HU904131D0 - Process for producing heterocyclic diaryl ethers and pharmaceutical preparatives containing these compounds as active substance - Google Patents
Process for producing heterocyclic diaryl ethers and pharmaceutical preparatives containing these compounds as active substanceInfo
- Publication number
- HU904131D0 HU904131D0 HU904131A HU413190A HU904131D0 HU 904131 D0 HU904131 D0 HU 904131D0 HU 904131 A HU904131 A HU 904131A HU 413190 A HU413190 A HU 413190A HU 904131 D0 HU904131 D0 HU 904131D0
- Authority
- HU
- Hungary
- Prior art keywords
- compounds
- formula
- optionally substituted
- active substance
- heterocycle
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/20—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Lubricants (AREA)
- Eyeglasses (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Polyurethanes Or Polyureas (AREA)
- Pyrane Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP89402046 | 1989-07-18 | ||
| EP90401000 | 1990-04-11 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HU904131D0 true HU904131D0 (en) | 1990-12-28 |
| HU209889B HU209889B (en) | 1994-11-28 |
Family
ID=26123157
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU904131A HU209889B (en) | 1989-07-18 | 1990-07-09 | Process for the production of diaryl-ethers, thioethers and their derivatives and of pharmaceutical compositions containing the same |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US5208259A (hu) |
| EP (1) | EP0409413B1 (hu) |
| JP (1) | JPH0356474A (hu) |
| KR (1) | KR910002827A (hu) |
| AT (1) | ATE109477T1 (hu) |
| AU (1) | AU636357B2 (hu) |
| CA (1) | CA2019345A1 (hu) |
| DD (1) | DD300432A5 (hu) |
| DE (1) | DE69011234T2 (hu) |
| DK (1) | DK0409413T3 (hu) |
| ES (1) | ES2057410T3 (hu) |
| FI (1) | FI903622A0 (hu) |
| GB (1) | GB9015571D0 (hu) |
| HU (1) | HU209889B (hu) |
| IE (1) | IE64358B1 (hu) |
| IL (1) | IL94732A0 (hu) |
| NO (1) | NO903185L (hu) |
| NZ (1) | NZ234061A (hu) |
| PT (1) | PT94723A (hu) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8926981D0 (en) * | 1988-12-23 | 1990-01-17 | Ici Plc | Heterocyclic derivatives |
| GB9018134D0 (en) * | 1989-09-29 | 1990-10-03 | Ici Plc | Heterocyclic derivatives |
| US5254581A (en) * | 1990-06-21 | 1993-10-19 | Imperial Chemical Industries Plc | Pyran derivatives and their use as inhibitors of 5-lipoxygenase |
| IE911853A1 (en) * | 1990-06-21 | 1992-01-01 | Ici Plc | Heterocyclene derivatives |
| IE913866A1 (en) * | 1990-11-28 | 1992-06-03 | Ici Plc | Aryl derivatives |
| IE914005A1 (en) * | 1990-12-14 | 1992-06-17 | Zeneca Ltd | Novel intermediates |
| IL100483A0 (en) * | 1991-01-17 | 1992-09-06 | Ici Plc | Sulphonamide derivatives |
| US5281720A (en) * | 1991-02-28 | 1994-01-25 | Merck Frosst Canada, Inc. | Pyranylphenyl hydroxyalkylnaphthoic acids as inhibitors of leukotriene biosynthesis |
| EP0501578A1 (en) * | 1991-02-28 | 1992-09-02 | Merck Frosst Canada Inc. | Pyranylphenyl hydroxyalkylnaphthoic acids as inhibitors of leukotriene biosynthesis |
| EP0501579A1 (en) * | 1991-02-28 | 1992-09-02 | Merck Frosst Canada Inc. | Naphthalene lactones as inhibitors of leukotriene biosynthesis |
| US5227399A (en) * | 1991-02-28 | 1993-07-13 | Merck Frosst Canada, Inc. | Pyranylphenyl naphthalene lactones as inhibitors of leukotriene biosynthesis |
