HRP20080019T3 - Novi 3,3-dimetil-5-cijanobenzoksepinski derivati,korisni za dobivanje 5-formilbenzoksepinskih derivata - Google Patents
Novi 3,3-dimetil-5-cijanobenzoksepinski derivati,korisni za dobivanje 5-formilbenzoksepinskih derivataInfo
- Publication number
- HRP20080019T3 HRP20080019T3 HR20080019T HRP20080019T HRP20080019T3 HR P20080019 T3 HRP20080019 T3 HR P20080019T3 HR 20080019 T HR20080019 T HR 20080019T HR P20080019 T HRP20080019 T HR P20080019T HR P20080019 T3 HRP20080019 T3 HR P20080019T3
- Authority
- HR
- Croatia
- Prior art keywords
- optionally halogenated
- alkyl
- aryl
- groups
- optionally
- Prior art date
Links
- KUYFUQGIVNWVLX-UHFFFAOYSA-N 1-benzoxepine-5-carbaldehyde Chemical class O=CC1=CC=COC2=CC=CC=C12 KUYFUQGIVNWVLX-UHFFFAOYSA-N 0.000 title 1
- FTDPTXRLWPNVQB-UHFFFAOYSA-N 3,3-dimethyl-2h-1-benzoxepine-5-carbonitrile Chemical class N#CC1=CC(C)(C)COC2=CC=CC=C21 FTDPTXRLWPNVQB-UHFFFAOYSA-N 0.000 title 1
- 125000000041 C6-C10 aryl group Chemical group 0.000 abstract 4
- 125000003545 alkoxy group Chemical group 0.000 abstract 4
- 125000005843 halogen group Chemical group 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 125000006702 (C1-C18) alkyl group Chemical group 0.000 abstract 2
- 125000006527 (C1-C5) alkyl group Chemical group 0.000 abstract 2
- 125000006652 (C3-C12) cycloalkyl group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000000392 cycloalkenyl group Chemical group 0.000 abstract 2
- LWZYUACNWRVDDJ-UHFFFAOYSA-N 1-benzoxepine Chemical group O1C=CC=CC2=CC=CC=C12 LWZYUACNWRVDDJ-UHFFFAOYSA-N 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000005129 aryl carbonyl group Chemical group 0.000 abstract 1
- 125000005161 aryl oxy carbonyl group Chemical group 0.000 abstract 1
- 125000004104 aryloxy group Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000004465 cycloalkenyloxy group Chemical group 0.000 abstract 1
- 125000000000 cycloalkoxy group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
- C07D313/02—Seven-membered rings
- C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D313/08—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with one six-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrane Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Spojevi opće formule (I): gdjesvakog od R se neovisno bira između atoma halogena; skupine cijano; skupine nitro; skupine karboksi; izborno halogenirane (C1-C18)alkoksikarbonilne skupine; skupine Ra-CO-NH- ili RaRbN-CO- [gdje Ra i Rb neovisno predstavljaju izborno halogenirani (C1-C18)alkil; atom vodika; (C6-C10)aril ili (C6-C10)aril(C1-C5)alkil (gdje su arilni djelovi izborno supstituirani s atomom halogena, s izborno halogeniranom (C1-C5)alkilnom skupinom ili s izborno halogeniranom (C1-C5)alkoksi skupinom); (C3-C12)cikloalkil izborno supstituiran s atomom halogena, s izborno halogeniranom (C1-C5)alkilnom skupinom ili s izborno halogeniranom (C1-C5)alkoksi skupinom]; izborno halogenirane (C1-C18)alkilne skupine; izborno halogeniranog (C1-C18)alkoksi; i (C6-C10)arila, (C6-C10)aril(C1-C5) alkila, (C6-C10)ariloksi, (C3-C12)cikloalkila, (C3-C12)cikloalkenila, (C3-C12)cikloalkiloksi, (C3-C12)cikloalkeniloksi; (C6-C10)ariloksikarbonila