HUE064111T2 - Gyógyhatású vegyületek - Google Patents

Gyógyhatású vegyületek

Info

Publication number
HUE064111T2
HUE064111T2 HUE19795615A HUE19795615A HUE064111T2 HU E064111 T2 HUE064111 T2 HU E064111T2 HU E19795615 A HUE19795615 A HU E19795615A HU E19795615 A HUE19795615 A HU E19795615A HU E064111 T2 HUE064111 T2 HU E064111T2
Authority
HU
Hungary
Prior art keywords
therapeutic compounds
therapeutic
compounds
Prior art date
Application number
HUE19795615A
Other languages
English (en)
Inventor
Emma Louise Blaney
Duncan James Crick
Simon Ross Crumpler
George Hynd
Cathy Louise Lucas
Barrie Phillip Martin
Nick Charles Ray
Eileen Mary Seward
David Gareth Evans
Bozec Lucille Le
Thorsten Nowak
Michael Geoffrey Neil Russell
Siew Kuen Yeap
Fabien Jean Ghislain Roussel
Sanjeet Singh Sehmi
Original Assignee
C4X Discovery Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB1817193.4A external-priority patent/GB201817193D0/en
Priority claimed from GBGB1907674.4A external-priority patent/GB201907674D0/en
Application filed by C4X Discovery Ltd filed Critical C4X Discovery Ltd
Publication of HUE064111T2 publication Critical patent/HUE064111T2/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/472Non-condensed isoquinolines, e.g. papaverine
    • A61K31/4725Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HUE19795615A 2018-10-22 2019-10-22 Gyógyhatású vegyületek HUE064111T2 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB1817193.4A GB201817193D0 (en) 2018-10-22 2018-10-22 Tetrahydroisoquinoline compounds
GBGB1907674.4A GB201907674D0 (en) 2019-05-30 2019-05-30 Tetrahydroisoquinoline compounds

Publications (1)

Publication Number Publication Date
HUE064111T2 true HUE064111T2 (hu) 2024-02-28

Family

ID=68393021

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE19795615A HUE064111T2 (hu) 2018-10-22 2019-10-22 Gyógyhatású vegyületek

Country Status (23)

Country Link
US (1) US20220002286A1 (hu)
EP (2) EP4252755A3 (hu)
JP (1) JP2022514437A (hu)
KR (1) KR20210080474A (hu)
CN (1) CN112996785A (hu)
AU (1) AU2019364717B2 (hu)
BR (1) BR112021007513A2 (hu)
CA (1) CA3114859A1 (hu)
DK (1) DK3870578T3 (hu)
ES (1) ES2963613T3 (hu)
FI (1) FI3870578T3 (hu)
HR (1) HRP20231306T1 (hu)
HU (1) HUE064111T2 (hu)
IL (1) IL282330A (hu)
LT (1) LT3870578T (hu)
MX (1) MX2021004566A (hu)
PH (1) PH12021550872A1 (hu)
PL (1) PL3870578T3 (hu)
PT (1) PT3870578T (hu)
RS (1) RS64836B1 (hu)
SG (1) SG11202103253YA (hu)
SI (1) SI3870578T1 (hu)
WO (1) WO2020084300A1 (hu)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4364804A2 (en) 2018-08-20 2024-05-08 Janssen Pharmaceutica NV Inhibitors of keap1-nrf2 protein-protein interaction
GB202005863D0 (en) * 2020-04-22 2020-06-03 C4X Discovery Ltd Therapeutic compounds
GB202005852D0 (en) * 2020-04-22 2020-06-03 C4X Discovery Ltd Therapeutic compounds
CN114507181B (zh) * 2020-11-17 2024-03-26 中国医学科学院药物研究所 含5-取代四氢异喹啉的丙酸类化合物、其药物组合物和应用
WO2023073364A1 (en) 2021-10-25 2023-05-04 C4X Discovery Limited Tetrahydroisoquinoline compounds that are keap1 binders
AR128216A1 (es) * 2022-01-07 2024-04-10 Chugai Pharmaceutical Co Ltd Compuesto heterocíclico que contiene nitrógeno que tiene un efecto de activación del nrf2

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2899183B1 (en) * 2011-10-14 2018-09-19 Bristol-Myers Squibb Company Substituted Tetrahydroisoquinoline Compounds as Factor Xia Inhibitors
GB202005863D0 (en) * 2020-04-22 2020-06-03 C4X Discovery Ltd Therapeutic compounds
GB202005852D0 (en) * 2020-04-22 2020-06-03 C4X Discovery Ltd Therapeutic compounds

Also Published As

Publication number Publication date
JP2022514437A (ja) 2022-02-10
PH12021550872A1 (en) 2021-12-06
EP4252755A3 (en) 2023-11-08
WO2020084300A1 (en) 2020-04-30
BR112021007513A2 (pt) 2021-07-27
LT3870578T (lt) 2023-12-11
PT3870578T (pt) 2023-11-15
DK3870578T3 (da) 2023-11-13
PL3870578T3 (pl) 2024-03-04
HRP20231306T1 (hr) 2024-02-02
AU2019364717A1 (en) 2021-06-03
EP3870578A1 (en) 2021-09-01
SG11202103253YA (en) 2021-05-28
CA3114859A1 (en) 2020-04-30
US20220002286A1 (en) 2022-01-06
CN112996785A (zh) 2021-06-18
ES2963613T3 (es) 2024-04-01
AU2019364717B2 (en) 2023-07-20
SI3870578T1 (sl) 2024-02-29
IL282330A (en) 2021-05-31
EP3870578B1 (en) 2023-08-16
RS64836B1 (sr) 2023-12-29
EP4252755A2 (en) 2023-10-04
MX2021004566A (es) 2021-06-08
KR20210080474A (ko) 2021-06-30
FI3870578T3 (fi) 2023-11-03

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