| GB9214120D0 (en) * | 1991-07-25 | 1992-08-12 | Ici Plc | Therapeutic amides |
| DE69206725T2 (de) * | 1991-09-10 | 1996-05-02 | Zeneca Ltd | Benzolsulfonamidderivate als 5-Lipoxygenasehemmer |
| GB9300894D0 (en) * | 1992-02-07 | 1993-03-10 | Zeneca Ltd | Oxime derivatives |
| EP0555067A1 (en) * | 1992-02-07 | 1993-08-11 | Zeneca Limited | Hydroxylamine derivatives as 5-lipoxygenase inhibitors |
| CA2094465A1 (en) * | 1992-04-23 | 1993-10-24 | Pierre Andre Raymond Bruneau | Cycloalkane derivatives |
| CA2095005A1 (en) * | 1992-05-12 | 1993-11-13 | Philip Neil Edwards | Hydroxylamine derivatives |
| CA2095006A1 (en) * | 1992-05-12 | 1993-11-13 | Philip Neil Edwards | Oxime derivatives |
| EP0570197B1 (en) * | 1992-05-12 | 1995-12-13 | Zeneca Limited | Hydroxylamine derivatives |
| IL105558A (en) * | 1992-05-18 | 1998-04-05 | Zeneca Ltd | Tertiary carbinols with channel activity potassium process for their preparation and pharmaceutical preparations containing them |
| JPH063890A (ja) * | 1992-06-24 | 1994-01-14 | Toshiba Corp | 画像形成装置 |
| US5308852A (en) * | 1992-06-29 | 1994-05-03 | Merck Frosst Canada, Inc. | Heteroarylnaphthalenes as inhibitors of leukotriene biosynthesis |
| EP0581464A1 (en) * | 1992-07-15 | 1994-02-02 | Zeneca Limited | Ester derivatives and pharmaceutical compositions containing them |
| US5350744A (en) * | 1992-08-27 | 1994-09-27 | Merck Frosst Canada, Inc. | Phenylnaphthalene lactones as inhibitors of leukotriene biosynthesis |
| US5252599A (en) * | 1992-08-27 | 1993-10-12 | Merck Frosst Canada, Inc. | Heteroarylnaphthalene hydroxy acids as inhibitors of leukotriene biosynthesis |
| US5426109A (en) * | 1992-08-27 | 1995-06-20 | Merck Frosst Canada, Inc. | Phenylnaphthalene hydroxy acids |
| US5428060A (en) * | 1992-08-27 | 1995-06-27 | Merck Frosst Canada, Inc. | Heteroarylnaphthalene lactones as inhibitors of leukotriene biosynthesis |
| EP0586229A1 (en) * | 1992-09-01 | 1994-03-09 | Zeneca Limited | 3-Hydroxy-3-(subst-akyl)-pyrrolidines as 5-lipoxygenase inhibitors |
| AU4444393A (en) * | 1992-09-01 | 1994-03-10 | Zeneca Limited | Pyrrolidine derivatives |
| GR920100426A (el) * | 1992-10-08 | 1994-06-30 | Ici Pharma | Παράγωγα βενζολοσουλφοναμιδίου. |
| IL108187A0 (en) * | 1993-01-28 | 1994-04-12 | Zenecca Limited | Oxime derivatives |
| GB9305295D0 (en) * | 1993-03-15 | 1993-05-05 | Zeneca Ltd | Therapeutic compounds |
| AP9400632A0 (en) * | 1993-04-29 | 1995-10-07 | Zeneca Ltd | Ether derivatives. |
| US5346914A (en) * | 1993-05-14 | 1994-09-13 | Abbott Laboratories | (4-alkoxypyran-4-yl) substituted arylalkylaryl-, arylalkenylaryl-, and arylalkynylarylurea inhibitors of 5-lipoxygenase |
| GB9310095D0 (en) * | 1993-05-17 | 1993-06-30 | Zeneca Ltd | Therapeutic compounds |
| EP0702678A1 (en) * | 1993-06-07 | 1996-03-27 | Zeneca Limited | Aniline derivatives |
| KR100190728B1 (ko) * | 1993-06-14 | 1999-06-01 | 디. 제이. 우드, 스피겔 알렌 제이 | 이미다졸 리폭시게나제 저해제 |
| IL115420A0 (en) | 1994-09-26 | 1995-12-31 | Zeneca Ltd | Aminoheterocyclic derivatives |
| GB9602166D0 (en) | 1996-02-02 | 1996-04-03 | Zeneca Ltd | Aminoheterocyclic derivatives |
| WO1997028128A1 (en) | 1996-02-02 | 1997-08-07 | Zeneca Limited | Heterocyclic compounds useful as pharmaceutical agents |
| WO1998006705A1 (en) * | 1996-08-14 | 1998-02-19 | Zeneca Limited | Substituted pyrimidine derivatives and their pharmaceutical use |
