HUE043767T2 - Alkilezõszerek stabilizált készítményei és alkalmazási eljárásaik - Google Patents

Alkilezõszerek stabilizált készítményei és alkalmazási eljárásaik

Info

Publication number
HUE043767T2
HUE043767T2 HUE09724939A HUE09724939A HUE043767T2 HU E043767 T2 HUE043767 T2 HU E043767T2 HU E09724939 A HUE09724939 A HU E09724939A HU E09724939 A HUE09724939 A HU E09724939A HU E043767 T2 HUE043767 T2 HU E043767T2
Authority
HU
Hungary
Prior art keywords
methods
same
alkylating agents
stabilized compositions
stabilized
Prior art date
Application number
HUE09724939A
Other languages
English (en)
Inventor
Robert Alonso
Barry Walker
Peter Crooks
Original Assignee
Helsinn Healthcare Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Helsinn Healthcare Sa filed Critical Helsinn Healthcare Sa
Publication of HUE043767T2 publication Critical patent/HUE043767T2/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/131—Amines acyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HUE09724939A 2008-03-27 2009-03-11 Alkilezõszerek stabilizált készítményei és alkalmazási eljárásaik HUE043767T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3984008P 2008-03-27 2008-03-27

Publications (1)

Publication Number Publication Date
HUE043767T2 true HUE043767T2 (hu) 2019-09-30

Family

ID=41114573

Family Applications (2)

Application Number Title Priority Date Filing Date
HUE09724939A HUE043767T2 (hu) 2008-03-27 2009-03-11 Alkilezõszerek stabilizált készítményei és alkalmazási eljárásaik
HUE18214529A HUE053482T2 (hu) 2008-03-27 2009-03-11 Alkilezõszerek stabilizált készítményei és alkalmazási eljárásaik

Family Applications After (1)

Application Number Title Priority Date Filing Date
HUE18214529A HUE053482T2 (hu) 2008-03-27 2009-03-11 Alkilezõszerek stabilizált készítményei és alkalmazási eljárásaik

Country Status (14)

Country Link
US (2) US8501817B2 (hu)
EP (2) EP3494960B1 (hu)
CN (2) CN107149591A (hu)
CY (2) CY1121777T1 (hu)
DK (1) DK3494960T3 (hu)
ES (2) ES2727523T3 (hu)
HR (2) HRP20190551T1 (hu)
HU (2) HUE043767T2 (hu)
LT (2) LT2273876T (hu)
PL (2) PL2273876T3 (hu)
PT (2) PT2273876T (hu)
SI (2) SI2273876T1 (hu)
TR (1) TR201907794T4 (hu)
WO (1) WO2009120493A2 (hu)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
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US8501818B2 (en) 2005-03-14 2013-08-06 Ceptaris Therapeutics, Inc. Stabilized compositions of alkylating agents and methods of using same
US20110039943A1 (en) * 2005-03-14 2011-02-17 Robert Alonso Methods for treating skin disorders with topical nitrogen mustard compositions
US7872050B2 (en) * 2005-03-14 2011-01-18 Yaupon Therapeutics Inc. Stabilized compositions of volatile alkylating agents and methods of using thereof
ES2727523T3 (es) * 2008-03-27 2019-10-16 Helsinn Healthcare Sa Composiciones estabilizadas de agentes de alquilación y métodos de utilización de estas composiciones
US20180125797A1 (en) * 2016-11-07 2018-05-10 Actelion Pharmaceuticals Ltd Methods for treating skin disorders with a topical composition of bis-(2-chloroethyl)methylamine

