HUP0004245A2 - Terápiásan hatékony készítmények - Google Patents

Terápiásan hatékony készítmények

Info

Publication number
HUP0004245A2
HUP0004245A2 HU0004245A HUP0004245A HUP0004245A2 HU P0004245 A2 HUP0004245 A2 HU P0004245A2 HU 0004245 A HU0004245 A HU 0004245A HU P0004245 A HUP0004245 A HU P0004245A HU P0004245 A2 HUP0004245 A2 HU P0004245A2
Authority
HU
Hungary
Prior art keywords
component
rectum
stomach
digestive system
dissolution
Prior art date
Application number
HU0004245A
Other languages
English (en)
Inventor
Fiona Kate Gardiner
Original Assignee
Reckitt & Colman Products Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reckitt & Colman Products Ltd. filed Critical Reckitt & Colman Products Ltd.
Publication of HUP0004245A2 publication Critical patent/HUP0004245A2/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/02Suppositories; Bougies; Bases therefor; Ovules
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/075Ethers or acetals
    • A61K31/085Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/12Ketones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4525Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0031Rectum, anus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1635Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/284Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4891Coated capsules; Multilayered drug free capsule shells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A találmány tárgya orális gyógyszerkészítmény irritációs bélszindróma, hasmenés, székrekedés, hasi fájdalom és/vagy püffedés vagyhasi felfúvódás kezelésére történő felhasználásra, amely készítmény i)kapszaicint vagy reziniferatoxint, azok gyógyászatilag elfogadhatósóit, analógjait és/vagy származékait a) komponensként; és ii) b)komponensként valamely gyógyszerészetileg elfogadható vívőanyagotfoglal magába, ahol a gyógyszerkészítmény dózisegység formájaozmotikus kioldódású vagy valamely enterikus bevonat tartalmaz,amelyből az a) komponens az emésztőszerv rendszerben, a gyomor és avégbél között oldódik ki és a b) komponens lehetővé teszi az a)komponens kioldódását az emésztőszerv rendszerben a gyomor és a végbélközött. Ó
HU0004245A 1997-06-10 1998-06-08 Terápiásan hatékony készítmények HUP0004245A2 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9711962.2A GB9711962D0 (en) 1997-06-10 1997-06-10 Therapeutically active compositions
PCT/GB1998/001673 WO1998056356A1 (en) 1997-06-10 1998-06-08 Therapeutically active compositions

Publications (1)

Publication Number Publication Date
HUP0004245A2 true HUP0004245A2 (hu) 2001-08-28

Family

ID=10813845

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0004245A HUP0004245A2 (hu) 1997-06-10 1998-06-08 Terápiásan hatékony készítmények

Country Status (17)