ili (C6-C10)arilkarbonila; gdje su arilni, cikloalkilni i cikloalkenilni djelovi izborno supstituirani satomom halogena, s izborno halogeniranim (C1-C5)alkilom ili s izborno halogeniranim (C1-C5)alkoksi;R se može nalaziti na položaju 6, 7, 8 ili 9 u benzoksepinskoj strukturi; p predstavlja 0, 1, 2, 3 ili 4; kao i kao njihov geometrijski izomeri i stereoizomeri spojeva formule (I) ili njihove smjese.Patent sadrži još 24 patentna zahtjeva.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04291268A EP1600446B1 (en) | 2004-05-18 | 2004-05-18 | New 3,3-dimethyl-5-cyano-benzoxepine derivatives useful for the preparation of 5-formyl-benzoxepine derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20080019T3 true HRP20080019T3 (hr) | 2008-02-29 |
Family
ID=34931107
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20080019T HRP20080019T3 (hr) | 2004-05-18 | 2008-01-15 | Novi 3,3-dimetil-5-cijanobenzoksepinski derivati,korisni za dobivanje 5-formilbenzoksepinskih derivata |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP1600446B1 (hr) |
| AR (1) | AR049105A1 (hr) |
| AT (1) | ATE375988T1 (hr) |
| CY (1) | CY1107144T1 (hr) |
| DE (1) | DE602004009544T2 (hr) |
| DK (1) | DK1600446T3 (hr) |
| ES (1) | ES2297350T3 (hr) |
| HR (1) | HRP20080019T3 (hr) |
| PL (1) | PL1600446T3 (hr) |
| PT (1) | PT1600446E (hr) |
| SI (1) | SI1600446T1 (hr) |
| WO (1) | WO2005111012A1 (hr) |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2787789B1 (fr) * | 1998-12-29 | 2002-06-14 | Lipha | Benzopyranes et benzoxepines utilisables dans le traitement de dyslipidemies, de l'atherosclerose et du diabete, compositions pharmaceutiques les contenant et procedes de preparations |
-
2004
- 2004-05-18 AT AT04291268T patent/ATE375988T1/de active
- 2004-05-18 PT PT04291268T patent/PT1600446E/pt unknown
- 2004-05-18 ES ES04291268T patent/ES2297350T3/es not_active Expired - Lifetime
- 2004-05-18 DK DK04291268T patent/DK1600446T3/da active
- 2004-05-18 SI SI200430567T patent/SI1600446T1/sl unknown
- 2004-05-18 PL PL04291268T patent/PL1600446T3/pl unknown
- 2004-05-18 EP EP04291268A patent/EP1600446B1/en not_active Expired - Lifetime
- 2004-05-18 DE DE602004009544T patent/DE602004009544T2/de not_active Expired - Lifetime
-
2005
- 2005-04-27 WO PCT/EP2005/004472 patent/WO2005111012A1/en active Application Filing
- 2005-05-18 AR ARP050102036A patent/AR049105A1/es unknown
-
2008
- 2008-01-15 HR HR20080019T patent/HRP20080019T3/hr unknown
- 2008-01-17 CY CY20081100065T patent/CY1107144T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CY1107144T1 (el) | 2012-10-24 |
| WO2005111012A1 (en) | 2005-11-24 |
| PT1600446E (pt) | 2008-01-23 |
| EP1600446B1 (en) | 2007-10-17 |
| ES2297350T3 (es) | 2008-05-01 |
| EP1600446A1 (en) | 2005-11-30 |
| SI1600446T1 (sl) | 2008-04-30 |
| DE602004009544D1 (de) | 2007-11-29 |
| DK1600446T3 (da) | 2008-03-03 |
| PL1600446T3 (pl) | 2008-03-31 |
| ATE375988T1 (de) | 2007-11-15 |
| DE602004009544T2 (de) | 2008-08-07 |
| AR049105A1 (es) | 2006-06-28 |
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