HRP20180485T1 - Monoklonska antitijela za gt468 za liječenje raka - Google Patents

Monoklonska antitijela za gt468 za liječenje raka

Info

Publication number
HRP20180485T1
HRP20180485T1 HRP20180485TT HRP20180485T HRP20180485T1 HR P20180485 T1 HRP20180485 T1 HR P20180485T1 HR P20180485T T HRP20180485T T HR P20180485TT HR P20180485 T HRP20180485 T HR P20180485T HR P20180485 T1 HRP20180485 T1 HR P20180485T1
Authority
HR
Croatia
Prior art keywords
cancer
treatment
monoclonal antibodies
monoclonal
antibodies
Prior art date
Application number
HRP20180485TT
Other languages
English (en)
Inventor
Ugur Sahin
Michael Koslowski
Özlem TÜRECI
Original Assignee
Ganymed Pharmaceuticals Gmbh
Johannes Gutenberg-Universität Mainz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ganymed Pharmaceuticals Gmbh, Johannes Gutenberg-Universität Mainz filed Critical Ganymed Pharmaceuticals Gmbh
Publication of HRP20180485T1 publication Critical patent/HRP20180485T1/hr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732Antibody-dependent cellular cytotoxicity [ADCC]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/734Complement-dependent cytotoxicity [CDC]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Reproductive Health (AREA)
HRP20180485TT 2007-03-14 2018-03-23 Monoklonska antitijela za gt468 za liječenje raka HRP20180485T1 (hr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US89486007P 2007-03-14 2007-03-14
EP07005258A EP1970384A1 (en) 2007-03-14 2007-03-14 Monoclonal antibodies for treatment of cancer
EP08734614.4A EP2125897B1 (en) 2007-03-14 2008-03-14 Monoclonal antibodies against gt468 for treatment of cancer
PCT/EP2008/002063 WO2008110379A2 (en) 2007-03-14 2008-03-14 Monoclonal antibodies for treatment of cancer

Publications (1)

Publication Number Publication Date
HRP20180485T1 true HRP20180485T1 (hr) 2018-05-18

Family

ID=38134942

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20180485TT HRP20180485T1 (hr) 2007-03-14 2018-03-23 Monoklonska antitijela za gt468 za liječenje raka

Country Status (25)

Country Link
US (4) US8354104B2 (hr)
EP (3) EP1970384A1 (hr)
JP (2) JP5389675B2 (hr)
KR (2) KR20150080032A (hr)
CN (2) CN105131115A (hr)
AU (1) AU2008226001B2 (hr)
BR (1) BRPI0808814A2 (hr)
CA (1) CA2678732C (hr)
CY (1) CY1120123T1 (hr)
DK (1) DK2125897T3 (hr)
ES (1) ES2664571T3 (hr)
HR (1) HRP20180485T1 (hr)
HU (1) HUE037671T2 (hr)
IL (1) IL200388A (hr)
LT (1) LT2125897T (hr)
MX (1) MX2009009816A (hr)
NO (1) NO2125897T3 (hr)
NZ (1) NZ579614A (hr)
PL (1) PL2125897T3 (hr)
PT (1) PT2125897T (hr)
RS (1) RS57089B1 (hr)
SG (1) SG10201506625VA (hr)
SI (1) SI2125897T1 (hr)
WO (1) WO2008110379A2 (hr)
ZA (1) ZA200905833B (hr)

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EP1762575A1 (en) 2005-09-12 2007-03-14 Ganymed Pharmaceuticals AG Identification of tumor-associated antigens for diagnosis and therapy
EP1970384A1 (en) 2007-03-14 2008-09-17 Ganymed Pharmaceuticals AG Monoclonal antibodies for treatment of cancer
EP2166021A1 (en) * 2008-09-16 2010-03-24 Ganymed Pharmaceuticals AG Monoclonal antibodies for treatment of cancer
AU2015205868B2 (en) * 2008-09-16 2017-04-27 Ganymed Pharmaceuticals Ag Monoclonal antibodies for treatment of cancer
EP2371864A1 (en) * 2010-03-23 2011-10-05 Ganymed Pharmaceuticals AG Monoclonal antibodies for treatment of cancer
DK3026064T3 (en) 2011-05-13 2019-01-14 Ganymed Pharmaceuticals Gmbh ANTIBODIES FOR TREATMENT OF CANCER EXPRESSING CLAUDIN 6
WO2014146672A1 (en) * 2013-03-18 2014-09-25 Ganymed Pharmaceuticals Ag Therapy involving antibodies against claudin 18.2 for treatment of cancer
CN106659785B (zh) * 2014-05-07 2021-04-30 武田有限公司 包含gm-csf中和化合物的液体制剂
CN108779497B (zh) * 2016-03-14 2022-08-02 库雷梅塔治疗有限责任公司 足糖萼蛋白和tra-相关抗体、制备方法和作为抗癌治疗剂的用途
TW201900213A (zh) * 2017-05-27 2019-01-01 美商免疫醫療公司 免疫球蛋白a陽性細胞的調節
WO2023220336A1 (en) * 2022-05-13 2023-11-16 Herzlinger Regina E Methods, systems, and apparatus for administering an antibody treatment via infusion

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Also Published As

Publication number Publication date
US10125196B2 (en) 2018-11-13
SI2125897T1 (en) 2018-06-29
JP2010520910A (ja) 2010-06-17
SG10201506625VA (en) 2015-10-29
US9475867B2 (en) 2016-10-25
DK2125897T3 (en) 2018-04-23
NZ579614A (en) 2012-02-24
CA2678732A1 (en) 2008-09-18
RS57089B1 (sr) 2018-06-29
KR20150080032A (ko) 2015-07-08
WO2008110379A8 (en) 2009-11-05
AU2008226001B2 (en) 2013-09-05
US20100111975A1 (en) 2010-05-06
KR101567494B1 (ko) 2015-11-23
AU2008226001A1 (en) 2008-09-18
JP5389675B2 (ja) 2014-01-15
NO2125897T3 (hr) 2018-06-16
LT2125897T (lt) 2018-04-25
CA2678732C (en) 2017-12-19
CN101754979A (zh) 2010-06-23
US20130156782A1 (en) 2013-06-20
ES2664571T3 (es) 2018-04-20
EP2125897A2 (en) 2009-12-02
WO2008110379A3 (en) 2008-10-30
ZA200905833B (en) 2011-02-23
PT2125897T (pt) 2018-03-29
EP1970384A1 (en) 2008-09-17
JP2013255506A (ja) 2013-12-26
CN105131115A (zh) 2015-12-09
BRPI0808814A2 (pt) 2015-06-23
MX2009009816A (es) 2009-11-23
CN101754979B (zh) 2015-04-08
IL200388A0 (en) 2010-04-29
CY1120123T1 (el) 2018-12-12
EP2487189A1 (en) 2012-08-15
JP5843822B2 (ja) 2016-01-13
EP2487189B1 (en) 2018-08-22
IL200388A (en) 2015-08-31
EP2487189B8 (en) 2019-01-09
US20170058044A1 (en) 2017-03-02
HUE037671T2 (hu) 2018-09-28
US8961980B2 (en) 2015-02-24
US20150175686A1 (en) 2015-06-25
KR20100014405A (ko) 2010-02-10
US8354104B2 (en) 2013-01-15
WO2008110379A2 (en) 2008-09-18
EP2125897B1 (en) 2018-01-17
PL2125897T3 (pl) 2018-09-28

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