Country Link
US (1) US6201014B1 (hu)
EP (1) EP0988028B1 (hu)
JP (1) JP2002513418A (hu)
KR (1) KR20010013618A (hu)
CN (1) CN1198594C (hu)
AR (1) AR012960A1 (hu)
AT (1) ATE262892T1 (hu)
AU (1) AU737606B2 (hu)
BR (1) BR9809994A (hu)
CA (1) CA2291796C (hu)
DE (1) DE69822822T2 (hu)
GB (3) GB9711962D0 (hu)
HU (1) HUP0004245A2 (hu)
ID (1) ID22878A (hu)
PL (1) PL337337A1 (hu)
WO (1) WO1998056356A1 (hu)
ZA (1) ZA984920B (hu)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6790207B2 (en) * 1998-06-04 2004-09-14 Curon Medical, Inc. Systems and methods for applying a selected treatment agent into contact with tissue to treat disorders of the gastrointestinal tract
US6802841B2 (en) * 1998-06-04 2004-10-12 Curon Medical, Inc. Systems and methods for applying a selected treatment agent into contact with tissue to treat sphincter dysfunction
US20110071468A1 (en) * 1998-06-04 2011-03-24 Mederi Therapeutics, Inc. Systems and methods for applying a selected treatment agent into contact with tissue to treat sphincter dysfunction
GB9812426D0 (en) 1998-06-10 1998-08-05 Reckitt & Colmann Prod Ltd Improvements in or relating to organic compositions
GB9925127D0 (en) * 1999-10-22 1999-12-22 Pharmacia & Upjohn Spa Oral formulations for anti-tumor compounds
WO2001064202A2 (en) * 2000-03-01 2001-09-07 Euro-Celtique S.A. Tramadol for the treatment of functional gastrointestinal disorders
US7192612B2 (en) * 2001-02-22 2007-03-20 Purdue Research Foundation Compositions and methods based on synergies between capsicum extracts and tea catechins for prevention and treatment of cancer
WO2002067966A1 (en) 2001-02-22 2002-09-06 Purdue Research Foundation Compositions based on vanilloid-catechin synergies for prevention and treatment of cancer
US6428822B1 (en) 2001-04-03 2002-08-06 Chengzhi Life Science Company, Ltd. Extracts of mixed arctium lappa L., carrot and whole radish for treating hypertension, constipation and detoxification
US6682759B2 (en) * 2002-02-01 2004-01-27 Depomed, Inc. Manufacture of oral dosage forms delivering both immediate-release and sustained-release drugs
US7198804B2 (en) * 2002-04-12 2007-04-03 Helixir Co., Ltd. Crude drug composition for preventing and treating gastrointestinal dyskinetic diseases
JP2006514109A (ja) * 2002-12-18 2006-04-27 アルゴルクス ファーマスーティカルズ,インク カプサイシノイドの投与
PT1605956E (pt) 2002-12-18 2016-03-09 Centrexion Therapeutics Corp Administração de capsaicinóides para o tratamento da osteoartrite
CA2521925A1 (en) * 2003-04-08 2004-10-28 Algorx Pharmaceuticals, Inc. Preparation and purification of synthetic capsaicin
US20100159000A1 (en) * 2003-11-10 2010-06-24 Lundeen Sr James E Medicine for treating gastrointestinal disorder including fecal incontinence
AT413646B (de) * 2004-04-02 2006-04-15 Hammer Johann Dr Verwendung von capsaicin und/oder capsaicinoiden
US20050277657A1 (en) * 2004-06-15 2005-12-15 Dusan Ninkov Method of protection of biologically active essential oils and pharmaceutical composition for weight control and enhance fat burning in adults, adolescents and children
CA2596194A1 (en) * 2004-11-24 2006-06-01 Algorx Pharmaceuticals, Inc. Capsaicinoid gel formulation and uses thereof
US20080139641A1 (en) 2004-12-28 2008-06-12 Mestex Ag Use Of Resiniferatoxin (Rtx) For Producing An Agent For Treating Joint Pains And Method For Applying Said Agent
US20080103102A1 (en) 2006-10-27 2008-05-01 Bmb Patent Holding Corporation Therapeutic compositions and methods of treatment with capsianoside-type compounds
CN101835500B (zh) * 2007-08-29 2014-05-28 吸附剂治疗学公司 具有可变抗衡离子含量的吸收性聚合物组合物及其制备方法和用途
KR20090047637A (ko) * 2007-11-08 2009-05-13 재단법인서울대학교산학협력재단 커큐민 또는 이의 약학적으로 허용가능한 염을유효성분으로 함유하는 통증 예방 및 치료용 조성물
HUP0700755A2 (en) * 2007-11-26 2009-08-28 Pannonpharma Gyogyszergyar Pharmaceutical compositions containing capsaicionoid and non-steroidal anti-inflammatory drug
WO2010011597A2 (en) * 2008-07-22 2010-01-28 Mayo Foundation For Medical Education And Research Treatment of obesity and related disorders
US20110200669A1 (en) * 2010-02-15 2011-08-18 Winston Laboratories, Inc. Method and compositions of civamide to treat disease of the intestines
KR101378973B1 (ko) * 2012-04-13 2014-03-28 한미약품 주식회사 구형에 가까운 형태의 다중 투여 단위 정제를 포함하는 경질 캡슐 복합 제형 및 이의 제조방법
CN103027901B (zh) * 2012-12-11 2014-11-12 广东药学院 一种载辣椒素壳聚糖微球肠溶片及其制备方法
US10092528B2 (en) 2013-03-13 2018-10-09 Altria Client Services Llc Application of encapsulated capsaicin and analogues thereof for controlling calorie intake
US9289418B2 (en) 2013-03-15 2016-03-22 Cedars-Sinai Medical Center Methods of diagnosis, selection, and treatment of diseases and conditions caused by or associated with methanogens
EP2967060A4 (en) 2013-03-15 2016-11-23 Cedars Sinai Medical Center METHODS OF DIAGNOSING, SELECTING AND TREATING DISEASES AND CONDITIONS CAUSED BY OR ASSOCIATED WITH METHANOGENIC BACTERIA
AU2014380905A1 (en) 2014-01-30 2016-09-08 Omniactive Health Technologies Limited Composition of oily, pungent and odoriferous substances and a process of preparation thereof
WO2016025762A1 (en) 2014-08-13 2016-02-18 Cedars-Sinai Medical Center Anti-methanogenic compositions and uses thereof
US10736871B2 (en) 2015-04-01 2020-08-11 Cedars-Sinai Medical Center Anti-methanogenic lovastatin analogs or derivatives and uses thereof
AU2019457560A1 (en) * 2019-07-18 2022-02-17 Dignify Therapeutics, Llc Compositions and methods for inducing defecation
MX2022012920A (es) * 2020-04-15 2022-11-16 Gruenenthal Gmbh Composiciones de resiniferatoxina.
JP2024505139A (ja) * 2021-01-15 2024-02-05 ディグニファイ セラピューティクス エルエルシー 排便を誘発するための組成物及び方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2207705A1 (en) * 1972-11-24 1974-06-21 Marconnet Rene Deodorisation of body odours - by liberation of odoriferous substances in the intestines
EP0015334B1 (en) 1977-08-04 1982-05-19 J.B. Tillott Limited Carminative preparations containing peppermint oil or its active components
US4681897A (en) * 1984-01-16 1987-07-21 The Procter & Gamble Company Pharmaceutical products providing enhanced analgesia
US5403868A (en) 1988-12-23 1995-04-04 Sandoz Ltd. Capsaicin derivatives
HU206082B (en) * 1988-12-23 1992-08-28 Sandoz Ag Process for producing capsaicin derivatives and pharmaceutical compositions comprising such compounds
US5063060A (en) 1989-12-19 1991-11-05 Cisco Limited Partnership Compositions and method for treating painful, inflammatory or allergic disorders
DE4137540A1 (de) * 1991-11-14 1993-05-19 Steigerwald Arzneimittelwerk Verwendung von praeparaten der curcuma-pflanzen
US5431914A (en) 1992-04-17 1995-07-11 Adekunle; Michael Method of treating an internal condition by external application of capsaicin without the need for systemic absorption
CA2136174A1 (en) 1992-05-21 1993-11-25 Jeff J. Staggs Therapeutic uses of pungent botanicals and their related compounds
US5762963A (en) 1995-06-07 1998-06-09 Emory University Method and compositions for controlling oral and pharyngeal pain using capsaicinoids
WO1997003674A1 (en) 1995-07-14 1997-02-06 Sabinsa Corporation Bioprotectant composition, method of use and extraction process of curcuminoids

