HRP980496B1 - New thilozine hydroxy derivatives and a process for the preparation thereof - Google Patents
New thilozine hydroxy derivatives and a process for the preparation thereofInfo
- Publication number
- HRP980496B1 HRP980496B1 HR980496A HRP980496A HRP980496B1 HR P980496 B1 HRP980496 B1 HR P980496B1 HR 980496 A HR980496 A HR 980496A HR P980496 A HRP980496 A HR P980496A HR P980496 B1 HRP980496 B1 HR P980496B1
- Authority
- HR
- Croatia
- Prior art keywords
- thilozine
- preparation
- new
- hydroxy derivatives
- line
- Prior art date
Links
- 125000002887 hydroxy group Chemical group [H]O* 0.000 title 1
- WBPYTXDJUQJLPQ-VMXQISHHSA-N tylosin Chemical class O([C@@H]1[C@@H](C)O[C@H]([C@@H]([C@H]1N(C)C)O)O[C@@H]1[C@@H](C)[C@H](O)CC(=O)O[C@@H]([C@H](/C=C(\C)/C=C/C(=O)[C@H](C)C[C@@H]1CC=O)CO[C@H]1[C@@H]([C@H](OC)[C@H](O)[C@@H](C)O1)OC)CC)[C@H]1C[C@@](C)(O)[C@@H](O)[C@H](C)O1 WBPYTXDJUQJLPQ-VMXQISHHSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Seasonings (AREA)
- Steroid Compounds (AREA)
Priority Applications (19)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HR980496A HRP980496B1 (en) | 1998-09-10 | 1998-09-10 | New thilozine hydroxy derivatives and a process for the preparation thereof |
| CZ19993154A CZ294935B6 (cs) | 1998-09-10 | 1999-09-06 | 12,13-Dihydroxyderiváty tylosinu a způsob jejich výroby |
| SI9930319T SI0985679T1 (en) | 1998-09-10 | 1999-09-07 | New hydroxy derivatives of tylosin and process for their preparation |
| ES99117654T ES2198102T3 (es) | 1998-09-10 | 1999-09-07 | Nuevos derivados hidroxi de la tilosina y procedimiento para su preparacion. |
| EP99117654A EP0985679B8 (en) | 1998-09-10 | 1999-09-07 | New hydroxy derivatives of tylosin and process for their preparation |
| DK99117654T DK0985679T3 (da) | 1998-09-10 | 1999-09-07 | Nye hydroxyderivater af tylosin og fremgangsmåde til deres fremstilling |
| DE69907101T DE69907101T2 (de) | 1998-09-10 | 1999-09-07 | Neue Hydroxyderivate von Tylosin und Verfahren zu deren Herstellung |
| AT99117654T ATE238331T1 (de) | 1998-09-10 | 1999-09-07 | Neue hydroxyderivate von tylosin und verfahren zu deren herstellung |
| CA002281496A CA2281496C (en) | 1998-09-10 | 1999-09-09 | New hydroxy derivatives of tylosin and process for their preparation |
| NO19994366A NO312839B1 (no) | 1998-09-10 | 1999-09-09 | Nye hydroksyderivater av tylosin og fremgangsmåte for fremstilling av dem |
| UA99095030A UA66355C2 (en) | 1998-09-10 | 1999-09-09 | Hydroxy derivatives of tylosin and methods for the preparation thereof |
| RU99119585/04A RU2220149C2 (ru) | 1998-09-10 | 1999-09-09 | 12,13-дигидроксипроизводные тилозина, способ их получения |
| CNB991220617A CN1150202C (zh) | 1998-09-10 | 1999-09-10 | 新的泰乐菌素羟基衍生物及其制备方法 |
| JP11256906A JP2000086691A (ja) | 1998-09-10 | 1999-09-10 | チロシンの新規ヒドロキシ誘導体及びその製造方法 |
| SK1241-99A SK284841B6 (sk) | 1998-09-10 | 1999-09-10 | 12,13-Dihydroxyderiváty tylozínu a spôsob výroby |
