HU9300729D0 - Method for producing substituted pyrrholidine derivatives of hiv-protease inhibitor effect and medical preparatives containing them - Google Patents
Method for producing substituted pyrrholidine derivatives of hiv-protease inhibitor effect and medical preparatives containing themInfo
- Publication number
- HU9300729D0 HU9300729D0 HU9300729A HU9300729A HU9300729D0 HU 9300729 D0 HU9300729 D0 HU 9300729D0 HU 9300729 A HU9300729 A HU 9300729A HU 9300729 A HU9300729 A HU 9300729A HU 9300729 D0 HU9300729 D0 HU 9300729D0
- Authority
- HU
- Hungary
- Prior art keywords
- hiv
- pyrrholidine
- derivatives
- protease inhibitor
- inhibitor effect
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- AIDS & HIV (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Peptides Or Proteins (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US85059692A | 1992-03-13 | 1992-03-13 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| HU9300729D0 true HU9300729D0 (en) | 1993-05-28 |
| HUT70147A HUT70147A (en) | 1995-09-28 |
| HU215520B HU215520B (hu) | 1999-01-28 |
Family
ID=25308596
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9300729A HU215520B (hu) | 1992-03-13 | 1993-03-12 | Eljárás HIV-proteáz inhibitor hatású szubsztituált pirrolidinszármazékok és ezeket tartalmazó gyógyszerkészítmények előállítására |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5552405A (hu) |
| EP (1) | EP0560269B1 (hu) |
| JP (1) | JP3198191B2 (hu) |
| AT (1) | ATE123275T1 (hu) |
| AU (1) | AU663164B2 (hu) |
| CA (1) | CA2092653C (hu) |
| DE (1) | DE69300169T2 (hu) |
| HU (1) | HU215520B (hu) |
| NZ (1) | NZ247124A (hu) |
| PL (1) | PL173459B1 (hu) |
| TW (1) | TW301651B (hu) |
| ZA (1) | ZA931777B (hu) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2126794C1 (ru) | 1992-03-11 | 1999-02-27 | Нархекс Лимитед | Аминопроизводные оксо- или гидроксизамещенных гидразинов, способ их получения и фармацевтические композиции для ингибирования ретровирусной протеазы |
| DE69333270T2 (de) | 1992-03-11 | 2004-08-05 | Narhex Ltd. | Aminderivate von oxo- und hydroxy- substituierten kohlenwasserstoffen |
| US5888992A (en) | 1992-03-11 | 1999-03-30 | Narhex Limited | Polar substituted hydrocarbons |
| US6071895A (en) | 1992-03-11 | 2000-06-06 | Narhex Limited | Polar-substituted hydrocarbons |
| ES2066623T3 (es) * | 1992-03-13 | 1995-03-01 | Bio Mega Boehringer Ingelheim | Derivados sustituidos del acido pipecolinico como inhibidores de la vih-proteasa. |
| US5559256A (en) * | 1992-07-20 | 1996-09-24 | E. R. Squibb & Sons, Inc. | Aminediol protease inhibitors |
| EP0610745A3 (en) * | 1993-02-09 | 1994-09-28 | Miles Inc | Novel aminomethylene derivatives as immunosuppressants. |
| IL110898A0 (en) * | 1993-09-10 | 1994-11-28 | Narhex Australia Pty Ltd | Polar-substituted hydrocarbons |
| US5883252A (en) * | 1996-01-26 | 1999-03-16 | Vertex Pharmaceuticals Incorporated | Aspartyl protease inhibitors |
| EP1039886A4 (en) * | 1997-12-08 | 2001-05-16 | Scripps Research Inst | A SMALL P3 REMAINING HIV / FIV PROTEASE INHIBITOR |
| US6803466B1 (en) * | 1997-12-08 | 2004-10-12 | The Scripps Research Institute | HIV/FIV protease inhibitors having a small P3 residue |
