ZA885998B - 2-oxo-1-((substituted sulfonyl)amino)carbonyl)-azetidines - Google Patents
2-oxo-1-((substituted sulfonyl)amino)carbonyl)-azetidinesInfo
- Publication number
- ZA885998B ZA885998B ZA885998A ZA885998A ZA885998B ZA 885998 B ZA885998 B ZA 885998B ZA 885998 A ZA885998 A ZA 885998A ZA 885998 A ZA885998 A ZA 885998A ZA 885998 B ZA885998 B ZA 885998B
- Authority
- ZA
- South Africa
- Prior art keywords
- azetidines
- oxo
- carbonyl
- amino
- substituted sulfonyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/085,050 US4777252A (en) | 1987-08-13 | 1987-08-13 | 2-oxo-1-[[(substituted sulfonyl)amino]-carbonyl]azetidines |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA885998B true ZA885998B (en) | 1989-04-26 |
Family
ID=22189148
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA885998A ZA885998B (en) | 1987-08-13 | 1988-08-12 | 2-oxo-1-((substituted sulfonyl)amino)carbonyl)-azetidines |
Country Status (8)
Country | Link |
---|---|
US (1) | US4777252A (xx) |
EP (1) | EP0303286A1 (xx) |
JP (1) | JPH0196181A (xx) |
AU (1) | AU2091988A (xx) |
DK (1) | DK454188A (xx) |
HU (1) | HU201547B (xx) |
NZ (1) | NZ225821A (xx) |
ZA (1) | ZA885998B (xx) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH02502455A (ja) * | 1987-02-27 | 1990-08-09 | ジ・アップジョン・カンパニー | ピリドンカルボン酸または酸誘導体を含有する抗生物質β‐ラクタム |
US4904775A (en) * | 1988-05-16 | 1990-02-27 | E. R. Squibb & Sons, Inc. | Heteroaroylhydrazide derivatives of monocyclic beta-lactam antibiotics |
FR2653429B1 (fr) * | 1989-10-25 | 1991-12-20 | Adir | Nouveaux derives de l'azetidin-2-one, 1,3,4-trisubstitues, intermediaires utiles pour la synthese des beta-lactames, et leur procede de synthese asymetrique. |
GB9008850D0 (en) * | 1990-04-19 | 1990-06-13 | Janssen Pharmaceutica Nv | Novel 2,9-disubstituted-4h-pyridol(1,2-a)pyrimidin-4-ones |
IL99658A0 (en) * | 1990-10-15 | 1992-08-18 | Merck & Co Inc | Substituted azetidinones and pharmaceutical compositions containing them |
CA2309882A1 (en) * | 1997-12-22 | 1999-07-01 | Pharmacia & Upjohn Company | 4-hydroxyquinoline-3-carboxamides and hydrazides as antiviral agents |
AU4818000A (en) * | 1999-05-06 | 2000-11-21 | Neurogen Corporation | Substituted 4-oxo-quinoline-3-carboxamides: gaba brain receptor ligands |
US20100074949A1 (en) | 2008-08-13 | 2010-03-25 | William Rowe | Pharmaceutical composition and administration thereof |
US7056917B2 (en) * | 2001-04-26 | 2006-06-06 | Daiichi Pharmaceutical Co., Ltd. | Drug efflux pump inhibitor |
CA2445697A1 (en) * | 2001-04-26 | 2002-11-07 | Daiichi Pharmaceutical Co., Ltd. | Drug efflux pump inhibitor |
LT2502911T (lt) | 2004-06-24 | 2017-09-11 | Vertex Pharmaceuticals Incorporated | Atp surišančios kasetės transporterių moduliatoriai |
US8354427B2 (en) * | 2004-06-24 | 2013-01-15 | Vertex Pharmaceutical Incorporated | Modulators of ATP-binding cassette transporters |
JP2006131568A (ja) * | 2004-11-08 | 2006-05-25 | Ueno Seiyaku Oyo Kenkyusho:Kk | ヒドロキシナフトエ酸ヒドラジドおよびその誘導体ならびにその製造方法 |
US20090105272A1 (en) * | 2005-12-24 | 2009-04-23 | Grootenhuis Peter D J | Prodrugs of modulators of ABC transporters |