| BG103726A BG64561B1 (bg) | 1998-09-10 | 1999-09-10 | Хидрокси производни на тилозин и метод за тяхното получаване |
| US09/393,322 US6211348B1 (en) | 1998-09-10 | 1999-09-10 | Hydroxy derivatives of tylosin and process for their preparation |
| HU9903063A HUP9903063A2 (hu) | 1998-09-10 | 1999-09-10 | Új tilozinszármazékok és eljárás előállításukra |
| PL335362A PL195483B1 (pl) | 1998-09-10 | 1999-09-10 | 12,13-dihydroksylowe pochodne tylozyny i sposób ich wytwarzania |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HR980496A HRP980496B1 (en) | 1998-09-10 | 1998-09-10 | New thilozine hydroxy derivatives and a process for the preparation thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HRP980496A2 HRP980496A2 (en) | 2000-04-30 |
| HRP980496B1 true HRP980496B1 (en) | 2007-03-31 |
Family
ID=10946806
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR980496A HRP980496B1 (en) | 1998-09-10 | 1998-09-10 | New thilozine hydroxy derivatives and a process for the preparation thereof |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US6211348B1 (zh) |
| EP (1) | EP0985679B8 (zh) |
| JP (1) | JP2000086691A (zh) |
| CN (1) | CN1150202C (zh) |
| AT (1) | ATE238331T1 (zh) |
| BG (1) | BG64561B1 (zh) |
| CA (1) | CA2281496C (zh) |
| CZ (1) | CZ294935B6 (zh) |
| DE (1) | DE69907101T2 (zh) |
| DK (1) | DK0985679T3 (zh) |
| ES (1) | ES2198102T3 (zh) |
| HR (1) | HRP980496B1 (zh) |
| HU (1) | HUP9903063A2 (zh) |
| NO (1) | NO312839B1 (zh) |
| PL (1) | PL195483B1 (zh) |
| RU (1) | RU2220149C2 (zh) |
| SI (1) | SI0985679T1 (zh) |
| SK (1) | SK284841B6 (zh) |
| UA (1) | UA66355C2 (zh) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7247617B2 (en) | 2004-07-13 | 2007-07-24 | Kosan Biosciences Incorporated | Sixteen-member macrolide antiinfective agents |
| WO2006073172A1 (ja) * | 2005-01-07 | 2006-07-13 | Meiji Seika Kaisha, Ltd. | 12-オキシ-13-アミノ含有16員環マクロライド誘導体及びその製造法 |
| FR2891835B1 (fr) * | 2005-10-11 | 2007-12-14 | Alchimer Sa | Procede de modification de surfaces de polymeres, notamment d'hydroxylation de surfaces de polymeres, et produits tels qu'obtenus |
| CN117510561B (zh) * | 2023-11-30 | 2024-04-02 | 中国农业科学院饲料研究所 | 一种泰乐菌素衍生物及其制备方法与应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU551142B2 (en) * | 1981-07-09 | 1986-04-17 | Zaidan Hojin Biseibutsu Kagaku Kenkyukai | Tylosin derivatives |
| US4454314A (en) * | 1982-08-02 | 1984-06-12 | Pfizer Inc. | Antibacterial mycaminosyl tylonolide and related macrolide derivatives |
| SI8710674B (sl) * | 1987-04-14 | 1998-06-30 | Pliva | Postopek za pripravo 10,11,12,13-tetrahidro derivatov tilozina |
| JP3063943B2 (ja) * | 1992-02-26 | 2000-07-12 | 明治製菓株式会社 | 血漿中において抗菌活性の持続する新規１６員環マクロリド誘導体及びその合成中間体とそれらの製造法 |
| HRP950449A2 (en) * | 1995-08-14 | 1997-12-31 | Nevenka Lopotar | Derivatives of 12, 13-epoxy-tylosin and processes of manufacture thereof |
| HRP960509A2 (en) * | 1996-10-30 | 1998-06-30 | Pliva Pharm & Chem Works | Novel polyhydro tylosin derivatives and a process for the preparation thereof |
-
1998
