HRP20220722T1 - Poboljšano hvatanje rnk interaktoma (eric) - Google Patents
Poboljšano hvatanje rnk interaktoma (eric) Download PDFInfo
- Publication number
- HRP20220722T1 HRP20220722T1 HRP20220722TT HRP20220722T HRP20220722T1 HR P20220722 T1 HRP20220722 T1 HR P20220722T1 HR P20220722T T HRP20220722T T HR P20220722TT HR P20220722 T HRP20220722 T HR P20220722T HR P20220722 T1 HRP20220722 T1 HR P20220722T1
- Authority
- HR
- Croatia
- Prior art keywords
- rbps
- oligonucleotide
- rna
- complexes
- lna
- Prior art date
Links
- 102000044126 RNA-Binding Proteins Human genes 0.000 claims 12
- 108700020471 RNA-Binding Proteins Proteins 0.000 claims 12
- 238000000034 method Methods 0.000 claims 12
- 108091034117 Oligonucleotide Proteins 0.000 claims 7
- 108091032973 (ribonucleotides)n+m Proteins 0.000 claims 4
- 239000012620 biological material Substances 0.000 claims 3
- 230000029087 digestion Effects 0.000 claims 3
- 125000002652 ribonucleotide group Chemical group 0.000 claims 3
- 239000000872 buffer Substances 0.000 claims 2
- 230000000295 complement effect Effects 0.000 claims 2
- 238000010828 elution Methods 0.000 claims 2
- KWGKDLIKAYFUFQ-UHFFFAOYSA-M lithium chloride Chemical compound [Li+].[Cl-] KWGKDLIKAYFUFQ-UHFFFAOYSA-M 0.000 claims 2
- 108020004707 nucleic acids Proteins 0.000 claims 2
- 102000039446 nucleic acids Human genes 0.000 claims 2
- 239000002773 nucleotide Substances 0.000 claims 2
- 238000002360 preparation method Methods 0.000 claims 2
- 230000005855 radiation Effects 0.000 claims 2
- 239000000523 sample Substances 0.000 claims 2
- 239000007787 solid Substances 0.000 claims 2
- 102000004190 Enzymes Human genes 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 238000004458 analytical method Methods 0.000 claims 1
- 238000005119 centrifugation Methods 0.000 claims 1
- 239000003153 chemical reaction reagent Substances 0.000 claims 1
- 239000013068 control sample Substances 0.000 claims 1
- 238000004132 cross linking Methods 0.000 claims 1
- 238000001514 detection method Methods 0.000 claims 1
- 230000002255 enzymatic effect Effects 0.000 claims 1
- 238000002955 isolation Methods 0.000 claims 1
- YFVGRULMIQXYNE-UHFFFAOYSA-M lithium;dodecyl sulfate Chemical compound [Li+].CCCCCCCCCCCCOS([O-])(=O)=O YFVGRULMIQXYNE-UHFFFAOYSA-M 0.000 claims 1
- 230000002934 lysing effect Effects 0.000 claims 1
- 239000006249 magnetic particle Substances 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 238000010833 quantitative mass spectrometry Methods 0.000 claims 1
- 238000010008 shearing Methods 0.000 claims 1
- 239000007790 solid phase Substances 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP17186948 | 2017-08-18 | ||
| EP18756423.2A EP3669193B1 (en) | 2017-08-18 | 2018-08-17 | Enhanced rna interactome capture (eric) |
| PCT/EP2018/072348 WO2019034783A1 (en) | 2017-08-18 | 2018-08-17 | IMPROVED RNA INTERACTOME CAPTURE (ERIC) |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20220722T1 true HRP20220722T1 (hr) | 2022-07-22 |
Family
ID=59702542
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HRP20220722TT HRP20220722T1 (hr) | 2017-08-18 | 2018-08-17 | Poboljšano hvatanje rnk interaktoma (eric) |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US12117437B2 (https=) |
| EP (1) | EP3669193B1 (https=) |
| JP (1) | JP7313696B2 (https=) |
| CN (1) | CN110998332B (https=) |
