HU186282B - Process for the preparation of bisindol compounds - Google Patents
Process for the preparation of bisindol compounds Download PDFInfo
- Publication number
- HU186282B HU186282B HU801775A HU177580A HU186282B HU 186282 B HU186282 B HU 186282B HU 801775 A HU801775 A HU 801775A HU 177580 A HU177580 A HU 177580A HU 186282 B HU186282 B HU 186282B
- Authority
- HU
- Hungary
- Prior art keywords
- formula
- compound
- methyl
- solvent
- compounds
- Prior art date
Links
- 0 CCC1([C@]2*)C=CCN(CC3)C1C31c(cc([C@](CCCC(*)*C(*)(CN*)*=C)(C(OC)=O)C(*3)=C(*)c4c3cccc4)c(OC)c3)c3N(C)[C@@]1CC[C@@]2(C)IC(OC)=O Chemical compound CCC1([C@]2*)C=CCN(CC3)C1C31c(cc([C@](CCCC(*)*C(*)(CN*)*=C)(C(OC)=O)C(*3)=C(*)c4c3cccc4)c(OC)c3)c3N(C)[C@@]1CC[C@@]2(C)IC(OC)=O 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7918453A FR2461714A1 (fr) | 1979-07-17 | 1979-07-17 | Nouvelle classe de composes bis-indoliques utiles comme medicaments et procede pour leur preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HU186282B true HU186282B (en) | 1985-07-29 |
Family
ID=9227964
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU801775A HU186282B (en) | 1979-07-17 | 1980-07-16 | Process for the preparation of bisindol compounds |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US4347249A (enExample) |
| EP (1) | EP0022730B1 (enExample) |
| JP (1) | JPS5622786A (enExample) |
| CA (1) | CA1182456A (enExample) |
| DE (1) | DE3062620D1 (enExample) |
| FR (1) | FR2461714A1 (enExample) |
| HU (1) | HU186282B (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE59102889D1 (de) * | 1990-03-26 | 1994-10-20 | Lonza Ag | Verfahren und Einrichtung zum intervallweisen Versprühen einer Schmiermittel-Suspension. |
| JP5448299B2 (ja) * | 2003-12-04 | 2014-03-19 | アルバニー モレキュラー リサーチ, インコーポレイテッド | ビンカ誘導体 |
| EP1694330A4 (en) * | 2003-12-04 | 2009-06-24 | Amr Technology Inc | DERIVATIVES OF VINORELBINE |
| JP5596924B2 (ja) * | 2006-02-17 | 2014-09-24 | カスケード プロドラッグ インコーポレイテッド | ビンカアルカロイドn酸化物および類似体による過剰増殖疾患の処置 |
| US8039453B2 (en) * | 2006-09-12 | 2011-10-18 | Albany Molecular Research, Inc. | Vinca derivatives |
| US20080125451A1 (en) * | 2006-09-12 | 2008-05-29 | Amr Technology, Inc. | Vinorelbine derivatives |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3392173A (en) | 1964-03-09 | 1968-07-09 | Lilly Co Eli | Novel acyl derivatives of desacetyl-vincaleukoblastine and processes for their preparation |
| US3352868A (en) | 1964-04-01 | 1967-11-14 | Lilly Co Eli | Dihydrovinblastine |
| DE1545768A1 (de) * | 1964-06-18 | 1969-11-27 | Lilly Co Eli | Indolyl-Vindoline und Verfahren zu ihrer Herstellung |
| US4279817A (en) * | 1975-05-30 | 1981-07-21 | The United States Of America As Represented By The Department Of Health & Human Services | Method for producing dimer alkaloids |
| US4122081A (en) * | 1977-08-08 | 1978-10-24 | Eli Lilly And Company | 5'-Hydroxyleurosine and related compounds |
| FR2434172A1 (fr) * | 1978-08-24 | 1980-03-21 | Anvar | Nouveaux composes intermediaires utiles dans la synthese de derives bis-indoliques et procede pour leur preparation |
| US4307100A (en) * | 1978-08-24 | 1981-12-22 | Agence Nationale De Valorisation De La Recherche (Anvar) | Nor bis-indole compounds usable as medicaments |
-
1979
- 1979-07-17 FR FR7918453A patent/FR2461714A1/fr active Granted
-
1980
- 1980-07-09 US US06/167,377 patent/US4347249A/en not_active Expired - Lifetime
- 1980-07-14 CA CA000356147A patent/CA1182456A/fr not_active Expired
- 1980-07-16 DE DE8080401067T patent/DE3062620D1/de not_active Expired
- 1980-07-16 EP EP80401067A patent/EP0022730B1/fr not_active Expired
- 1980-07-16 HU HU801775A patent/HU186282B/hu unknown
- 1980-07-17 JP JP9814880A patent/JPS5622786A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| FR2461714A1 (fr) | 1981-02-06 |
| EP0022730A1 (fr) | 1981-01-21 |
| CA1182456A (fr) | 1985-02-12 |
| US4347249A (en) | 1982-08-31 |
| DE3062620D1 (en) | 1983-05-11 |
| JPS5622786A (en) | 1981-03-03 |
| FR2461714B1 (enExample) | 1981-09-04 |
| EP0022730B1 (fr) | 1983-04-06 |
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