HUP0004900A3 - Pharmaceutical compositions for treating disease-related or drug-induced dyskinesias containing piperidine derivatives as nmda receptor antagonist as active ingredient - Google Patents
Pharmaceutical compositions for treating disease-related or drug-induced dyskinesias containing piperidine derivatives as nmda receptor antagonist as active ingredientInfo
- Publication number
- HUP0004900A3 HUP0004900A3 HU0004900A HUP0004900A HUP0004900A3 HU P0004900 A3 HUP0004900 A3 HU P0004900A3 HU 0004900 A HU0004900 A HU 0004900A HU P0004900 A HUP0004900 A HU P0004900A HU P0004900 A3 HUP0004900 A3 HU P0004900A3
- Authority
- HU
- Hungary
- Prior art keywords
- drug
- active ingredient
- pharmaceutical compositions
- receptor antagonist
- nmda receptor
- Prior art date
Links
- 229940099433 NMDA receptor antagonist Drugs 0.000 title 1
- 239000004480 active ingredient Substances 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 208000009985 drug-induced dyskinesia Diseases 0.000 title 1
- 239000003703 n methyl dextro aspartic acid receptor blocking agent Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000003053 piperidines Chemical class 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/453—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6315697P | 1997-10-24 | 1997-10-24 | |
| PCT/US1998/019357 WO1999021539A1 (en) | 1997-10-24 | 1998-09-16 | Method for treating disease-related or drug-induced dyskinesias |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0004900A2 HUP0004900A2 (hu) | 2001-06-28 |
| HUP0004900A3 true HUP0004900A3 (en) | 2002-03-28 |
Family
ID=22047302
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0004900A HUP0004900A3 (en) | 1997-10-24 | 1998-09-16 | Pharmaceutical compositions for treating disease-related or drug-induced dyskinesias containing piperidine derivatives as nmda receptor antagonist as active ingredient |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US6284776B1 (hu) |
| EP (1) | EP1024799A1 (hu) |
| JP (1) | JP2001520988A (hu) |
| KR (1) | KR20010024548A (hu) |
| AU (1) | AU760800B2 (hu) |
| BR (1) | BR9814867A (hu) |
| CA (1) | CA2299400C (hu) |
| HU (1) | HUP0004900A3 (hu) |
| IL (1) | IL134363A0 (hu) |
| IS (1) | IS5384A (hu) |
| NO (1) | NO20001893L (hu) |
| NZ (1) | NZ502785A (hu) |
| PL (1) | PL340080A1 (hu) |
| WO (1) | WO1999021539A1 (hu) |
| ZA (1) | ZA989693B (hu) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005506292A (ja) * | 2001-03-08 | 2005-03-03 | エモリー ユニバーシティ | ｐＨに依存するＮＭＤＡレセプターアンタゴニスト |
| CA2381630A1 (en) * | 2001-04-23 | 2002-10-23 | Leonard Theodore Meltzer | Method for preventing dyskinesias |
| ES2312603T3 (es) | 2001-07-24 | 2009-03-01 | Richter Gedeon Nyrt | Derivados de piperidina como antagonistas del receptor nmda. |
| US7160913B2 (en) * | 2002-09-13 | 2007-01-09 | Thomas Jefferson University | Methods and kit for treating Parkinson's disease |
| MXPA06004038A (es) * | 2003-10-08 | 2006-06-28 | Pfizer | Compuestos de 1-'2-(4-hidroxifenil)-2-hidroxietil-piperidin-4-ol como antagonsitas del receptor n-metil-d-aspartato. |
| NZ582917A (en) * | 2007-06-29 | 2013-01-25 | Univ Emory | Nmda receptor antagonists for neuroprotection |
| US8951968B2 (en) | 2009-10-05 | 2015-02-10 | Northwestern University | Methods of treating depression and other related diseases |
| SG10201800159QA (en) | 2011-11-22 | 2018-02-27 | Univ California | Cysteamine and/or cystamine for treating ischemic injury |
| US10752588B2 (en) | 2014-12-19 | 2020-08-25 | The Broad Institute, Inc. | Dopamine D2 receptor ligands |
