HU201547B - Process for producing 2-oxo-1-brackets open brackets open (substituted sulfonyl)-amino brackets closed-carbonyl brackets closed-acetidines and pharmaceutical compositions comprising same - Google Patents
Process for producing 2-oxo-1-brackets open brackets open (substituted sulfonyl)-amino brackets closed-carbonyl brackets closed-acetidines and pharmaceutical compositions comprising sameInfo
- Publication number
- HU201547B HU201547B HU884349A HU434988A HU201547B HU 201547 B HU201547 B HU 201547B HU 884349 A HU884349 A HU 884349A HU 434988 A HU434988 A HU 434988A HU 201547 B HU201547 B HU 201547B
- Authority
- HU
- Hungary
- Prior art keywords
- brackets
- closed
- open
- acetidines
- oxo
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/085,050 US4777252A (en) | 1987-08-13 | 1987-08-13 | 2-oxo-1-[[(substituted sulfonyl)amino]-carbonyl]azetidines |
Publications (2)
Publication Number | Publication Date |
---|---|
HUT48235A HUT48235A (en) | 1989-05-29 |
HU201547B true HU201547B (en) | 1990-11-28 |
Family
ID=22189148
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU884349A HU201547B (en) | 1987-08-13 | 1988-08-12 | Process for producing 2-oxo-1-brackets open brackets open (substituted sulfonyl)-amino brackets closed-carbonyl brackets closed-acetidines and pharmaceutical compositions comprising same |
Country Status (8)
Country | Link |
---|---|
US (1) | US4777252A (hu) |
EP (1) | EP0303286A1 (hu) |
JP (1) | JPH0196181A (hu) |
AU (1) | AU2091988A (hu) |
DK (1) | DK454188A (hu) |
HU (1) | HU201547B (hu) |
NZ (1) | NZ225821A (hu) |
ZA (1) | ZA885998B (hu) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0357604A1 (en) * | 1987-02-27 | 1990-03-14 | The Upjohn Company | Antibiotic beta-lactams containing a pyridone carboxylic acid or acid derivative |
US4904775A (en) * | 1988-05-16 | 1990-02-27 | E. R. Squibb & Sons, Inc. | Heteroaroylhydrazide derivatives of monocyclic beta-lactam antibiotics |
FR2653429B1 (fr) * | 1989-10-25 | 1991-12-20 | Adir | Nouveaux derives de l'azetidin-2-one, 1,3,4-trisubstitues, intermediaires utiles pour la synthese des beta-lactames, et leur procede de synthese asymetrique. |
GB9008850D0 (en) * | 1990-04-19 | 1990-06-13 | Janssen Pharmaceutica Nv | Novel 2,9-disubstituted-4h-pyridol(1,2-a)pyrimidin-4-ones |
IL99658A0 (en) * | 1990-10-15 | 1992-08-18 | Merck & Co Inc | Substituted azetidinones and pharmaceutical compositions containing them |
RU2220960C2 (ru) * | 1997-12-22 | 2004-01-10 | Фармация Энд Апджон Компани | 4-гидрокси-3-хинолинкарбоксамиды и гидразиды, фармацевтическая композиция и способ лечения на их основе |
DE60018274T2 (de) * | 1999-05-06 | 2005-08-04 | Neurogen Corp., Branford | Substituierte 4-oxo-chinolin-3-carboxamide als gaba gehirnrezeptorliganden |
US20100074949A1 (en) | 2008-08-13 | 2010-03-25 | William Rowe | Pharmaceutical composition and administration thereof |
US7056917B2 (en) * | 2001-04-26 | 2006-06-06 | Daiichi Pharmaceutical Co., Ltd. | Drug efflux pump inhibitor |
EP1389463A4 (en) * | 2001-04-26 | 2008-09-17 | Daiichi Seiyaku Co | MEDICAMENT FOR INHIBITING A DRUG REMOVAL PUMP |
NZ587551A (en) * | 2004-06-24 | 2012-01-12 | Vertex Pharma | 5-Amino-phenol derivatives such as 5-amino-2,4-di-tert-butyl-phenol |
US8354427B2 (en) | 2004-06-24 | 2013-01-15 | Vertex Pharmaceutical Incorporated | Modulators of ATP-binding cassette transporters |
