patent/BR9814432A/en not_active IP Right Cessation
- 1998-12-23 PL PL98341697A patent/PL341697A1/en unknown
- 1998-12-23 MX MXPA00006168A patent/MXPA00006168A/en unknown
- 1998-12-23 WO PCT/NZ1998/000189 patent/WO1999032634A2/en not_active Application Discontinuation
- 1998-12-23 IL IL13682198A patent/IL136821A0/en unknown
- 1998-12-23 HU HU0100352A patent/HUP0100352A2/en unknown
- 1998-12-23 JP JP2000525553A patent/JP2002514385A/en active Pending
- 1998-12-23 AU AU18936/99A patent/AU746311B2/en not_active Ceased
- 1998-12-23 NZ NZ505834A patent/NZ505834A/en unknown
- 1998-12-23 ID IDW20001433A patent/ID26327A/en unknown
- 1998-12-23 CA CA002315539A patent/CA2315539A1/en not_active Abandoned
- 1998-12-23 EP EP98963665A patent/EP1044273A2/en not_active Withdrawn
- 1998-12-23 CN CN98813781A patent/CN1294632A/en active Pending
- 1998-12-23 TR TR2000/01948T patent/TR200001948T2/en unknown
-
2000
- 2000-06-22 NO NO20003261A patent/NO20003261L/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
AU1893699A (en) | 1999-07-12 |
IL136821A0 (en) | 2001-06-14 |
ID26327A (en) | 2000-12-14 |
BR9814432A (en) | 2000-10-10 |
PL341697A1 (en) | 2001-04-23 |
NO20003261D0 (en) | 2000-06-22 |
JP2002514385A (en) | 2002-05-21 |
TR200001948T2 (en) | 2001-02-21 |
NO20003261L (en) | 2000-08-22 |
CA2315539A1 (en) | 1999-07-01 |
MXPA00006168A (en) | 2005-02-24 |
WO1999032634A3 (en) | 1999-12-02 |
WO1999032634A2 (en) | 1999-07-01 |
NZ505834A (en) | 2002-12-20 |
CN1294632A (en) | 2001-05-09 |
AU746311B2 (en) | 2002-04-18 |
EP1044273A2 (en) | 2000-10-18 |
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