| US10633336B2 (en) | 2014-12-19 | 2020-04-28 | The Broad Institute, Inc. | Dopamine D2 receptor ligands |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR5733M (hu) | 1966-09-27 | 1968-01-22 | ||
| US5272160A (en) | 1989-05-17 | 1993-12-21 | Pfizer Inc | 2-piperidino-1-alkanol derivatives as antiischemic agents |
| EP0497843A4 (en) * | 1989-10-27 | 1992-09-23 | The Du Pont Merck Pharmaceutical Company | (n-phthalimidoalkyl) piperidines |
| US5356906A (en) * | 1989-10-27 | 1994-10-18 | The Du Pont Merck Pharmaceutical Company | (N-phthalimidoalkyl) piperidines useful as treatments for psychosis |
| US5116846A (en) * | 1990-03-28 | 1992-05-26 | Du Pont Merck Pharmaceutical Company | N-aralkyl piperidine derivatives as psychotropic drugs |
| EP0591426A4 (en) * | 1991-06-27 | 1996-08-21 | Univ Virginia Commonwealth | Sigma receptor ligands and the use thereof |
| US5364867A (en) * | 1992-11-30 | 1994-11-15 | Sterling Winthrop Inc. | 4-phenylpiperdine agents for treating cns disorders |
| TW281670B (hu) | 1993-09-02 | 1996-07-21 | Hoffmann La Roche | |
| FR2717080B1 (fr) | 1994-03-09 | 1996-12-13 | Synthelabo | Utilisation de l'éliprodil et de ses énantiomères pour la préparation de médicaments utiles dans le traitement des neuropathies périphériques et des maladies neurodégénératives centrales. |
| FR2717810B1 (fr) * | 1994-03-22 | 1996-04-26 | Adir | Nouvelles aminoalkyl benzoxazolinones et benzothiazolinones, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
| EP0828513B1 (en) * | 1995-05-26 | 2004-01-21 | Pfizer Inc. | Combinations for the treatment of parkinsonism containing selective nmda antagonists |
| ZA9610745B (en) * | 1995-12-22 | 1997-06-24 | Warner Lambert Co | 4-Subsituted piperidine analogs and their use as subtype selective nmda receptor antagonists |
| ZA9610741B (en) | 1995-12-22 | 1997-06-24 | Warner Lambert Co | 4-Substituted piperidine analogs and their use as subtype selective nmda receptor antagonists |
-
1998
- 1998-09-16 JP JP2000517698A patent/JP2001520988A/ja not_active Abandoned
- 1998-09-16 HU HU0004900A patent/HUP0004900A3/hu unknown
- 1998-09-16 US US09/485,348 patent/US6284776B1/en not_active Expired - Fee Related
- 1998-09-16 BR BR9814867-2A patent/BR9814867A/pt not_active Application Discontinuation
- 1998-09-16 IL IL13436398A patent/IL134363A0/xx unknown
- 1998-09-16 CA CA002299400A patent/CA2299400C/en not_active Expired - Fee Related
- 1998-09-16 EP EP98946093A patent/EP1024799A1/en not_active Ceased
- 1998-09-16 PL PL98340080A patent/PL340080A1/xx unknown
- 1998-09-16 WO PCT/US1998/019357 patent/WO1999021539A1/en not_active Application Discontinuation
- 1998-09-16 NZ NZ502785A patent/NZ502785A/xx unknown
- 1998-09-16 AU AU93181/98A patent/AU760800B2/en not_active Ceased
- 1998-09-16 KR KR1020007004360A patent/KR20010024548A/ko not_active Application Discontinuation
- 1998-10-23 ZA ZA989693A patent/ZA989693B/xx unknown
-
2000
- 2000-02-25 IS IS5384A patent/IS5384A/is unknown
- 2000-04-12 NO NO20001893A patent/NO20001893L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| AU760800B2 (en) | 2003-05-22 |
| AU9318198A (en) | 1999-05-17 |
| HUP0004900A2 (hu) | 2001-06-28 |
| IL134363A0 (en) | 2001-04-30 |
| KR20010024548A (ko) | 2001-03-26 |
| NZ502785A (en) | 2003-03-28 |
| US6284776B1 (en) | 2001-09-04 |
| PL340080A1 (en) | 2001-01-15 |
| JP2001520988A (ja) | 2001-11-06 |
| ZA989693B (en) | 1999-04-29 |
| EP1024799A1 (en) | 2000-08-09 |
| NO20001893D0 (no) | 2000-04-12 |
| CA2299400A1 (en) | 1999-05-06 |
| BR9814867A (pt) | 2000-10-03 |
| NO20001893L (no) | 2000-04-12 |
| CA2299400C (en) | 2004-04-27 |
| WO1999021539A1 (en) | 1999-05-06 |
| IS5384A (is) | 2000-02-25 |
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