PT3219705T (pt) | 2005-12-28 | 2020-05-20 | Vertex Pharma | Composições farmacêuticas da forma amorfa de n-[2,4-bis(1,1-dimetiletil)-5-hidroxifenil]-1,4-di-hidro-4-oxoquinolina-3-carboxamida |
CA2744756C (en) | 2008-12-19 | 2013-05-28 | Pfizer Inc. | Monocarbams and their use as antibacterial agent |
EP2821400B1 (en) | 2009-03-20 | 2017-09-27 | Vertex Pharmaceuticals Incorporated | Process for making modulators of cystic fibrosis transmembrane conductance regulator |
JP5806672B2 (ja) | 2009-10-30 | 2015-11-10 | ドメイン・セラピューティクス | 新規オキシム誘導体及び代謝型グルタミン酸受容体のアロステリック調節因子としての利用 |
US8802700B2 (en) | 2010-12-10 | 2014-08-12 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-Binding Cassette transporters |
IL265430B2 (en) | 2012-02-27 | 2024-08-01 | Vertex Pharma | Pharmaceutical preparations containing a solid dispersion of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide and uses thereof |
DK3186257T3 (en) | 2014-08-27 | 2019-04-01 | Prexton Therapeutics Sa | Hitherto UNKNOWN CHROMONOXIME DERIVATIVE AND ITS USE AS AN ALLOSTERIC MODULATOR OF METABOTROPIC GLUTAMATE RECEPTORS |
KR20170063954A (ko) | 2014-10-07 | 2017-06-08 | 버텍스 파마슈티칼스 인코포레이티드 | 낭성 섬유증 막횡단 전도도 조절자의 조정제의 공-결정 |
MA42700B1 (fr) | 2015-08-27 | 2019-12-31 | Prexton Therapeutics Sa | Dérivé d'oxime de chromone et son utilisation comme modulateur allostérique de récepteurs métabotropiques du glutamate |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ199981A (en) * | 1981-04-09 | 1985-08-16 | Squibb & Sons Inc | 2-oxo-1-(((substituted sulphonyl)amino)carbonyl)azetidines |
US4587047A (en) * | 1981-04-09 | 1986-05-06 | E. R. Squibb & Sons, Inc. | 2-oxo-1-[[(substituted sulfonyl)amino]-carbonyl]azetidines |
EG18314A (en) * | 1985-09-26 | 1993-02-28 | Squibb & Sons Inc | Process for preparing of 2-oxo-1((substituted sulfonyl)amino)carbonyl)-azitidines |
JPH01502660A (ja) * | 1986-05-23 | 1989-09-14 | ジ・アップジョン・カンパニー | N―1置換スルホニルアミノカルボニル、c―4置換モノバクタム類 |
US4801705A (en) * | 1986-06-23 | 1989-01-31 | E. R. Squibb & Sons, Inc. | 2-oxo-1-(((substituted sulfonyl)amino)-carbonyl)azetidines |
-
1987
- 1987-08-13 US US07/085,050 patent/US4777252A/en not_active Expired - Fee Related
-
1988
- 1988-08-12 JP JP63202599A patent/JPH0196181A/ja active Pending
- 1988-08-12 HU HU884349A patent/HU201547B/hu not_active IP Right Cessation
- 1988-08-12 NZ NZ225821A patent/NZ225821A/en unknown
- 1988-08-12 EP EP88113156A patent/EP0303286A1/en not_active Ceased
- 1988-08-12 AU AU20919/88A patent/AU2091988A/en not_active Abandoned
- 1988-08-12 DK DK454188A patent/DK454188A/da not_active Application Discontinuation
- 1988-08-12 ZA ZA885998A patent/ZA885998B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
HU201547B (en) | 1990-11-28 |
DK454188A (da) | 1989-02-14 |
HUT48235A (en) | 1989-05-29 |
AU2091988A (en) | 1989-02-16 |
EP0303286A1 (en) | 1989-02-15 |
JPH0196181A (ja) | 1989-04-14 |
NZ225821A (en) | 1990-11-27 |
US4777252A (en) | 1988-10-11 |
DK454188D0 (da) | 1988-08-12 |
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