HUP0004976A2 - Pharmaceutical compositions comprising copper(1) oxide and/or elemental copper for the treatment and prevention of mycosis and other infections, process for the preparation of the active component - Google Patents
Pharmaceutical compositions comprising copper(1) oxide and/or elemental copper for the treatment and prevention of mycosis and other infections, process for the preparation of the active component Download PDFInfo
- Publication number
- HUP0004976A2 HUP0004976A2 HU0004976A HUP0004976A HUP0004976A2 HU P0004976 A2 HUP0004976 A2 HU P0004976A2 HU 0004976 A HU0004976 A HU 0004976A HU P0004976 A HUP0004976 A HU P0004976A HU P0004976 A2 HUP0004976 A2 HU P0004976A2
- Authority
- HU
- Hungary
- Prior art keywords
- copper
- candida
- oxide
- disease
- treatment
- Prior art date
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- 239000010949 copper Substances 0.000 title claims abstract description 165
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 title claims abstract description 113
- 229910052802 copper Inorganic materials 0.000 title claims abstract description 113
- 238000011282 treatment Methods 0.000 title claims abstract description 59
- 238000002360 preparation method Methods 0.000 title claims abstract description 51
- 230000002265 prevention Effects 0.000 title claims abstract description 13
- 206010017533 Fungal infection Diseases 0.000 title claims abstract description 10
- 238000000034 method Methods 0.000 title claims description 36
- 208000015181 infectious disease Diseases 0.000 title claims description 24
- 230000008569 process Effects 0.000 title claims description 13
- LBJNMUFDOHXDFG-UHFFFAOYSA-N copper;hydrate Chemical compound O.[Cu].[Cu] LBJNMUFDOHXDFG-UHFFFAOYSA-N 0.000 title description 2
- 239000008194 pharmaceutical composition Substances 0.000 title description 2
- 208000024386 fungal infectious disease Diseases 0.000 title 1
- BERDEBHAJNAUOM-UHFFFAOYSA-N copper(i) oxide Chemical compound [Cu]O[Cu] BERDEBHAJNAUOM-UHFFFAOYSA-N 0.000 claims abstract description 165
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims abstract description 44
- 239000011668 ascorbic acid Substances 0.000 claims abstract description 21
- 235000010323 ascorbic acid Nutrition 0.000 claims abstract description 21
- 229960005070 ascorbic acid Drugs 0.000 claims abstract description 21
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- 230000001580 bacterial effect Effects 0.000 claims abstract description 10
- JPVYNHNXODAKFH-UHFFFAOYSA-N Cu2+ Chemical compound [Cu+2] JPVYNHNXODAKFH-UHFFFAOYSA-N 0.000 claims abstract description 9
- 239000003638 chemical reducing agent Substances 0.000 claims abstract description 9
- 239000011573 trace mineral Substances 0.000 claims abstract description 9
- 235000013619 trace mineral Nutrition 0.000 claims abstract description 9
- 235000000346 sugar Nutrition 0.000 claims abstract description 7
- BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 claims abstract description 6
- 229910052736 halogen Inorganic materials 0.000 claims abstract description 5
- 239000007864 aqueous solution Substances 0.000 claims abstract description 4
- 229910052794 bromium Inorganic materials 0.000 claims abstract description 3
- 229910052801 chlorine Inorganic materials 0.000 claims abstract description 3
- 229910052731 fluorine Inorganic materials 0.000 claims abstract description 3
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- 239000000203 mixture Substances 0.000 claims description 49
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- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 33
- 208000024891 symptom Diseases 0.000 claims description 29
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- 230000000694 effects Effects 0.000 claims description 28
- MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical compound OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 claims description 25
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims description 25
- 230000001225 therapeutic effect Effects 0.000 claims description 25
- 239000011701 zinc Substances 0.000 claims description 25
- 229910052725 zinc Inorganic materials 0.000 claims description 25
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- 230000001857 anti-mycotic effect Effects 0.000 claims description 17
- 239000002543 antimycotic Substances 0.000 claims description 17
- -1 oxalate ions Chemical class 0.000 claims description 17