| AU (1) | AU2018316551B2 (https=) |
| DK (1) | DK3669193T3 (https=) |
| ES (1) | ES2921301T3 (https=) |
| HR (1) | HRP20220722T1 (https=) |
| HU (1) | HUE059038T2 (https=) |
| PL (1) | PL3669193T3 (https=) |
| PT (1) | PT3669193T (https=) |
| RS (1) | RS63423B1 (https=) |
| WO (1) | WO2019034783A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110205365B (zh) * | 2019-07-02 | 2023-07-25 | 中山大学孙逸仙纪念医院 | 一种高效研究rna相互作用组的高通量测序方法及其应用 |
| GB202101188D0 (en) * | 2021-01-28 | 2021-03-17 | Cambridge Entpr Ltd | Method |
| WO2024097262A1 (en) * | 2022-10-31 | 2024-05-10 | University Of Virginia Patent Foundation | Chemoproteomic capture of rna binding activity in living cells |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU9063398A (en) * | 1997-09-12 | 1999-04-05 | Exiqon A/S | Oligonucleotide analogues |
| RU2377301C2 (ru) * | 2003-12-23 | 2009-12-27 | Сантарис Фарма А/С | ОЛИГОМЕРНОЕ СОЕДИНЕНИЕ, ПОНИЖАЮЩЕЕ ЭКСПРЕССИЮ ЧЕЛОВЕЧЕСКОГО ГЕНА Bcl-2, КОНЪЮГАТ, ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ И ПРИМЕНЕНИЕ ОЛИГОМЕРНОГО СОЕДИНЕНИЯ ДЛЯ ЛЕЧЕНИЯ РАКА |
| AU2008290376B2 (en) | 2007-08-20 | 2014-05-08 | The General Hospital Corporation | Isolation of protein factors that associate directly or indirectly with nucleic acids |
| US8748354B2 (en) | 2011-08-09 | 2014-06-10 | The Board Of Trustees Of The Leland Stanford Junior University | RNA interactome analysis |
| EP3102612B1 (en) | 2014-02-07 | 2024-10-09 | European Molecular Biology Laboratory | Proteomic sample preparation using paramagnetic beads |
| WO2015191780A2 (en) | 2014-06-10 | 2015-12-17 | The General Hospital Corporation | Ccctc-binding factor (ctcf) rna interactome |
| WO2016149455A2 (en) | 2015-03-17 | 2016-09-22 | The General Hospital Corporation | The rna interactome of polycomb repressive complex 1 (prc1) |
-
2018
- 2018-08-17 DK DK18756423.2T patent/DK3669193T3/da active
- 2018-08-17 CN CN201880053251.2A patent/CN110998332B/zh active Active
- 2018-08-17 HU HUE18756423A patent/HUE059038T2/hu unknown
- 2018-08-17 WO PCT/EP2018/072348 patent/WO2019034783A1/en not_active Ceased
- 2018-08-17 JP JP2020509047A patent/JP7313696B2/ja active Active
- 2018-08-17 PL PL18756423.2T patent/PL3669193T3/pl unknown
- 2018-08-17 PT PT187564232T patent/PT3669193T/pt unknown
- 2018-08-17 ES ES18756423T patent/ES2921301T3/es active Active
- 2018-08-17 US US16/639,795 patent/US12117437B2/en active Active
- 2018-08-17 HR HRP20220722TT patent/HRP20220722T1/hr unknown
- 2018-08-17 EP EP18756423.2A patent/EP3669193B1/en active Active
- 2018-08-17 RS RS20220632A patent/RS63423B1/sr unknown
- 2018-08-17 AU AU2018316551A patent/AU2018316551B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| ES2921301T3 (es) | 2022-08-23 |
| EP3669193B1 (en) | 2022-04-06 |
| RS63423B1 (sr) | 2022-08-31 |
| JP2020536491A (ja) | 2020-12-17 |
| HUE059038T2 (hu) | 2022-10-28 |
| CN110998332A (zh) | 2020-04-10 |
| WO2019034783A1 (en) | 2019-02-21 |
| PT3669193T (pt) | 2022-07-06 |
| JP7313696B2 (ja) | 2023-07-25 |
| CA3073297A1 (en) | 2019-02-21 |
| AU2018316551A1 (en) | 2020-03-05 |
| AU2018316551B2 (en) | 2024-12-05 |
| EP3669193A1 (en) | 2020-06-24 |
| US20200209228A1 (en) | 2020-07-02 |
| CN110998332B (zh) | 2024-04-09 |
| PL3669193T3 (pl) | 2022-07-25 |
| DK3669193T3 (da) | 2022-07-11 |
| US12117437B2 (en) | 2024-10-15 |
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