HRP20171651T1 - (s)-pirlindol i njegove farmaceutski prihvatljive soli za uporabu u medicini - Google Patents

(s)-pirlindol i njegove farmaceutski prihvatljive soli za uporabu u medicini Download PDF

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Publication number
HRP20171651T1
HRP20171651T1 HRP20171651TT HRP20171651T HRP20171651T1 HR P20171651 T1 HRP20171651 T1 HR P20171651T1 HR P20171651T T HRP20171651T T HR P20171651TT HR P20171651 T HRP20171651 T HR P20171651T HR P20171651 T1 HRP20171651 T1 HR P20171651T1
Authority
HR
Croatia
Prior art keywords
pyrlindole
pharmaceutically acceptable
enantiomer
acceptable salt
use according
Prior art date
Application number
HRP20171651TT
Other languages
English (en)
Croatian (hr)
Inventor
Augusto Eugénio PARDAL FILIPE
Pedro Filipe EUFRÁSIO PEDROSO
Susana Marques ALMEIDA PECORELLI
Carlos Alberto Eufrásio CASIMIRO CAIXADO
Ana Sofia da Conceição LOPES
João Carlos DAMIL
Original Assignee
Tecnimede-Sociedade Tecnico-Medicinal, S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tecnimede-Sociedade Tecnico-Medicinal, S.A. filed Critical Tecnimede-Sociedade Tecnico-Medicinal, S.A.
Publication of HRP20171651T1 publication Critical patent/HRP20171651T1/hr

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • A61K9/2018Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Indole Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Furan Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
HRP20171651TT 2014-05-09 2014-05-09 (s)-pirlindol i njegove farmaceutski prihvatljive soli za uporabu u medicini HRP20171651T1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/PT2014/000029 WO2015171005A1 (en) 2014-05-09 2014-05-09 (s)-pirlindole or its pharmaceutically acceptable salts for use in medicine
EP14726444.4A EP3057589B1 (en) 2014-05-09 2014-05-09 (s)-pirlindole or its pharmaceutically acceptable salts for use in medicine

Publications (1)

Publication Number Publication Date
HRP20171651T1 true HRP20171651T1 (hr) 2017-12-15

Family

ID=50819931

Family Applications (1)

Application Number Title Priority Date Filing Date
HRP20171651TT HRP20171651T1 (hr) 2014-05-09 2014-05-09 (s)-pirlindol i njegove farmaceutski prihvatljive soli za uporabu u medicini

Country Status (30)

