HRP20100137T1 - Spinozini, namijenjeni za zacjeljivanje rana - Google Patents
Spinozini, namijenjeni za zacjeljivanje rana Download PDFInfo
- Publication number
- HRP20100137T1 HRP20100137T1 HR20100137T HRP20100137T HRP20100137T1 HR P20100137 T1 HRP20100137 T1 HR P20100137T1 HR 20100137 T HR20100137 T HR 20100137T HR P20100137 T HRP20100137 T HR P20100137T HR P20100137 T1 HRP20100137 T1 HR P20100137T1
- Authority
- HR
- Croatia
- Prior art keywords
- salt
- physiologically acceptable
- spinosin
- intended
- demethylated derivative
- Prior art date
Links
- 230000029663 wound healing Effects 0.000 title claims abstract 3
- 229930185156 spinosyn Natural products 0.000 title 1
- 150000003839 salts Chemical class 0.000 claims abstract 11
- 241000124008 Mammalia Species 0.000 claims abstract 6
- VAKIESMDOCVMDV-HNNXBMFYSA-N Spinosine Chemical compound C1C2=CC(O)=C(O)C=C2C[C@@H]2N1CCC1=C2C=C(OC)C(OC)=C1 VAKIESMDOCVMDV-HNNXBMFYSA-N 0.000 claims abstract 3
- 230000001737 promoting effect Effects 0.000 claims abstract 2
- VGGSULWDCMWZPO-ODEMIOGVSA-N spinosin Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1C1=C(O)C=2C(=O)C=C(OC=2C=C1OC)C=1C=CC(O)=CC=1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O VGGSULWDCMWZPO-ODEMIOGVSA-N 0.000 claims 14
- VGGSULWDCMWZPO-UHFFFAOYSA-N flavoayamenin Natural products COC1=CC=2OC(C=3C=CC(O)=CC=3)=CC(=O)C=2C(O)=C1C1OC(CO)C(O)C(O)C1OC1OC(CO)C(O)C(O)C1O VGGSULWDCMWZPO-UHFFFAOYSA-N 0.000 claims 7
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 208000035475 disorder Diseases 0.000 claims 2
- 230000035876 healing Effects 0.000 claims 2
- JFLRKDZMHNBDQS-UCQUSYKYSA-N CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@H]3[C@@H]4C[C@@H](C[C@H]4C(=C[C@H]3[C@@H]2CC(=O)O1)C)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C.CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@H]3[C@@H]4C[C@@H](C[C@H]4C=C[C@H]3C2CC(=O)O1)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C Chemical group CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@H]3[C@@H]4C[C@@H](C[C@H]4C(=C[C@H]3[C@@H]2CC(=O)O1)C)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C.CC[C@H]1CCC[C@@H]([C@H](C(=O)C2=C[C@H]3[C@@H]4C[C@@H](C[C@H]4C=C[C@H]3C2CC(=O)O1)O[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)OC)OC)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)N(C)C JFLRKDZMHNBDQS-UCQUSYKYSA-N 0.000 claims 1
- 241001494479 Pecora Species 0.000 claims 1
- 239000005930 Spinosad Substances 0.000 claims 1
- 206010052428 Wound Diseases 0.000 claims 1
- 208000027418 Wounds and injury Diseases 0.000 claims 1
- 229940014213 spinosad Drugs 0.000 claims 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Abstract
Spinozin, ili njegov fiziološki prihvatljiv N-demetilirani derivat ili njegova sol, naznačen time što je namijenjen upotrebi u poticanju ubrzanog zacjeljivanja rana kod sisavca. Patent sadrži još 8 patentnih zahtjeva.
Claims (9)
1. Spinozin, ili njegov fiziološki prihvatljiv N-demetilirani derivat ili njegova sol, naznačen time što je namijenjen upotrebi u poticanju ubrzanog zacjeljivanja rana kod sisavca.
2. Spinozin, ili njegov fiziološki prihvatljiv N-demetilirani derivat ili njegova sol, namijenjen upotrebi u skladu s patentnim zahtjevom 1, naznačen time što navedeni spinozin je spinozad, ili njegov fiziološki prihvatljiv N-demetilirani derivat ili njegova sol.
