HRP940933A2

HRP940933A2 - Process for the preparation of capsule body

Info

Publication number: HRP940933A2
Application number: HRP-1501/82A
Authority: HR
Inventors: Hans Ulrich Bodenmann; Lou Van Herle; Winand Martens
Original assignee: Parke Davis & Co
Priority date: 1977-05-20
Filing date: 1994-11-16
Publication date: 1997-06-30

Description

Izum se odnosi na postupak za izradu tijela kapsule, koja ima uglavnom oblik na jednom kraju zatvorenog valjka, osobito za zaštićenu kapsulu za lijekove prema patentnu br. (patentna prijava br. P 1216/78). Po tom postupku koristi se potopni zatik koji se potopi u kupelj tekućine koja se skrućuje i pri tome oblikuje stijenku tijela kapsule. The invention relates to a process for producing a capsule body, which has the shape of a closed roller at one end, in particular for a protected medicine capsule according to patent no. (patent application no. P 1216/78). According to this procedure, an immersion pin is used, which is immersed in a bath of liquid that solidifies and in the process forms the wall of the capsule body.

Tijelo kapsule prema patentu br. (patentna prijava br. P 1216/78) izrađuje se ponajprije po uvodno opisanom postupku, koje se prema izumu dalje oblikuje tako da se najprije oblikuje tijelo kapsule povećane duljine, sa suženjem u području svojeg kasnije otvorenog kraja i zatim se prereze u području suženja. Tijelo kapsule korisno je nadalje prerezati na onom mjestu gdje suženje ima najmanji promjer. Time se, pri datoj dubini suženja, postiže najmanji mogući promjer gotovog tijela kapsule na njegovom slobodnom kraju. Capsule body according to patent no. (patent application no. P 1216/78) is made primarily according to the procedure described in the introduction, which according to the invention is further shaped so that the body of the capsule of increased length is first formed, with a narrowing in the area of its later open end and then it is cut in the narrowing area. It is useful to further cut the body of the capsule at the point where the constriction has the smallest diameter. This achieves, at a given taper depth, the smallest possible diameter of the finished capsule body at its free end.

Osna širina produljenja je ponajprije otprilike 10 do 20 puta veća od njene osne duljine. Kod takovog dimenzioniranja tijelo kapsule otvrduto na potopnom zatiku može se povući s potopnog zatika bez opasnosti da se tijelo kapsule u produljenju, gdje se kod povlačenja s potopnog zatika mora proširiti, mehanički preoptereti i potrga. The axial width of the extension is preferably approximately 10 to 20 times greater than its axial length. With such dimensioning, the body of the capsule hardened on the immersion pin can be withdrawn from the immersion pin without the risk that the capsule body in the extension, where it must expand during withdrawal from the immersion pin, is mechanically overloaded and torn.

Izum će se u nastavku objasniti na osnovi primjera s crtežima i s daljnjim pojedinostima, gdje slike l do 5 prikazuju razne stupnjeve postupka izrade tijela kapsule. Na slici 1 kupelj 10 je tekućina koja se skrućuje, na primjer želatina, i u njoj je potopljen zatik 12, koji ima zaobljen donji kraj i prstenasto kružno produljenje 14. Potopni zatik 12, zajedno s brojnim drugim potopnim zaticima, koji su svi međusobno jednaki, namazu se pomoću poznate i stoga neprikazane naprave i zatim se oni potope u kupelj 10 sve do iznad produljenja 14. The invention will be explained below by way of example with the drawings and with further details, where Figures 1 to 5 show the various stages of the process of making the capsule body. In Fig. 1, the bath 10 is a solidifying liquid, for example gelatin, and immersed in it is a pin 12, which has a rounded lower end and an annular circular extension 14. The immersion pin 12, together with numerous other immersion pins, which are all identical to each other, they are smeared using a known and therefore not shown device and then they are immersed in the bath 10 up to above the extension 14.

