HUE052634T2 - Adalékrendszerek felhasználásra protein pegilálásban - Google Patents

Adalékrendszerek felhasználásra protein pegilálásban

Info

Publication number
HUE052634T2
HUE052634T2 HUE16816042A HUE16816042A HUE052634T2 HU E052634 T2 HUE052634 T2 HU E052634T2 HU E16816042 A HUE16816042 A HU E16816042A HU E16816042 A HUE16816042 A HU E16816042A HU E052634 T2 HUE052634 T2 HU E052634T2
Authority
HU
Hungary
Prior art keywords
additive systems
protein pegylation
pegylation
protein
additive
Prior art date
Application number
HUE16816042A
Other languages
English (en)
Hungarian (hu)
Inventor
Matthew R Hickey
Antonio Ramirez
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of HUE052634T2 publication Critical patent/HUE052634T2/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/50Fibroblast growth factor [FGF]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/64Relaxins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HUE16816042A 2015-11-23 2016-11-22 Adalékrendszerek felhasználásra protein pegilálásban HUE052634T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201562258644P 2015-11-23 2015-11-23

Publications (1)

Publication Number Publication Date
HUE052634T2 true HUE052634T2 (hu) 2021-05-28

Family

ID=57589163

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE16816042A HUE052634T2 (hu) 2015-11-23 2016-11-22 Adalékrendszerek felhasználásra protein pegilálásban

Country Status (17)

Country Link
US (3) US10617765B2 (enExample)
EP (2) EP3789395B1 (enExample)
JP (2) JP6921821B2 (enExample)
KR (1) KR102688003B1 (enExample)
CN (2) CN108350025B (enExample)
CY (1) CY1123699T1 (enExample)
DK (1) DK3380487T3 (enExample)
ES (1) ES2827776T3 (enExample)
HR (1) HRP20201832T1 (enExample)
HU (1) HUE052634T2 (enExample)
LT (1) LT3380487T (enExample)
PL (1) PL3380487T3 (enExample)
PT (1) PT3380487T (enExample)
RS (1) RS61072B1 (enExample)
SI (1) SI3380487T1 (enExample)
SM (1) SMT202000649T1 (enExample)
WO (1) WO2017091568A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017091568A1 (en) * 2015-11-23 2017-06-01 Bristol-Myers Squibb Company Additive systems for use in protein pegylation
LT3849614T (lt) * 2018-09-11 2024-03-25 Ambrx, Inc. Interleukino-2 polipeptido konjugatai ir jų panaudojimas
CN111484551B (zh) * 2020-03-19 2022-02-11 北京翼方生物科技有限责任公司 一种聚乙二醇修饰的重组人碱性成纤维细胞生长因子

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19535571A1 (de) 1995-09-14 1997-03-20 Boehringer Mannheim Gmbh Pharmazeutische Kombinationspräparate und deren Verwendung zur Behandlung von Hämodialysepatienten
TWI240627B (en) 1996-04-26 2005-10-01 Chugai Pharmaceutical Co Ltd Erythropoietin solution preparation
EP0885613A1 (de) 1997-06-21 1998-12-23 Roche Diagnostics GmbH Verwendung von modifizierten Hämoglobinen zur Behandlung von Anämien und Kombinationspräparate umfassend Erythropoietin und modifiziertes Hämoglobin
DE19734293A1 (de) 1997-08-08 1999-02-11 Boehringer Mannheim Gmbh Verwendung von pharmazeutischen Kombinationspräparaten enthaltend Erythropoietin und Eisenpräparate zur Behandlung von rheumatischen Erkrankungen
JP5460958B2 (ja) * 2004-03-17 2014-04-02 アンチキャンサー インコーポレーテッド タンパク質ポリエチレングリコール(peg)複合体形成を増大させる方法
TW200722521A (en) * 2005-06-01 2007-06-16 Alza Corp Novel bioconjugation reactions for acylating polyethylene glycol reagents
JP5508716B2 (ja) * 2005-11-08 2014-06-04 アンブルックス,インコーポレイテッド 非天然アミノ酸、および非天然アミノ酸ポリペプチドを修飾するための促進剤
ES2385114T3 (es) * 2007-03-30 2012-07-18 Ambrx, Inc. Polipéptidos de FGF-21 modificados y sus usos
CA2899448C (en) 2013-01-30 2021-10-26 Avelas Biosciences, Inc. Selective delivery molecules and methods of use
HK1222122A1 (zh) 2013-04-22 2017-06-23 Avelas Biosciences, Inc. 选择性药物递送组合物及使用方法
SG11201702824UA (en) 2014-10-24 2017-05-30 Bristol Myers Squibb Co Modified fgf-21 polypeptides and uses thereof
WO2017091568A1 (en) * 2015-11-23 2017-06-01 Bristol-Myers Squibb Company Additive systems for use in protein pegylation

