HUE057858T2 - Humán komplement faktor C2B-t megkötõ kötõ molekulák és alkalmazásaik - Google Patents

Humán komplement faktor C2B-t megkötõ kötõ molekulák és alkalmazásaik

Info

Publication number
HUE057858T2
HUE057858T2 HUE20165165A HUE20165165A HUE057858T2 HU E057858 T2 HUE057858 T2 HU E057858T2 HU E20165165 A HUE20165165 A HU E20165165A HU E20165165 A HUE20165165 A HU E20165165A HU E057858 T2 HUE057858 T2 HU E057858T2
Authority
HU
Hungary
Prior art keywords
binding molecules
complement factor
human complement
bind human
bind
Prior art date
Application number
HUE20165165A
Other languages
English (en)
Hungarian (hu)
Inventor
Cornelis Erik Hack
Cafer Yildiz
Louis Boon
Petrus Johannes Simons
Original Assignee
Broteio Pharma B V
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Broteio Pharma B V filed Critical Broteio Pharma B V
Publication of HUE057858T2 publication Critical patent/HUE057858T2/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Transplantation (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Cardiology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
HUE20165165A 2013-05-23 2014-05-22 Humán komplement faktor C2B-t megkötõ kötõ molekulák és alkalmazásaik HUE057858T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP13168941 2013-05-23

Publications (1)

Publication Number Publication Date
HUE057858T2 true HUE057858T2 (hu) 2022-06-28

Family

ID=48485015

Family Applications (2)

Application Number Title Priority Date Filing Date
HUE20165165A HUE057858T2 (hu) 2013-05-23 2014-05-22 Humán komplement faktor C2B-t megkötõ kötõ molekulák és alkalmazásaik
HUE14729463A HUE049769T2 (hu) 2013-05-23 2014-05-22 Humán komplemens C2 faktort kötõ kötõ molekulák és alkalmazásaik

Family Applications After (1)

Application Number Title Priority Date Filing Date
HUE14729463A HUE049769T2 (hu) 2013-05-23 2014-05-22 Humán komplemens C2 faktort kötõ kötõ molekulák és alkalmazásaik

Country Status (14)

Country Link
US (2) US9944717B2 (enExample)
EP (2) EP2999714B1 (enExample)
JP (3) JP2016520313A (enExample)
CN (1) CN105492461B (enExample)
AU (1) AU2014269193C1 (enExample)
CA (1) CA2913318C (enExample)
DK (2) DK2999714T3 (enExample)
ES (2) ES2784616T3 (enExample)
HU (2) HUE057858T2 (enExample)
LT (2) LT2999714T (enExample)
MX (1) MX366046B (enExample)
PL (2) PL2999714T3 (enExample)
PT (2) PT2999714T (enExample)
WO (1) WO2014189378A1 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8945562B2 (en) 2012-11-02 2015-02-03 True North Therapeutics, Inc. Anti-complement C1s antibodies
LT2999714T (lt) * 2013-05-23 2020-07-10 Broteio Pharma B.V. Surišančios molekulės, kurios suriša žmogaus komplemento faktorių c2 ir jų panaudojimas
PE20191031A1 (es) 2016-10-12 2019-08-05 Bioverativ Usa Inc ANTICUERPOS ANTI-C1s Y METODOS DE USO DE LOS MISMOS
US11161900B2 (en) * 2018-12-13 2021-11-02 Argenx Bvba Antibodies that specifically bind to human complement factor C2b
GB2584105B (en) * 2019-05-21 2023-08-02 Argenx Bvba Methods of treating neuropathy
EP4013785A4 (en) * 2019-08-12 2023-12-20 CSL Innovation Pty Ltd COMPLEMENT C2 BINDING PROTEINS AND THEIR USES
US20250376539A1 (en) * 2022-01-29 2025-12-11 Kira Pharmaceuticals (Suzhou) Ltd. Anti-c2 antibodies and uses thereof
GB202407051D0 (en) 2024-05-17 2024-07-03 argenx BV Methods of treating osteoarthritis pain
WO2025257157A1 (en) 2024-06-10 2025-12-18 argenx BV Treatment or prevention of ischemia reperfusion injury in organ tranplantation

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
ES2329010T3 (es) * 2000-03-23 2009-11-20 Genentech, Inc. Inhibidores anti-c2/c2a de la activacion del complemento.
LT2999714T (lt) * 2013-05-23 2020-07-10 Broteio Pharma B.V. Surišančios molekulės, kurios suriša žmogaus komplemento faktorių c2 ir jų panaudojimas

Also Published As

Publication number Publication date
CA2913318C (en) 2024-03-26
PL2999714T3 (pl) 2020-10-19
JP7163254B2 (ja) 2022-10-31
US10717785B2 (en) 2020-07-21
LT2999714T (lt) 2020-07-10
EP2999714A1 (en) 2016-03-30
PT2999714T (pt) 2020-04-30
DK2999714T3 (da) 2020-06-02
LT3725803T (lt) 2022-03-10
ES2904709T3 (es) 2022-04-05
EP3725803B1 (en) 2021-12-15
JP7414929B2 (ja) 2024-01-16
PT3725803T (pt) 2021-12-24
JP2020007318A (ja) 2020-01-16
EP3725803A1 (en) 2020-10-21
AU2014269193B2 (en) 2019-08-15
AU2014269193A1 (en) 2015-12-17
AU2014269193C1 (en) 2020-02-20
EP2999714B1 (en) 2020-04-01
US9944717B2 (en) 2018-04-17
WO2014189378A1 (en) 2014-11-27
CA2913318A1 (en) 2014-11-27
US20160108134A1 (en) 2016-04-21
JP2016520313A (ja) 2016-07-14
CN105492461A (zh) 2016-04-13
HK1223385A1 (zh) 2017-07-28
MX366046B (es) 2019-06-26
ES2784616T3 (es) 2020-09-29
MX2015016120A (es) 2016-10-28
DK3725803T3 (da) 2022-03-07
CN105492461B (zh) 2019-11-26
JP2023002684A (ja) 2023-01-10
US20180319895A1 (en) 2018-11-08
HUE049769T2 (hu) 2020-10-28
PL3725803T3 (pl) 2022-04-04

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