JP2006131568A (ja) * | 2004-11-08 | 2006-05-25 | Ueno Seiyaku Oyo Kenkyusho:Kk | ヒドロキシナフトエ酸ヒドラジドおよびその誘導体ならびにその製造方法 |
US20090105272A1 (en) * | 2005-12-24 | 2009-04-23 | Grootenhuis Peter D J | Prodrugs of modulators of ABC transporters |
PL3219705T3 (pl) * | 2005-12-28 | 2020-08-10 | Vertex Pharmaceuticals Incorporated | Kompozycje farmaceutyczne amorficznych postaci n-[2,4-bis(1,1-dimetyloetylo)-5-hydroksyfenylo]-1,4-dihydro-4-oksochinolino-3-karboksyamidu |
WO2010070523A1 (en) | 2008-12-19 | 2010-06-24 | Pfizer Inc. | Monocarbams |
KR101852173B1 (ko) | 2009-03-20 | 2018-04-27 | 버텍스 파마슈티칼스 인코포레이티드 | 낭성 섬유증 막횡단 전도도 조절자의 조정자의 제조 방법 |
DK2493871T3 (da) | 2009-10-30 | 2014-11-10 | Prestwick Chemical Sas | Nye oximderivater samt deres anvendelse som allosteriske modulatorer af metabotropiske glutamatreceptorer |
US8802700B2 (en) | 2010-12-10 | 2014-08-12 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-Binding Cassette transporters |
CN109966264A (zh) | 2012-02-27 | 2019-07-05 | 沃泰克斯药物股份有限公司 | 药物组合物及其施用 |
RS58592B1 (sr) | 2014-08-27 | 2019-05-31 | Prexton Therapeutics Sa | Novi derivat hromon oksima i njegova upotreba kao alosterni modulator metabotropnih glutamatnih receptora |
US9701639B2 (en) | 2014-10-07 | 2017-07-11 | Vertex Pharmaceuticals Incorporated | Co-crystals of modulators of cystic fibrosis transmembrane conductance regulator |
MX2018002255A (es) | 2015-08-27 | 2018-06-06 | Prexton Therapeutics Sa | Derivado de oxima de cromona penetrante del cerebro para la terapia de disquinesia inducida por levodopa. |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4587047A (en) * | 1981-04-09 | 1986-05-06 | E. R. Squibb & Sons, Inc. | 2-oxo-1-[[(substituted sulfonyl)amino]-carbonyl]azetidines |
NZ199981A (en) * | 1981-04-09 | 1985-08-16 | Squibb & Sons Inc | 2-oxo-1-(((substituted sulphonyl)amino)carbonyl)azetidines |
EG18314A (en) * | 1985-09-26 | 1993-02-28 | Squibb & Sons Inc | Process for preparing of 2-oxo-1((substituted sulfonyl)amino)carbonyl)-azitidines |
EP0246786A1 (en) * | 1986-05-23 | 1987-11-25 | The Upjohn Company | N-1 subsituted sulfonylaminocarbonyl, C-4 substituted monobactams |
US4801705A (en) * | 1986-06-23 | 1989-01-31 | E. R. Squibb & Sons, Inc. | 2-oxo-1-(((substituted sulfonyl)amino)-carbonyl)azetidines |
-
1987
- 1987-08-13 US US07/085,050 patent/US4777252A/en not_active Expired - Fee Related
-
1988
- 1988-08-12 AU AU20919/88A patent/AU2091988A/en not_active Abandoned
- 1988-08-12 HU HU884349A patent/HU201547B/hu not_active IP Right Cessation
- 1988-08-12 EP EP88113156A patent/EP0303286A1/en not_active Ceased
- 1988-08-12 JP JP63202599A patent/JPH0196181A/ja active Pending
- 1988-08-12 ZA ZA885998A patent/ZA885998B/xx unknown
- 1988-08-12 NZ NZ225821A patent/NZ225821A/en unknown
- 1988-08-12 DK DK454188A patent/DK454188A/da not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
HUT48235A (en) | 1989-05-29 |
NZ225821A (en) | 1990-11-27 |
DK454188D0 (da) | 1988-08-12 |
US4777252A (en) | 1988-10-11 |
AU2091988A (en) | 1989-02-16 |
EP0303286A1 (en) | 1989-02-15 |
DK454188A (da) | 1989-02-14 |
ZA885998B (en) | 1989-04-26 |
JPH0196181A (ja) | 1989-04-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
HMM4 | Cancellation of final prot. due to non-payment of fee |