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 16
- 230000002538 fungal effect Effects 0.000 claims description 16
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- 241000222122 Candida albicans Species 0.000 claims description 15
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 claims description 14
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- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 12
- ZOKXTWBITQBERF-UHFFFAOYSA-N Molybdenum Chemical compound [Mo] ZOKXTWBITQBERF-UHFFFAOYSA-N 0.000 claims description 12
- 229910052750 molybdenum Inorganic materials 0.000 claims description 12
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- 239000000126 substance Substances 0.000 claims description 11
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims description 10
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- 102000004190 Enzymes Human genes 0.000 claims description 9
- 108090000790 Enzymes Proteins 0.000 claims description 9
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 claims description 9
- 239000003242 anti bacterial agent Substances 0.000 claims description 9
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- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 7
- 229910021529 ammonia Inorganic materials 0.000 claims description 7
- ARUVKPQLZAKDPS-UHFFFAOYSA-L copper(II) sulfate Chemical compound [Cu+2].[O-][S+2]([O-])([O-])[O-] ARUVKPQLZAKDPS-UHFFFAOYSA-L 0.000 claims description 7
- 210000000214 mouth Anatomy 0.000 claims description 7
- 238000002560 therapeutic procedure Methods 0.000 claims description 7
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 claims description 6
- 239000004354 Hydroxyethyl cellulose Substances 0.000 claims description 6
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 claims description 6
- 206010028813 Nausea Diseases 0.000 claims description 6
- XLOMVQKBTHCTTD-UHFFFAOYSA-N Zinc monoxide Chemical compound [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 claims description 6
- 239000000654 additive Substances 0.000 claims description 6
- 210000001072 colon Anatomy 0.000 claims description 6
- JNRBLFVQPTZFAG-UHFFFAOYSA-L copper;selenite Chemical compound [Cu+2].[O-][Se]([O-])=O JNRBLFVQPTZFAG-UHFFFAOYSA-L 0.000 claims description 6
- 230000006378 damage Effects 0.000 claims description 6
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- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims description 5
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- 230000009885 systemic effect Effects 0.000 claims description 5
- PEUPCBAALXHYHP-UHFFFAOYSA-L zinc;selenite Chemical compound [Zn+2].[O-][Se]([O-])=O PEUPCBAALXHYHP-UHFFFAOYSA-L 0.000 claims description 5
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- ZPEJZWGMHAKWNL-UHFFFAOYSA-L zinc;oxalate Chemical compound [Zn+2].[O-]C(=O)C([O-])=O ZPEJZWGMHAKWNL-UHFFFAOYSA-L 0.000 claims description 3
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 claims description 2
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Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU0004976A HUP0004976A2 (en) | 2000-12-19 | 2000-12-19 | Pharmaceutical compositions comprising copper(1) oxide and/or elemental copper for the treatment and prevention of mycosis and other infections, process for the preparation of the active component |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU0004976A HUP0004976A2 (en) | 2000-12-19 | 2000-12-19 | Pharmaceutical compositions comprising copper(1) oxide and/or elemental copper for the treatment and prevention of mycosis and other infections, process for the preparation of the active component |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HU0004976D0 HU0004976D0 (enrdf_load_html_response) | 2001-02-28 |
| HUP0004976A2 true HUP0004976A2 (en) | 2002-10-28 |
Family
ID=89978869
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0004976A HUP0004976A2 (en) | 2000-12-19 | 2000-12-19 | Pharmaceutical compositions comprising copper(1) oxide and/or elemental copper for the treatment and prevention of mycosis and other infections, process for the preparation of the active component |
Country Status (1)
| Country | Link |
|---|---|
| HU (1) | HUP0004976A2 (enrdf_load_html_response) |
-
2000
- 2000-12-19 HU HU0004976A patent/HUP0004976A2/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HU0004976D0 (enrdf_load_html_response) | 2001-02-28 |
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