Kod izvlačenja potopnog zatika 12 iz kupelji 10 na njemu ostane sloj skrućujuće tekućine. Da bi taj sloj zadržao približno jednaku debljinu, dok se tekućina još nije skrutila toliko da više ne teče, potopni zatik 12 okreće se oko poprečne osi pomoću već poznate naprave, tako da je njegov na slici 2 donji kraj u jednom trenutku gore i u slijedećem trenutku je dolje. When the immersion plug 12 is pulled out of the bath 10, a layer of solidifying liquid remains on it. In order to keep this layer approximately the same thickness, while the liquid has not yet solidified so much that it no longer flows, the submersible pin 12 is rotated around the transverse axis by means of an already known device, so that its lower end in Figure 2 is at one moment up and at the next moment is down.

Kako se sloj 16 brzo skrutne, potopni zatik 12 se upne u dno ili višedijelnu patronu, čiji se dijelovi 20, 22 pomiču jedan prema drugom tako, da radijalno obuhvaćaju skrutnuti sloj 16. Zatim se, prema slici 4, povuče potopni zatik 12 iz patrone 18 prema gore tako, da sloj 16 ostane u patroni 18 kao odmaknuto tijelo 24. Produljenje 14 u potopnom zatiku dimenzionirano je tako da se potopni zatik 12 može povući iz plašta 16, koji predstavlja udaljeno tijelo 24, tako da se oblikovani spojeni prihvat suženja 26 tijela 24 u produljenju 14 potopnog zatika 12 ne odupire izvlačenju zatika 12. Pri tome su, s obzirom na duljinu tijela 24, mogući različiti rasponi dimenzioniranja. Kod potopnog zatika 12 s promjerom 6,7 mm produljenje 14 ima, na primjer, osnu duljinu otprilike 1,5 mm i dubinu otprilike 0,09 mm. Čeona ploha patrone 18 je ravna i podudara se s najdubljom točkom suženja 26. Nakon izvlačenja potopnog zatika 12, udaljeno tijelo 24 prereze se s nožem 28 na najdubljem mjestu suženja 26, pri čemu se patronu 18 s tijelom 24 okreće oko uzdužne osi. Radijalnim razmicanjem dijelova 20 ili 22 patrone 18 oslobađa se izrađeno tijelo (vidi sliku 5) 30, koje ima smanjeni promjer u području 32 svojeg otvorenog kraja. As the layer 16 solidifies quickly, the immersion pin 12 is clamped into the bottom or multi-part cartridge, the parts 20, 22 of which move towards each other so as to radially encompass the solidified layer 16. Then, according to Figure 4, the immersion pin 12 is withdrawn from the cartridge 18 upwards so that the layer 16 remains in the cartridge 18 as a spaced body 24. The extension 14 in the submersible pin is dimensioned so that the submersible pin 12 can be withdrawn from the jacket 16, which represents the remote body 24, so that the molded joint taper receptacle 26 the body 24 in the extension 14 of the submersible pin 12 does not resist the withdrawal of the pin 12. At the same time, considering the length of the body 24, different dimensioning ranges are possible. In a 6.7 mm diameter countersunk pin 12, the extension 14 has, for example, an axial length of approximately 1.5 mm and a depth of approximately 0.09 mm. The front surface of the cartridge 18 is flat and coincides with the deepest point of the taper 26. After pulling out the submersible pin 12, the remote body 24 is cut with a knife 28 at the deepest point of the taper 26, whereby the cartridge 18 with the body 24 is rotated about the longitudinal axis. Radial separation of the parts 20 or 22 of the cartridge 18 releases the manufactured body (see Figure 5) 30, which has a reduced diameter in the area 32 of its open end.

Claims

1. A process for producing a capsule body, which has the shape of an open cylinder at one end according to patent number (patent application no. P 1216/78), especially plug-in capsules for drugs, which consist of a capsule body and a cap that is attached to it, characterized in that the body of the capsule (3) is made first with an extension (24) and with a narrowing (26) in the area (32) of its later open end and then in the area of the narrowing (26) it is cut with a knife (28).

2. The method according to claim 1, characterized in that the elongated body (24) of the capsule is cut to the length of the body (30) where the constriction (26) has the smallest diameter.