3. Spinozin, ili njegov fiziološki prihvatljiv N-demetilirani derivat ili njegova sol, namijenjen upotrebi u skladu s patentnim zahtjevom 1 ili patentnim zahtjevom 2, naznačen time što navedeni sisavac nema poremećaj zacjeljivanja.
4. Spinozin, ili njegov fiziološki prihvatljiv N-demetilirani derivat ili njegova sol, namijenjen upotrebi u skladu s patentnim zahtjevom 1 ili patentnim zahtjevom 2, naznačen time što navedeni sisavac ima poremećaj zacjeljivanja.
5. Spinozin, ili njegov fiziološki prihvatljiv N-demetilirani derivat ili njegova sol, namijenjen upotrebi u skladu s bilo kojim patentnim zahtjevom od 1 do 4, naznačen time što navedeni spinozin se primjenjuje topikalno, na navedenu ranu.
6. Spinozin, ili njegov fiziološki prihvatljiv N-demetilirani derivat ili njegova sol, namijenjen upotrebi u skladu s bilo kojim patentnim zahtjevom od 1 do 4, naznačen time što navedeni spinozin se primjenjuje oralno.
7. Spinozin, ili njegov fiziološki prihvatljiv N-demetilirani derivat ili njegova sol, namijenjen upotrebi u skladu s bilo kojim patentnim zahtjevom od 1 do 4, naznačen time što navedeni spinozin se primjenjuje parenteralno.
8. Spinozin, ili njegov fiziološki prihvatljiv N-demetilirani derivat ili njegova sol, namijenjen upotrebi u skladu s bilo kojim patentnim zahtjevom od 1 do 7, naznačen time što navedeni sisavac je ovca.
9. Spinozin, ili njegov fiziološki prihvatljiv N-demetilirani derivat ili njegova sol, namijenjen upotrebi u skladu s bilo kojim patentnim zahtjevom od 1 do 7, naznačen time što navedeni sisavac je čovjek.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2004/011268 WO2005112950A1 (en) | 2004-04-29 | 2004-04-29 | Spinosyns for wound healing |
| HR20100137 | 2010-03-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20100137T1 true HRP20100137T1 (hr) | 2010-04-30 |
Family
ID=34957480
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20100137T HRP20100137T1 (hr) | 2004-04-29 | 2010-03-10 | Spinozini, namijenjeni za zacjeljivanje rana |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US7709447B2 (hr) |
| EP (1) | EP1744763B1 (hr) |
| JP (1) | JP4880589B2 (hr) |
| CN (1) | CN1942194B (hr) |
| AT (1) | ATE454156T1 (hr) |
| AU (1) | AU2004319804B2 (hr) |
| BR (1) | BRPI0418764B8 (hr) |
| CA (1) | CA2563800C (hr) |
| CY (1) | CY1109840T1 (hr) |
| DE (1) | DE602004025050D1 (hr) |
| DK (1) | DK1744763T3 (hr) |
| EA (1) | EA010975B1 (hr) |
| ES (1) | ES2336573T3 (hr) |
| HK (1) | HK1099519A1 (hr) |
| HR (1) | HRP20100137T1 (hr) |
| IL (1) | IL178399A (hr) |
| MX (1) | MXPA06012388A (hr) |
| NO (1) | NO337210B1 (hr) |
| PL (1) | PL1744763T3 (hr) |
| PT (1) | PT1744763E (hr) |
| SI (1) | SI1744763T1 (hr) |
| WO (1) | WO2005112950A1 (hr) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0603252D0 (en) | 2006-02-17 | 2006-03-29 | Axcess Ltd | Dissolution aids for oral peptide delivery |
| EP2653160B1 (en) | 2006-10-12 | 2017-09-27 | Topaz Pharmaceuticals Inc. | Topical ivermectin formulations and methods for elimination and prophylaxis of body lice |
| US8697661B2 (en) | 2009-06-24 | 2014-04-15 | Christine Kritikou | Use of spinosyns and spinosyn compositions against herpesviridae viral infections |
| US9474729B2 (en) * | 2010-01-14 | 2016-10-25 | Hydromer, Inc. | Topical antimicrobial compositions and methods of using same |
