HU186282B - Process for the preparation of bisindol compounds - Google Patents

Process for the preparation of bisindol compounds Download PDF

Info

Publication number
HU186282B
HU186282B HU801775A HU177580A HU186282B HU 186282 B HU186282 B HU 186282B HU 801775 A HU801775 A HU 801775A HU 177580 A HU177580 A HU 177580A HU 186282 B HU186282 B HU 186282B
Authority
HU
Hungary
Prior art keywords
formula
compound
methyl
solvent
compounds
Prior art date
Application number
HU801775A
Other languages
English (en)
Hungarian (hu)
Inventor
Pierre Potier
Nicole Langlois
Yves Langlois
Ratremaniaina Z Andriamialisoa
Pierre Mangeney
Original Assignee
Anvar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anvar filed Critical Anvar
Publication of HU186282B publication Critical patent/HU186282B/hu

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04Dimeric indole alkaloids, e.g. vincaleucoblastine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
HU801775A 1979-07-17 1980-07-16 Process for the preparation of bisindol compounds HU186282B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7918453A FR2461714A1 (fr) 1979-07-17 1979-07-17 Nouvelle classe de composes bis-indoliques utiles comme medicaments et procede pour leur preparation

Publications (1)

Publication Number Publication Date
HU186282B true HU186282B (en) 1985-07-29

Family

ID=9227964

Family Applications (1)

Application Number Title Priority Date Filing Date
HU801775A HU186282B (en) 1979-07-17 1980-07-16 Process for the preparation of bisindol compounds

Country Status (7)

Country Link
US (1) US4347249A (enExample)
EP (1) EP0022730B1 (enExample)
JP (1) JPS5622786A (enExample)
CA (1) CA1182456A (enExample)
DE (1) DE3062620D1 (enExample)
FR (1) FR2461714A1 (enExample)
HU (1) HU186282B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE59102889D1 (de) * 1990-03-26 1994-10-20 Lonza Ag Verfahren und Einrichtung zum intervallweisen Versprühen einer Schmiermittel-Suspension.
JP5448299B2 (ja) * 2003-12-04 2014-03-19 アルバニー モレキュラー リサーチ, インコーポレイテッド ビンカ誘導体
EP1694330A4 (en) * 2003-12-04 2009-06-24 Amr Technology Inc DERIVATIVES OF VINORELBINE
JP5596924B2 (ja) * 2006-02-17 2014-09-24 カスケード プロドラッグ インコーポレイテッド ビンカアルカロイドn酸化物および類似体による過剰増殖疾患の処置
US8039453B2 (en) * 2006-09-12 2011-10-18 Albany Molecular Research, Inc. Vinca derivatives
US20080125451A1 (en) * 2006-09-12 2008-05-29 Amr Technology, Inc. Vinorelbine derivatives

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3392173A (en) 1964-03-09 1968-07-09 Lilly Co Eli Novel acyl derivatives of desacetyl-vincaleukoblastine and processes for their preparation
US3352868A (en) 1964-04-01 1967-11-14 Lilly Co Eli Dihydrovinblastine
DE1545768A1 (de) * 1964-06-18 1969-11-27 Lilly Co Eli Indolyl-Vindoline und Verfahren zu ihrer Herstellung
US4279817A (en) * 1975-05-30 1981-07-21 The United States Of America As Represented By The Department Of Health & Human Services Method for producing dimer alkaloids
US4122081A (en) * 1977-08-08 1978-10-24 Eli Lilly And Company 5'-Hydroxyleurosine and related compounds
FR2434172A1 (fr) * 1978-08-24 1980-03-21 Anvar Nouveaux composes intermediaires utiles dans la synthese de derives bis-indoliques et procede pour leur preparation
US4307100A (en) * 1978-08-24 1981-12-22 Agence Nationale De Valorisation De La Recherche (Anvar) Nor bis-indole compounds usable as medicaments

Also Published As

Publication number Publication date
FR2461714A1 (fr) 1981-02-06
EP0022730A1 (fr) 1981-01-21
CA1182456A (fr) 1985-02-12
US4347249A (en) 1982-08-31
DE3062620D1 (en) 1983-05-11
JPS5622786A (en) 1981-03-03
FR2461714B1 (enExample) 1981-09-04
EP0022730B1 (fr) 1983-04-06

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