| UA56197C2 (uk) | 1996-11-08 | 2003-05-15 | Зенека Лімітед | Гетероциклічні похідні |
| WO1998035959A1 (en) | 1997-02-13 | 1998-08-20 | Zeneca Limited | Heterocyclic compounds useful as oxido-squalene cyclase inhibitors |
| WO1998035956A1 (en) | 1997-02-13 | 1998-08-20 | Zeneca Limited | Heterocyclic compounds useful as oxido-squalene cyclase inhibitors |
| GB9715895D0 (en) | 1997-07-29 | 1997-10-01 | Zeneca Ltd | Heterocyclic compounds |
| GB9902989D0 (en) | 1999-02-11 | 1999-03-31 | Zeneca Ltd | Heterocyclic derivatives |
| US7846915B2 (en) | 2004-10-20 | 2010-12-07 | Resverlogix Corporation | Stilbenes and chalcones for the prevention and treatment of cardiovascular diseases |
| AU2006275514B2 (en) | 2005-07-29 | 2012-04-05 | Resverlogix Corp. | Pharmaceutical compositions for the prevention and treatment of complex diseases and their delivery by insertable medical devices |
| CN101641339B (zh) | 2007-02-01 | 2013-07-17 | 雷斯韦洛吉克斯公司 | 用于预防和治疗心血管疾病的化合物 |
| KR101629356B1 (ko) | 2008-06-26 | 2016-06-13 | 리스버로직스 코퍼레이션 | 퀴나졸리논 유도체의 제조방법 |
| AU2010204106B2 (en) | 2009-01-08 | 2014-05-08 | Resverlogix Corp. | Compounds for the prevention and treatment of cardiovascular disease |
| MX2021012876A (es) | 2009-03-18 | 2022-06-23 | Resverlogix Corp | Nuevos agentes anti-inflamatorios. |
| ES2821018T3 (es) | 2009-04-22 | 2021-04-23 | Resverlogix Corp | Nuevos agentes antiinflamatorios |
| PT2773354T (pt) | 2011-11-01 | 2019-07-17 | Resverlogix Corp | Formulações orais de libertação imediata para quinazolinonas substituídas |
| WO2014080291A2 (en) | 2012-11-21 | 2014-05-30 | Rvx Therapeutics Inc. | Biaryl derivatives as bromodomain inhibitors |
| US9073878B2 (en) | 2012-11-21 | 2015-07-07 | Zenith Epigenetics Corp. | Cyclic amines as bromodomain inhibitors |
| AU2013365926B9 (en) | 2012-12-21 | 2019-01-17 | Zenith Epigenetics Ltd. | Novel heterocyclic compounds as bromodomain inhibitors |
| US10111885B2 (en) | 2015-03-13 | 2018-10-30 | Resverlogix Corp. | Compositions and therapeutic methods for the treatment of complement-associated diseases |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4207241A (en) * | 1967-01-13 | 1980-06-10 | Syntex Corporation | 2-Naphthyl acetic acid derivatives and compositions and methods thereof |
| US3743737A (en) * | 1970-05-21 | 1973-07-03 | Smith Kline French Lab | 3-sulfonamido-4-hydroxyphenyl-2-piperindinylcarbinol compositions |
| US3661917A (en) * | 1970-05-21 | 1972-05-09 | Smith Kline French Lab | 3-sulfonamido-4-hydroxyphenyl-2-piperidylcarbinols |
| IE56702B1 (en) * | 1982-12-01 | 1991-11-06 | Usv Pharma Corp | Antiinflammatory antiallergic compounds |
| NO174506B (no) * | 1984-10-30 | 1994-02-07 | Usv Pharma Corp | Analogifremgangsmaate ved fremstilling av terapeutisk aktive forbindelser |
| US4625034A (en) * | 1985-02-04 | 1986-11-25 | Usv Pharmaceutical Corp. | 1,2-Dihydro; 1,2,3,4-tetrahydro; 5,8 dihydro; and 5,6,7,8-tetrahydroquinoline derivatives |
| US4839369A (en) * | 1985-04-16 | 1989-06-13 | Rorer Pharmaceutical Corporation | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments |
| DE3622599A1 (de) * | 1986-07-05 | 1988-01-14 | Basf Ag | Pyranderivate, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung von schaedlingen |
| EP0271287A3 (en) * | 1986-12-11 | 1990-06-13 | Merck Frosst Canada Inc. | Quinoline dioic acids and amides |