| US9918991B2 (en) * | 2010-01-14 | 2018-03-20 | Hydromer, Inc. | Topical antimicrobial compositions and methods of using same |
| EP2528587B1 (en) | 2010-01-25 | 2015-03-18 | Eli Lilly and Company | Spinosyns for use in internally controlling or treating equine bot larvae |
| US10279007B2 (en) | 2010-11-15 | 2019-05-07 | Oxygenetix Institute, Inc. | Topical treatment method for healing wounds, disinfecting, covering and concealing the wound until healing occurs |
| WO2012085683A1 (en) * | 2010-12-22 | 2012-06-28 | Entarco Sa | The use of spinosyns and spinosyn compositions as local anesthetics and as antiarrhythmic agents |
| WO2017040769A1 (en) | 2015-09-03 | 2017-03-09 | Agrimetis, Llc | Spinosyn derivatives as insecticides |
| KR20190103341A (ko) | 2017-01-13 | 2019-09-04 | 에그리메티스, 엘엘씨 | 아지리딘 스피노신 유도체 및 제조 방법 |
| CN112770742A (zh) | 2018-07-27 | 2021-05-07 | 阿佩塔生物科学有限公司 | 用于治疗蠕形螨引起的眼部和面部疾病的多杀菌素制剂 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT1207756E (pt) | 1999-08-12 | 2006-07-31 | Lilly Co Eli | Utilizacao de espinosade ou de uma formulacao que compreende espinosade |
| WO2001011961A1 (en) * | 1999-08-12 | 2001-02-22 | Eli Lilly And Company | Control of ectoparasites using spinosyns |
| US6727228B2 (en) * | 2001-04-25 | 2004-04-27 | Johnson & Johnson Consumer Companies, Inc. | Pediculicidal and ovacidal treatment compositions and methods for killing head lice and their eggs |
| US20030026848A1 (en) * | 2001-07-06 | 2003-02-06 | Joshi Ashok V. | Beneficial materials for topical or internal use by a human or other animal |
| DK1435786T3 (da) * | 2001-09-17 | 2011-10-03 | Lilly Co Eli | Pesticide formuleringer |
-
2004
- 2004-04-29 CA CA2563800A patent/CA2563800C/en not_active Expired - Lifetime
- 2004-04-29 SI SI200431380T patent/SI1744763T1/sl unknown
- 2004-04-29 DK DK04822004.0T patent/DK1744763T3/da active
- 2004-04-29 AT AT04822004T patent/ATE454156T1/de active
- 2004-04-29 AU AU2004319804A patent/AU2004319804B2/en not_active Expired
- 2004-04-29 JP JP2007510666A patent/JP4880589B2/ja not_active Expired - Lifetime
- 2004-04-29 EA EA200602002A patent/EA010975B1/ru not_active IP Right Cessation
- 2004-04-29 CN CN2004800428998A patent/CN1942194B/zh not_active Expired - Lifetime
- 2004-04-29 MX MXPA06012388A patent/MXPA06012388A/es active IP Right Grant
- 2004-04-29 US US11/568,130 patent/US7709447B2/en active Active
- 2004-04-29 DE DE602004025050T patent/DE602004025050D1/de not_active Expired - Lifetime
- 2004-04-29 BR BRPI0418764A patent/BRPI0418764B8/pt active IP Right Grant
- 2004-04-29 PL PL04822004T patent/PL1744763T3/pl unknown
- 2004-04-29 ES ES04822004T patent/ES2336573T3/es not_active Expired - Lifetime
- 2004-04-29 PT PT04822004T patent/PT1744763E/pt unknown
- 2004-04-29 EP EP04822004A patent/EP1744763B1/en not_active Expired - Lifetime
- 2004-04-29 WO PCT/US2004/011268 patent/WO2005112950A1/en active Application Filing
-
2006
- 2006-09-28 IL IL178399A patent/IL178399A/en active IP Right Grant
- 2006-11-27 NO NO20065447A patent/NO337210B1/no unknown
-
2007
- 2007-06-22 HK HK07106700.1A patent/HK1099519A1/xx not_active IP Right Cessation
-
2010
- 2010-02-25 CY CY20101100184T patent/CY1109840T1/el unknown
- 2010-03-10 HR HR20100137T patent/HRP20100137T1/hr unknown
- 2010-03-16 US US12/724,499 patent/US8536142B2/en not_active Expired - Lifetime
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