Also Published As

Publication number Publication date
US20220160883A1 (en) 2022-05-26
US10617765B2 (en) 2020-04-14
JP2021176890A (ja) 2021-11-11
US20200276319A1 (en) 2020-09-03
EP3789395B1 (en) 2025-08-27
CY1123699T1 (el) 2022-03-24
HRP20201832T1 (hr) 2021-01-08
ES2827776T3 (es) 2021-05-24
US11213589B2 (en) 2022-01-04
DK3380487T3 (da) 2020-12-07
CN115819494A (zh) 2023-03-21
SI3380487T1 (sl) 2020-11-30
CN108350025B (zh) 2023-02-21
EP3789395A1 (en) 2021-03-10
US20190351065A1 (en) 2019-11-21
RS61072B1 (sr) 2020-12-31
JP2019503994A (ja) 2019-02-14
CN108350025A (zh) 2018-07-31
KR20180081610A (ko) 2018-07-16
JP7257457B2 (ja) 2023-04-13
SMT202000649T1 (it) 2021-01-05
LT3380487T (lt) 2020-12-28
EP3380487A1 (en) 2018-10-03
KR102688003B1 (ko) 2024-07-23
PT3380487T (pt) 2020-10-29
PL3380487T3 (pl) 2020-12-28
WO2017091568A8 (en) 2018-01-04
JP6921821B2 (ja) 2021-08-18
WO2017091568A1 (en) 2017-06-01
EP3380487B1 (en) 2020-09-02

Similar Documents

Publication Publication Date Title
IL254516B (en) Proteins specific for cd137
IL256867B (en) Calibration techniques in haptic systems
DK3197453T3 (da) Kimært protein
IL248770A0 (en) A trading system
DK3182985T3 (da) Fibroinafledt proteinsammensætning
CL2015003759S1 (es) Transportador
LT3386954T (lt) Dimeriniai kontrastiniai agentai
DK3325514T3 (da) Her2-bindende proteiner baseret på di-ubiquitin-muteiner
EP3345473A4 (en) HARVESTER
EP3355931C0 (en) PROTEIN CONJUGATES
EP3344595A4 (en) BLASTING AGENT
EP3351087A4 (en) HARVESTER
DK3702450T3 (da) Protein
DK3364753T3 (da) Blandevogn
EP3328438A4 (en) POLYPEPTIDE MONOLITH
EP3392982A4 (en) INTERCONNECTS
EP3315831A4 (en) sliding component
EP3392981A4 (en) INTERCONNECTS
DK3132031T3 (da) Carbohydratbindende protein
HRP20182029T1 (hr) Uti-fuzijski proteini
EP3272204A4 (en) HARVESTER
DK3099793T3 (da) Protein
EP2986625A4 (en) MIXED MODE LIGANDS
PL3297622T3 (pl) Kombinacje oksykodonu i n-acyloetanoloaminy palmitoiloetanoloaminy do zmniejszenia skutków ubocznych związanych z opioidami
HUE052634T2 (hu) Adalékrendszerek felhasználásra protein pegilálásban