| US4920130A (en) * | 1987-11-02 | 1990-04-24 | Rorer Pharamceutical Corp. | Quinoline derivatives and use thereof as antagonists of leukotriene D4 |
| US4920133A (en) * | 1987-11-03 | 1990-04-24 | Rorer Pharmaceutical Corp. | Quinoline derivatives and use thereof as antagonists of leukotriene D4 |
| US4920132A (en) * | 1987-11-03 | 1990-04-24 | Rorer Pharmaceutical Corp. | Quinoline derivatives and use thereof as antagonists of leukotriene D4 |
| US4920131A (en) * | 1987-11-03 | 1990-04-24 | Rorer Pharmaceutical Corp. | Quinoline derivatives and use thereof as antagonists of leukotriene D4 |
| US4918081A (en) * | 1988-06-20 | 1990-04-17 | Rorer Pharmaceutical Corp. | Quinoline derivatives and use thereof as antagonists of leukotriene d4 |
| EP0349062A1 (en) * | 1988-06-27 | 1990-01-03 | Merck Frosst Canada Inc. | Quinoline ether alkanoic acid |
| GB8926981D0 (en) * | 1988-12-23 | 1990-01-17 | Ici Plc | Heterocyclic derivatives |
-
1990
- 1990-06-12 IE IE211290A patent/IE64358B1/en not_active IP Right Cessation
- 1990-06-13 NZ NZ234061A patent/NZ234061A/xx unknown
- 1990-06-14 IL IL94732A patent/IL94732A0/xx unknown
- 1990-06-19 AU AU57575/90A patent/AU636357B2/en not_active Ceased
- 1990-06-20 CA CA002019345A patent/CA2019345A1/en not_active Abandoned
- 1990-06-20 EP EP90306765A patent/EP0409413B1/en not_active Expired - Lifetime
- 1990-06-20 DE DE69011234T patent/DE69011234T2/de not_active Expired - Fee Related
- 1990-06-20 DK DK90306765.0T patent/DK0409413T3/da active
- 1990-06-20 ES ES90306765T patent/ES2057410T3/es not_active Expired - Lifetime
- 1990-06-20 AT AT90306765T patent/ATE109477T1/de active
- 1990-06-30 KR KR1019900009970A patent/KR910002827A/ko not_active Application Discontinuation
- 1990-07-03 US US07/547,229 patent/US5208259A/en not_active Expired - Fee Related
- 1990-07-09 HU HU904131A patent/HU209889B/hu not_active IP Right Cessation
- 1990-07-16 GB GB909015571A patent/GB9015571D0/en active Pending
- 1990-07-17 PT PT94723A patent/PT94723A/pt not_active Application Discontinuation
- 1990-07-17 NO NO90903185A patent/NO903185L/no unknown
- 1990-07-18 FI FI903622A patent/FI903622A0/fi not_active Application Discontinuation
- 1990-07-18 JP JP2188155A patent/JPH0356474A/ja active Pending
- 1990-07-18 DD DD342895A patent/DD300432A5/de unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2019345A1 (en) | 1991-01-18 |
| ES2057410T3 (es) | 1994-10-16 |
| AU5757590A (en) | 1991-01-24 |
| NO903185L (no) | 1991-01-21 |
| JPH0356474A (ja) | 1991-03-12 |
| EP0409413B1 (en) | 1994-08-03 |
| NO903185D0 (no) | 1990-07-17 |
| EP0409413A2 (en) | 1991-01-23 |
| GB9015571D0 (en) | 1990-09-05 |
| NZ234061A (en) | 1993-02-25 |
| AU636357B2 (en) | 1993-04-29 |
| IL94732A0 (en) | 1991-04-15 |
| EP0409413A3 (en) | 1991-07-17 |
| DD300432A5 (de) | 1992-06-11 |
| US5208259A (en) | 1993-05-04 |
| ATE109477T1 (de) | 1994-08-15 |
| FI903622A0 (fi) | 1990-07-18 |
| PT94723A (pt) | 1991-03-20 |
| KR910002827A (ko) | 1991-02-26 |
| DE69011234D1 (de) | 1994-09-08 |
| DE69011234T2 (de) | 1994-12-08 |
| IE64358B1 (en) | 1995-07-26 |
| IE902112A1 (en) | 1991-06-19 |
| HU209889B (en) | 1994-11-28 |
| DK0409413T3 (da) | 1994-08-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| HMM4 | Cancellation of final prot. due to non-payment of fee |