HUE047044T2 - Piperazin-származékok és gyógyszerként történõ alkalmazásuk - Google Patents

Piperazin-származékok és gyógyszerként történõ alkalmazásuk

Info

Publication number
HUE047044T2
HUE047044T2 HUE14784235A HUE14784235A HUE047044T2 HU E047044 T2 HUE047044 T2 HU E047044T2 HU E14784235 A HUE14784235 A HU E14784235A HU E14784235 A HUE14784235 A HU E14784235A HU E047044 T2 HUE047044 T2 HU E047044T2
Authority
HU
Hungary
Prior art keywords
medicament
piperazine derivatives
piperazine
derivatives
Prior art date
Application number
HUE14784235A
Other languages
English (en)
Inventor
Christoph Hoenke
Riccardo Giovannini
Uta Lessel
Holger Rosenbrock
Bernhard Schmid
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of HUE047044T2 publication Critical patent/HUE047044T2/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
HUE14784235A 2013-10-16 2014-10-15 Piperazin-származékok és gyógyszerként történõ alkalmazásuk HUE047044T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP13188904 2013-10-16

Publications (1)

Publication Number Publication Date
HUE047044T2 true HUE047044T2 (hu) 2020-04-28

Family

ID=49354583

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE14784235A HUE047044T2 (hu) 2013-10-16 2014-10-15 Piperazin-származékok és gyógyszerként történõ alkalmazásuk

Country Status (21)

Country Link
US (1) US9233953B2 (hu)
EP (1) EP3057963B1 (hu)
JP (1) JP6483105B2 (hu)
KR (1) KR102281284B1 (hu)
CN (1) CN105636961B (hu)
AR (1) AR098037A1 (hu)
AU (1) AU2014336258B2 (hu)
BR (1) BR112016008062B1 (hu)
CA (1) CA2926754C (hu)
CL (1) CL2016000884A1 (hu)
DK (1) DK3057963T3 (hu)
EA (1) EA029313B1 (hu)
ES (1) ES2745555T3 (hu)
HU (1) HUE047044T2 (hu)
IL (1) IL244693B (hu)
MX (1) MX370006B (hu)
PH (1) PH12016500577A1 (hu)
PL (1) PL3057963T3 (hu)
TW (1) TW201609716A (hu)
UY (1) UY35785A (hu)
WO (1) WO2015055698A1 (hu)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106854189A (zh) * 2015-12-08 2017-06-16 湖南华腾制药有限公司 一种哌嗪化合物的合成方法
CN107778257A (zh) * 2016-08-29 2018-03-09 湖南华腾制药有限公司 一种哌嗪衍生物的合成方法
CN106977463A (zh) * 2017-05-31 2017-07-25 湖南华腾制药有限公司 一种联苯取代哌嗪衍生物的合成方法
CN107417679A (zh) * 2017-08-04 2017-12-01 河南农业大学 1,3‑唑类取代吡嗪类化合物的制备方法
JP2023509792A (ja) 2020-01-09 2023-03-09 ディスク・メディシン・インコーポレイテッド グリシン輸送阻害剤を用いて骨髄性プロトポルフィリン症、x連鎖プロトポルフィリン症または先天性赤血球生成性ポルフィリン症を処置する方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0224084D0 (en) * 2002-10-16 2002-11-27 Glaxo Group Ltd Novel compounds
GB0505085D0 (en) * 2005-03-11 2005-04-20 Glaxo Group Ltd Compounds
WO2006113704A2 (en) 2005-04-18 2006-10-26 Neurogen Corporation Subtituted heteroaryl cb1 antagonists
CN102574857B (zh) 2009-07-08 2015-06-10 利奥制药有限公司 作为jak受体和蛋白酪氨酸激酶抑制剂的杂环化合物

Also Published As

Publication number Publication date
KR20160062187A (ko) 2016-06-01
BR112016008062B1 (pt) 2022-11-16
PH12016500577B1 (en) 2016-06-20
US20150105397A1 (en) 2015-04-16
WO2015055698A1 (en) 2015-04-23
JP2016533368A (ja) 2016-10-27
EA029313B1 (ru) 2018-03-30
BR112016008062A2 (hu) 2017-08-01
CA2926754C (en) 2021-09-14
NZ718251A (en) 2021-02-26
US9233953B2 (en) 2016-01-12
IL244693A0 (en) 2016-04-21
EP3057963B1 (en) 2019-06-19
TW201609716A (zh) 2016-03-16
MX2016004847A (es) 2016-07-19
KR102281284B1 (ko) 2021-07-23
PL3057963T3 (pl) 2019-12-31
EA201600323A1 (ru) 2016-10-31
MX370006B (es) 2019-11-28
AU2014336258B2 (en) 2018-07-12
PH12016500577A1 (en) 2016-06-20
UY35785A (es) 2015-04-30
CA2926754A1 (en) 2015-04-23
CN105636961B (zh) 2019-11-05
CL2016000884A1 (es) 2016-12-30
AR098037A1 (es) 2016-04-27
ES2745555T3 (es) 2020-03-02
IL244693B (en) 2019-08-29
DK3057963T3 (da) 2019-09-16
JP6483105B2 (ja) 2019-03-13
CN105636961A (zh) 2016-06-01
EP3057963A1 (en) 2016-08-24
AU2014336258A1 (en) 2016-04-14

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