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US3904766A (en) 1973-06-19 1975-09-09 Scott Eugene J Van Treatment of psoriasis
US4206222A (en) * 1977-06-23 1980-06-03 Societe Civile Particuliere De Brevets Suffren Method for preparing a substance having properties against collagen diseases and products obtained
US5075108A (en) 1986-01-03 1991-12-24 Consolidated Pharmaceuticals, Limited Melphalan derivatives
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US4853388A (en) 1987-05-15 1989-08-01 Pearlman Dale L Method for treating psoriasis with cytotoxic agents
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US4888354A (en) * 1987-12-21 1989-12-19 Theratech, Inc. Skin penetration enhancement using free base and acid addition salt combinations of active agents
US5719197A (en) * 1988-03-04 1998-02-17 Noven Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
US4949641A (en) 1990-03-05 1990-08-21 The United States Of America As Represented By The Secretary Of The Army Method of safely detoxifying mustard gases
US6764681B2 (en) * 1991-10-07 2004-07-20 Biogen, Inc. Method of prophylaxis or treatment of antigen presenting cell driven skin conditions using inhibitors of the CD2/LFA-3 interaction
US5820872A (en) 1992-11-18 1998-10-13 Yale University Methods and compositions for improving the effectiveness of X-irradiation therapy for the treatment of an internal solid tumor
WO1995003028A1 (en) * 1993-07-23 1995-02-02 Morris Herstein Cosmetic, skin-renewal stimulating composition with long-term irritation control
FR2728166A1 (fr) * 1994-12-19 1996-06-21 Oreal Composition topique contenant un antagoniste de substance p
GB9501052D0 (en) * 1995-01-19 1995-03-08 Cancer Res Campaign Tech Improvements relating to prodrugs
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US5948437A (en) * 1996-05-23 1999-09-07 Zeneca Limited Pharmaceutical compositions using thiazepine
DK0923941T3 (da) 1996-06-27 2006-09-18 Chugai Pharmaceutical Co Ltd Midler mod myelom der skal anvendes sammen med nitrogensennepantitumormidler
BR9710289A (pt) * 1996-07-11 1999-08-17 Farmarc Nederland Bv Composi-Æo farmac-utica contendo sal cido de adi-Æo de medicamento b sico
US6753155B1 (en) 1997-05-13 2004-06-22 The United States Of America As Represented By The Secretary Of The Army Protein biomarker for mustard chemical injury
WO1999001118A2 (en) * 1997-07-01 1999-01-14 Atherogenics, Inc. Antioxidant enhancement of therapy for hyperproliferative conditions
JP2003518359A (ja) * 1998-01-30 2003-06-10 コールド スプリング ハーバー ラボラトリー 細胞増殖の調節、方法および試薬
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US20070287719A1 (en) * 2005-03-11 2007-12-13 Pfizer Inc Salts, Prodrugs and Formulations of 1-[5-(4-Amino-7-Isopropyl-7H-Pyrrolo[2,3-D]Pyrimidine-5-Carbonyl)-2-Methoxy-Phenyl]-3-(2,4-Dichloro-Phenyl)-Urea
US20110039943A1 (en) * 2005-03-14 2011-02-17 Robert Alonso Methods for treating skin disorders with topical nitrogen mustard compositions
US7872050B2 (en) 2005-03-14 2011-01-18 Yaupon Therapeutics Inc. Stabilized compositions of volatile alkylating agents and methods of using thereof
US20060281720A1 (en) * 2005-06-08 2006-12-14 Loria Roger M 5-Androstenediol As An Inhibitor of Gliomas
ES2727523T3 (es) 2008-03-27 2019-10-16 Helsinn Healthcare Sa Composiciones estabilizadas de agentes de alquilación y métodos de utilización de estas composiciones

Also Published As

Publication number Publication date
WO2009120493A3 (en) 2010-03-04
TR201907794T4 (tr) 2019-06-21
EP2273876B1 (en) 2019-03-06
EP3494960A1 (en) 2019-06-12
PL2273876T3 (pl) 2019-09-30
HRP20210283T1 (hr) 2021-04-02
EP2273876A2 (en) 2011-01-19
LT2273876T (lt) 2019-05-27
CY1123974T1 (el) 2022-05-27
LT3494960T (lt) 2021-02-25
US8501817B2 (en) 2013-08-06
HRP20190551T1 (hr) 2019-05-03
US20100029783A9 (en) 2010-02-04
ES2727523T3 (es) 2019-10-16
EP2273876A4 (en) 2013-10-23
PT2273876T (pt) 2019-06-04
EP3494960B1 (en) 2020-11-25
CY1121777T1 (el) 2020-07-31
HUE053482T2 (hu) 2021-06-28
PT3494960T (pt) 2021-02-09
US20090247645A1 (en) 2009-10-01
CN107149591A (zh) 2017-09-12
DK3494960T3 (da) 2021-01-25
SI2273876T1 (sl) 2019-09-30
PL3494960T3 (pl) 2021-05-17
ES2848841T3 (es) 2021-08-12
CN102036557A (zh) 2011-04-27
WO2009120493A2 (en) 2009-10-01
SI3494960T1 (sl) 2021-04-30
US20140142193A1 (en) 2014-05-22

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