- 1998-09-10 HR HR980496A patent/HRP980496B1/xx not_active IP Right Cessation
-
1999
- 1999-09-06 CZ CZ19993154A patent/CZ294935B6/cs not_active IP Right Cessation
- 1999-09-07 ES ES99117654T patent/ES2198102T3/es not_active Expired - Lifetime
- 1999-09-07 DE DE69907101T patent/DE69907101T2/de not_active Expired - Lifetime
- 1999-09-07 EP EP99117654A patent/EP0985679B8/en not_active Expired - Lifetime
- 1999-09-07 SI SI9930319T patent/SI0985679T1/xx unknown
- 1999-09-07 DK DK99117654T patent/DK0985679T3/da active
- 1999-09-07 AT AT99117654T patent/ATE238331T1/de not_active IP Right Cessation
- 1999-09-09 NO NO19994366A patent/NO312839B1/no unknown
- 1999-09-09 UA UA99095030A patent/UA66355C2/uk unknown
- 1999-09-09 RU RU99119585/04A patent/RU2220149C2/ru not_active IP Right Cessation
- 1999-09-09 CA CA002281496A patent/CA2281496C/en not_active Expired - Fee Related
- 1999-09-10 JP JP11256906A patent/JP2000086691A/ja active Pending
- 1999-09-10 PL PL335362A patent/PL195483B1/pl unknown
- 1999-09-10 HU HU9903063A patent/HUP9903063A2/hu unknown
- 1999-09-10 CN CNB991220617A patent/CN1150202C/zh not_active Expired - Fee Related
- 1999-09-10 BG BG103726A patent/BG64561B1/bg unknown
- 1999-09-10 SK SK1241-99A patent/SK284841B6/sk unknown
- 1999-09-10 US US09/393,322 patent/US6211348B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN1250054A (zh) | 2000-04-12 |
| CZ294935B6 (cs) | 2005-04-13 |
| SK124199A3 (en) | 2000-12-11 |
| HUP9903063A2 (hu) | 2000-03-28 |
| CN1150202C (zh) | 2004-05-19 |
| DE69907101D1 (de) | 2003-05-28 |
| BG64561B1 (bg) | 2005-07-29 |
| NO994366L (no) | 2000-03-13 |
| CA2281496A1 (en) | 2000-03-10 |
| DE69907101T2 (de) | 2004-04-08 |
| CZ315499A3 (cs) | 2000-04-12 |
| US6211348B1 (en) | 2001-04-03 |
| CA2281496C (en) | 2005-11-01 |
| HRP980496A2 (en) | 2000-04-30 |
| EP0985679A1 (en) | 2000-03-15 |
| RU2220149C2 (ru) | 2003-12-27 |
| ATE238331T1 (de) | 2003-05-15 |
| PL335362A1 (en) | 2000-03-13 |
| NO312839B1 (no) | 2002-07-08 |
| ES2198102T3 (es) | 2004-01-16 |
| PL195483B1 (pl) | 2007-09-28 |
| UA66355C2 (en) | 2004-05-17 |
| EP0985679B1 (en) | 2003-04-23 |
| EP0985679B8 (en) | 2003-09-03 |
| SI0985679T1 (en) | 2003-10-31 |
| DK0985679T3 (da) | 2003-08-11 |
| BG103726A (en) | 2000-12-29 |
| SK284841B6 (sk) | 2005-12-01 |
| JP2000086691A (ja) | 2000-03-28 |
| NO994366D0 (no) | 1999-09-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A1OB | Publication of a patent application | ||
| AIPI | Request for the grant of a patent on the basis of a substantive examination of a patent application | ||
| PNAN | Change of the applicant name, address/residence |
Owner name: GLAXOSMITHKLINE ISTRAZIVACKI CENTAR ZAGREB D.O.O., |
|
| PPPP | Transfer of rights |
Owner name: PLIVA-ISTRAZIVACKI INSTITUT D.O.O., HR |
|
| B1PR | Patent granted | ||
| ODRP | Renewal fee for the maintenance of a patent |
Payment date: 20070905 Year of fee payment: 10 |
|
| PBON | Lapse due to non-payment of renewal fee |
Effective date: 20080911 |