Country Link
US (1) US9814712B2 (enExample)
EP (1) EP3057589B1 (enExample)
JP (1) JP6768520B2 (enExample)
KR (1) KR102298676B1 (enExample)
CN (1) CN106456637B (enExample)
AU (1) AU2014393490B2 (enExample)
CA (1) CA2948598C (enExample)
CY (1) CY1119532T1 (enExample)
DK (1) DK3057589T3 (enExample)
EC (1) ECSP16086247A (enExample)
ES (1) ES2649492T3 (enExample)
HR (1) HRP20171651T1 (enExample)
HU (1) HUE035071T2 (enExample)
IL (1) IL248855B (enExample)
LT (1) LT3057589T (enExample)
MA (1) MA39447B1 (enExample)
MX (1) MX368734B (enExample)
NO (1) NO3057589T3 (enExample)
NZ (1) NZ726132A (enExample)
PH (1) PH12016502233A1 (enExample)
PL (1) PL3057589T3 (enExample)
PT (1) PT3057589T (enExample)
RS (1) RS56591B1 (enExample)
RU (1) RU2695647C2 (enExample)
SA (1) SA516380264B1 (enExample)
SI (1) SI3057589T1 (enExample)
SM (1) SMT201700519T1 (enExample)
TN (1) TN2016000498A1 (enExample)
UA (1) UA118474C2 (enExample)
WO (1) WO2015171005A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI3831385T3 (fi) * 2014-05-09 2024-09-04 Tecnimede Sociedade Tecnico Medicinal S Pirlindolienantiomeerien mandelaattisuoloja käytettäviksi lääkinnässä
NZ726131A (en) 2014-05-09 2018-12-21 Tecnimede Sociedade Tecnico Medicinal S (r)-pirlindole and its pharmaceutically acceptable salts for use in medicine
EP3392250A1 (en) 2017-04-21 2018-10-24 Tecnimede-Sociedade Tecnico-Medicinal, S.A. Process for the preparation of piperazine ring for the synthesis of pyrazinocarbazole derivatives
EP3392251A1 (en) 2017-04-21 2018-10-24 Tecnimede-Sociedade Tecnico-Medicinal, S.A. Process for the preparation of pirlindole enantiomers and its salts
MX2018011142A (es) 2018-09-13 2019-10-10 Federico Amezcua Amezcua Combinacion farmaceutica sinergica de un inhibidor selectivo de la ciclooxigenasa 2 y un derivado de antraquinona.
EP3900716A1 (en) * 2020-04-21 2021-10-27 Dompe' Farmaceutici S.P.A. Co-crystal of gabapentin, ketoprofen and lysine, pharmaceutical compositions and their medical use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1558231A4 (en) * 2002-10-03 2010-09-08 Cypress Bioscience Inc DOSAGE CLIMBING AND FRICTIONAL DAILY DOSE OF ANTIDEPRESSANTS TO TREAT NEUROLOGICAL DISORDERS
CA2511599A1 (en) * 2002-12-24 2004-07-15 Neurochem (International) Limited Therapeutic formulations for the treatment of beta-amyloid related diseases
EP1663180A1 (en) * 2003-09-15 2006-06-07 Vectura Limited Pharmaceutical compositions for treating premature ejaculation by pulmonary inhalation
EP1688161A1 (en) * 2004-11-02 2006-08-09 Switch Biotech Aktiengesellschaft Use of pirlindole for the treatment of diseases which are characterized by proliferation of t-lymphocytes and/or hyperproliferation of keratinocytes in particular atopic dermatitis and psoriasis
FI3831385T3 (fi) * 2014-05-09 2024-09-04 Tecnimede Sociedade Tecnico Medicinal S Pirlindolienantiomeerien mandelaattisuoloja käytettäviksi lääkinnässä

Also Published As

Publication number Publication date
MA39447B1 (fr) 2018-05-31
PL3057589T3 (pl) 2018-01-31
RU2695647C2 (ru) 2019-07-25
SMT201700519T1 (it) 2018-01-11
ES2649492T3 (es) 2018-01-12
CN106456637A (zh) 2017-02-22
CY1119532T1 (el) 2018-03-07
JP6768520B2 (ja) 2020-10-14
KR102298676B1 (ko) 2021-09-07
IL248855A0 (en) 2017-01-31
EP3057589A1 (en) 2016-08-24
CN106456637B (zh) 2020-06-09
MX368734B (es) 2019-10-14
PH12016502233A1 (en) 2017-02-06
RU2016148183A (ru) 2018-06-13
US20170143709A1 (en) 2017-05-25
WO2015171005A1 (en) 2015-11-12
AU2014393490A1 (en) 2016-11-24
CA2948598C (en) 2021-06-08
CA2948598A1 (en) 2015-11-12
SI3057589T1 (sl) 2017-12-29
US9814712B2 (en) 2017-11-14
AU2014393490B2 (en) 2020-01-02
RU2016148183A3 (enExample) 2018-06-13
SA516380264B1 (ar) 2019-07-29
KR20170002434A (ko) 2017-01-06
DK3057589T3 (da) 2017-11-13
LT3057589T (lt) 2017-11-27
PT3057589T (pt) 2017-11-29
JP2017518979A (ja) 2017-07-13
MX2016014699A (es) 2017-05-02
UA118474C2 (uk) 2019-01-25
NZ726132A (en) 2019-02-22
NO3057589T3 (enExample) 2017-12-30
ECSP16086247A (es) 2017-02-24
EP3057589B1 (en) 2017-08-02
RS56591B1 (sr) 2018-02-28
HUE035071T2 (en) 2018-05-02
MA39447A1 (fr) 2017-10-31
TN2016000498A1 (en) 2018-04-04
IL248855B (en) 2020-05-31

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