Also Published As

Publication number Publication date
GB2332147A (en) 1999-06-16
JP2002513418A (ja) 2002-05-08
ATE262892T1 (de) 2004-04-15
EP0988028A1 (en) 2000-03-29
AU7782998A (en) 1998-12-30
KR20010013618A (ko) 2001-02-26
CN1198594C (zh) 2005-04-27
ID22878A (id) 1999-12-16
CA2291796C (en) 2008-03-25
AR012960A1 (es) 2000-11-22
GB9811819D0 (en) 1998-07-29
US6201014B1 (en) 2001-03-13
DE69822822T2 (de) 2005-01-13
GB2332147B (en) 1999-10-27
BR9809994A (pt) 2000-08-01
PL337337A1 (en) 2000-08-14
ZA984920B (en) 1999-07-01
CA2291796A1 (en) 1998-12-17
EP0988028B1 (en) 2004-03-31
GB9827192D0 (en) 1999-02-03
GB9711962D0 (en) 1997-08-06
CN1259863A (zh) 2000-07-12
AU737606B2 (en) 2001-08-23
WO1998056356A1 (en) 1998-12-17
DE69822822D1 (de) 2004-05-06

Similar Documents

Publication Publication Date Title
HUP0004245A2 (hu) Terápiásan hatékony készítmények
NZ288298A (en) Hydroxamic acid and carboxylic acid derivatives; medicaments containing such derivatives that are metalloproteinase inhibitors
ATE261301T1 (de) Arzneizubereitungen enthaltend nicht-steroidale entzündungshemmende arzneimittel
WO1995031985A3 (en) Pharmaceutical compositions comprising an opiate antagonist and calcium salts, their use for the treatment of endorphin-mediated pathologies
MX9500885A (es) Preparacion farmaceutica para administracion oral.
IS4146A (is) Lyfjablanda til að gefa dýrum um munn sem inniheldur prótonupumpublokkara
HUP0302131A2 (hu) Gyógyászati tramadolsók, ezeket tartalmazó gyógyszerkészítmények
MY129350A (en) Aripiprazole oral solution
HUP0201489A2 (hu) Új adagolási forma
TR199800902T2 (xx) Ecza form�lasyonlar�.
HUP0004625A1 (hu) Az emésztőcsatorna felső szakaszának fokozott biztonságot nyújtó filmbevonatos tabletta
RU94027563A (ru) Соединения-ингибиторы вич протеазы, их использование для лечения спида, форикомпозиция
SE9700885D0 (sv) New pharmaceutical formulation
EP0244083A3 (en) Amino acid derivatives
HUP0105481A2 (hu) Klaritromicint vagy származékait tartalmazó gyógyászati készítmények és eljárás előállításukra, valamint alkalmazásuk
HUP0001104A2 (hu) Ibuprofent és domperidont tartalmazó készítmények migrén kezelésére
YU13599A (sh) Primena farmaceutske kompozicije za dobijanje leka u obliku gela
MX9709453A (es) Composicion farmaceutica oral de compuestos de piperidinoalcanol en forma de solucion.
HUP0004461A2 (hu) Apoliprotein B kiválasztást/mikroszomális trigliceridtranszfer-proteint gátló anyag alkalmazása gyógyászati készítmények előállítására és a fenti gyógyászati készítmények
RU93004785A (ru) Твердые капсулы окфосфата цитарабина
GB9420748D0 (en) 1,5 benzodiazepine derivatives
HUP9800623A2 (hu) (+)-O-demetil-tramadol felhasználása fájdalomcsillapító hatású orális gyógyszerkészítmények előállítására
NO326141B1 (no) Fremgangsmate for behandling av isolert systolisk hypertensjon
IT1265224B1 (it) Composizioni farmaceutiche per uso orale per il trattamento delle manifestazioni ulcerose gastro-duodenali ed esofagee
TH46047A (th) สารผสมซีลีคอกซิบ (celcecoxib)