| US6251906B1 (en) | 1998-05-15 | 2001-06-26 | Abbott Laboratories | Retroviral protease inhibiting compounds |
| US7087418B2 (en) | 2001-12-19 | 2006-08-08 | Bristol-Myers Squibb Company | Pichia pastoris formate dehydrogenase and uses therefor |
| US7662852B2 (en) | 2003-05-22 | 2010-02-16 | Lead Chemical Co., Ltd. | Compounds and preparations having antiviral effect |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1340588C (en) * | 1988-06-13 | 1999-06-08 | Balraj Krishan Handa | Amino acid derivatives |
| EP0361341A3 (en) * | 1988-09-28 | 1991-07-03 | Miles Inc. | Therapeutics for aids based on inhibitors of hiv protease |
| WO1991008221A1 (en) * | 1989-12-04 | 1991-06-13 | Wisconsin Alumni Research Foundation | Peptide inhibitors of hiv protease |
-
1993
- 1993-02-12 ZA ZA931777A patent/ZA931777B/xx unknown
- 1993-03-09 EP EP93103713A patent/EP0560269B1/en not_active Expired - Lifetime
- 1993-03-09 AT AT93103713T patent/ATE123275T1/de not_active IP Right Cessation
- 1993-03-09 DE DE69300169T patent/DE69300169T2/de not_active Expired - Lifetime
- 1993-03-11 NZ NZ247124A patent/NZ247124A/en unknown
- 1993-03-12 PL PL93298038A patent/PL173459B1/pl unknown
- 1993-03-12 AU AU35165/93A patent/AU663164B2/en not_active Ceased
- 1993-03-12 CA CA002092653A patent/CA2092653C/en not_active Expired - Lifetime
- 1993-03-12 HU HU9300729A patent/HU215520B/hu not_active IP Right Cessation
- 1993-03-15 JP JP05414193A patent/JP3198191B2/ja not_active Expired - Fee Related
- 1993-03-23 TW TW082102142A patent/TW301651B/zh active
-
1995
- 1995-07-31 US US08/509,268 patent/US5552405A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| PL173459B1 (pl) | 1998-03-31 |
| JP3198191B2 (ja) | 2001-08-13 |
| HU215520B (hu) | 1999-01-28 |
| HUT70147A (en) | 1995-09-28 |
| DE69300169T2 (de) | 1995-10-26 |
| TW301651B (hu) | 1997-04-01 |
| ZA931777B (en) | 1993-09-23 |
| AU663164B2 (en) | 1995-09-28 |
| EP0560269B1 (en) | 1995-05-31 |
| US5552405A (en) | 1996-09-03 |
| AU3516593A (en) | 1993-09-16 |
| PL298038A1 (en) | 1993-11-15 |
| EP0560269A1 (en) | 1993-09-15 |
| CA2092653A1 (en) | 1993-09-14 |
| DE69300169D1 (de) | 1995-07-06 |
| JPH0625158A (ja) | 1994-02-01 |
| CA2092653C (en) | 1998-12-15 |
| ATE123275T1 (de) | 1995-06-15 |
| NZ247124A (en) | 1995-09-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AU697681B2 (en) | Retroviral protease inhibiting compounds | |
| CA2131185A1 (en) | Substituted Pipecolinic Acid Derivatives as HIV Protease Inhibitors | |
| AU694417B2 (en) | Cyclic ureas and analogues useful as retroviral protease inhibitiors | |
| HU9300729D0 (en) | Method for producing substituted pyrrholidine derivatives of hiv-protease inhibitor effect and medical preparatives containing them | |
| FI860878A (fi) | Aminosyraderivat och foerfarande foer deras framstaellning. | |
| DK540589D0 (da) | Pyrrolidinderivater |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| DGB9 | Succession in title of applicant |
Owner name: BOEHRINGER INGELHEIM (CANADA) LTD., CA |
|
| HMM4 | Cancellation of final prot. due to non-payment of fee |