HU177732B - Process for producing 10-bromo-vincamine and acid additional salts thereof,and 10-bromo-14-epivincamine - Google Patents

Process for producing 10-bromo-vincamine and acid additional salts thereof,and 10-bromo-14-epivincamine

Info

Publication number
HU177732B
HU177732B HURI000692A HU177732B HU 177732 B HU177732 B HU 177732B HU RI000692 A HURI000692 A HU RI000692A HU 177732 B HU177732 B HU 177732B
Authority
HU
Hungary
Prior art keywords
bromo
epivincamine
vincamine
producing
additional salts
Prior art date
Application number
Other languages
English (en)
Hungarian (hu)
Inventor
Csaba Szantay
Lajos Szabo
Gyoergy Klaus
Lajos Dancsi
Tibor Keve
Zsuzsanna Gyulai
Egon Karpati
Laszlo Szporny
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Priority to HURI000692 priority Critical patent/HU177732B/hu
Priority to ES486799A priority patent/ES486799A1/es
Priority to FR7930800A priority patent/FR2444037B1/fr
Priority to GB7943199A priority patent/GB2039900A/en
Priority to CH1108379A priority patent/CH658059A5/de
Priority to DE19792950436 priority patent/DE2950436A1/de
Priority to JP16220779A priority patent/JPS5583784A/ja
Publication of HU177732B publication Critical patent/HU177732B/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HURI000692 1978-12-15 1978-12-15 Process for producing 10-bromo-vincamine and acid additional salts thereof,and 10-bromo-14-epivincamine HU177732B (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
HURI000692 HU177732B (en) 1978-12-15 1978-12-15 Process for producing 10-bromo-vincamine and acid additional salts thereof,and 10-bromo-14-epivincamine
ES486799A ES486799A1 (es) 1978-12-15 1979-12-12 Un procedimiento de preparacion de 10-bromo-vincamina
FR7930800A FR2444037B1 (fr) 1978-12-15 1979-12-14 Procede de preparation de 10-bromovincamines et composes obtenus
GB7943199A GB2039900A (en) 1978-12-15 1979-12-14 Octahydro-indolo[2,3- a]quinolisine derivative
CH1108379A CH658059A5 (de) 1978-12-15 1979-12-14 Verfahren zur herstellung von 10-brom-vincaminen.
DE19792950436 DE2950436A1 (de) 1978-12-15 1979-12-14 1 alpha -aethyl-1 beta - eckige klammer auf 2'-(methoxycarbonyl)-aethyl eckige klammer zu -9-brom-1,2,3,4,6,7,12,12b -octahydroindolo eckige klammer auf 2,3-a eckige klammer zu chinolizinderivate, verfahren zur herstellung derselben bzw. von 10-bromvincamin und 10-brom-14-epivincamin, erstere enthaltende arzneimittel sowie 1-aethyl-1- eckige klammer auf 2'- (acetoxy)-2'-(methoxycarbonyl)-aethyl eckige klammer zu -9-brom-1,2,3,4,6,7- hexahydro-12h-indolo eckige klammer auf 2,3-a eckige klammer zu chinolizin-5- iumperchlorat und 1-aethyl-1- eckige klammer auf 2'-(hydroxy)-2'-(methoxycarbonyl)- aethyl eckige klammer zu -9-brom-1,2,3,4, 6,7-hexahydro-12h-indolo eckige klammer auf 2,3-a eckige klammer zu chinolizin- 5-iumperchlorat
JP16220779A JPS5583784A (en) 1978-12-15 1979-12-15 Manufacture of 100bromovincamines

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HURI000692 HU177732B (en) 1978-12-15 1978-12-15 Process for producing 10-bromo-vincamine and acid additional salts thereof,and 10-bromo-14-epivincamine

Publications (1)

Publication Number Publication Date
HU177732B true HU177732B (en) 1981-12-28

Family

ID=11001079

Family Applications (1)

Application Number Title Priority Date Filing Date
HURI000692 HU177732B (en) 1978-12-15 1978-12-15 Process for producing 10-bromo-vincamine and acid additional salts thereof,and 10-bromo-14-epivincamine

Country Status (7)

Country Link
JP (1) JPS5583784A (de)
CH (1) CH658059A5 (de)
DE (1) DE2950436A1 (de)
ES (1) ES486799A1 (de)
FR (1) FR2444037B1 (de)
GB (1) GB2039900A (de)
HU (1) HU177732B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4315011A (en) * 1978-07-12 1982-02-09 Richter Gedeon Vegyeszeti Gyar Rt. 1-Alkyl-9-bromohexahydroindolo quinolizium salts and use thereof to increase blood flow
HU181496B (en) * 1979-08-13 1983-07-28 Richter Gedeon Vegyeszet Process for preparing 10-bromo-15-hydroxy-e-homo-eburnanes
HU194220B (en) * 1985-04-19 1988-01-28 Richter Gedeon Vegyeszet Process for production of derivatives of 1,12 b disubstituated-octahydro-indolo /2,3-a/ quinolisine and medical compounds containing thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK139358B (da) * 1973-12-18 1979-02-05 Sandoz Ag Analogifremgangsmåde til fremstilling af vincaminderivater eller syreadditionssalte deraf.
HU175527B (hu) * 1977-03-28 1980-08-28 Richter Gedeon Vegyeszet Sposob dlja totalsinteze slozhnykh efirov apovinkaminnojj kisloty i gomologov
US4315011A (en) * 1978-07-12 1982-02-09 Richter Gedeon Vegyeszeti Gyar Rt. 1-Alkyl-9-bromohexahydroindolo quinolizium salts and use thereof to increase blood flow

Also Published As

Publication number Publication date
FR2444037A1 (fr) 1980-07-11
ES486799A1 (es) 1980-10-01
CH658059A5 (de) 1986-10-15
FR2444037B1 (fr) 1985-09-20
JPS5583784A (en) 1980-06-24
DE2950436A1 (de) 1980-07-10
GB2039900A (en) 1980-08-20

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Legal Events

Date Code Title Description
HU90 Patent valid on 900628
HMM4 Cancellation of final prot. due to non-payment of fee