HRP20040673A2 - Crystalline solids of carvedilol and processes for their preparation - Google Patents

Crystalline solids of carvedilol and processes for their preparation

Info

Publication number
HRP20040673A2
HRP20040673A2 HR20040673A HRP20040673A HRP20040673A2 HR P20040673 A2 HRP20040673 A2 HR P20040673A2 HR 20040673 A HR20040673 A HR 20040673A HR P20040673 A HRP20040673 A HR P20040673A HR P20040673 A2 HRP20040673 A2 HR P20040673A2
Authority
HR
Croatia
Prior art keywords
carvedilol
processes
preparation
crystalline solids
solids
Prior art date
Application number
HR20040673A
Other languages
English (en)
Inventor
Kor Ilan
Wizel Shlomit
Original Assignee
Teva Pharmaceutical Industries Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23371828&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP20040673(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Teva Pharmaceutical Industries Ltd. filed Critical Teva Pharmaceutical Industries Ltd.
Publication of HRP20040673A2 publication Critical patent/HRP20040673A2/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Medicinal Preparation (AREA)
HR20040673A 2002-01-15 2004-07-21 Crystalline solids of carvedilol and processes for their preparation HRP20040673A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US34931002P 2002-01-15 2002-01-15
PCT/US2003/001137 WO2003059807A2 (fr) 2002-01-15 2003-01-15 Corps solides cristallins de carvedilol, et leurs procedes d'elaboration

Publications (1)

Publication Number Publication Date
HRP20040673A2 true HRP20040673A2 (en) 2005-06-30

Family

ID=23371828

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20040673A HRP20040673A2 (en) 2002-01-15 2004-07-21 Crystalline solids of carvedilol and processes for their preparation

Country Status (14)

Country Link
US (3) US6710184B2 (fr)
EP (1) EP1474133A4 (fr)
JP (1) JP2005515226A (fr)
KR (1) KR20040077872A (fr)
CN (1) CN1298322C (fr)
AU (1) AU2003205146A1 (fr)
CA (1) CA2472377A1 (fr)
HR (1) HRP20040673A2 (fr)
IS (1) IS7351A (fr)
MX (1) MXPA04006909A (fr)
NO (1) NO20043383L (fr)
PL (1) PL371409A1 (fr)
WO (1) WO2003059807A2 (fr)
ZA (1) ZA200405443B (fr)

Families Citing this family (30)

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US6389455B1 (en) * 1998-09-22 2002-05-14 Richard C. Fuisz Method and apparatus for bouncing electronic messages
US20010036959A1 (en) * 2000-04-03 2001-11-01 Gabel Rolf Dieter Carvedilol-hydrophilic solutions
CN1245974C (zh) 2000-06-28 2006-03-22 特瓦制药工业有限公司 卡维地洛
US7049146B2 (en) 2000-11-14 2006-05-23 Facet Analytical Services And Technology, Llc Calibration standards, methods, and kits for water determination
US7122376B2 (en) * 2001-11-01 2006-10-17 Facet Analytical Services And Technology, Llc Calibration standards, methods, and kits for water determination
US8101209B2 (en) 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
CA2472377A1 (fr) 2002-01-15 2003-07-24 Teva Pharmaceutical Industries Ltd. Corps solides cristallins de carvedilol, et leurs procedes d'elaboration
WO2003092622A2 (fr) * 2002-04-30 2003-11-13 Sb Pharmco Puerto Rico Inc. Monocitrate monohydrate de carvedilol
EP1539140A4 (fr) * 2002-06-27 2005-12-07 Sb Pharmco Inc Hydobromure de carvedilol
CN103288714A (zh) * 2002-06-27 2013-09-11 史密斯克莱.比奇曼（科克）有限公司 卡维地洛磷酸盐和/或其溶剂合物相应的组合物和/或治疗方法
US20040152756A1 (en) * 2002-07-15 2004-08-05 Wei Chen Carvedilol polymorph
EP1615888A1 (fr) * 2003-04-21 2006-01-18 Matrix Laboratories Ltd Procede de fabrication de carvedilol, forme-ii
US20050036953A1 (en) * 2003-08-13 2005-02-17 Moshe Arkin Topical compositions of ammonium lactate
US20050042182A1 (en) * 2003-08-13 2005-02-24 Moshe Arkin Topical compositions of urea
US20050037040A1 (en) * 2003-08-13 2005-02-17 Moshe Arkin Topical compositions of urea and ammonium lactate
US20050042268A1 (en) * 2003-07-16 2005-02-24 Chaim Aschkenasy Pharmaceutical composition and method for transdermal drug delivery
SI21616A (sl) * 2003-09-02 2005-04-30 Krka, Tovarna Zdravil, D.D., Novo Mesto Nove kristalne oblike karvedilola
US20050069499A1 (en) * 2003-09-25 2005-03-31 Moshe Arkin Foamable compositions, processes of preparing same and uses thereof
WO2005051325A2 (fr) * 2003-11-25 2005-06-09 Sb Pharmco Puerto Rico Inc. Base libre de carvedilol, ses sels, formes anhydres ou solvats, compositions pharmaceutiques correspondantes, formulations a liberation controlee, et methodes de traitement ou d'administration
US7750036B2 (en) * 2003-11-25 2010-07-06 Sb Pharmco Puerto Rico Inc. Carvedilol salts, corresponding compositions, methods of delivery and/or treatment
US20060057075A1 (en) * 2004-08-02 2006-03-16 Moshe Arkin Pharmaceutical and cosmeceutical wash-off mousse shampoo compositions, processes for preparing the same and uses thereof
US20070043099A1 (en) * 2005-06-09 2007-02-22 Igor Lifshitz Crystalline forms of carvedilol and processes for their preparation
WO2007043938A1 (fr) * 2005-10-07 2007-04-19 Astrazeneca Ab Nouvelle forme cristalline de 3,5-dibromo-n-[(2s)-2-(4-fluorophenyl)-4-(3-morpholin-4-ylazetidin-1-yl)butyl]-n-methylbenzamide, modification b
WO2007077111A1 (fr) * 2005-12-30 2007-07-12 F. Hoffmann-La Roche Ag Composés et méthodes pour la synthèse de carbazole
WO2008002683A2 (fr) 2006-06-28 2008-01-03 Teva Pharmaceutical Industries Ltd. Carvédilol phosphate
GB2442238B (en) * 2006-09-29 2008-10-01 Rolls Royce Plc Sheet metal blank
US20080249317A1 (en) * 2007-04-04 2008-10-09 Apotex Inc. Novel amorphous form of carvedilol phosphate and processes for the preparation thereof
JP5517946B2 (ja) * 2007-11-14 2014-06-11 ジデケル，マヌエル 抗新生物活性を有するナンキョクコメススキ（ＤｅｓｃｈａｍｐｓｉａａｎｔａｒｃｔｉｃａＤｅｓｖ．）の新規抽出物
WO2015031914A1 (fr) * 2013-08-30 2015-03-05 Uti Limited Partnership Inhibiteurs de libération du calcium induite par une surcharge du stock calcique et leurs méthodes de production et d'utilisation
TW201946625A (zh) 2013-11-15 2019-12-16 美商阿克比治療有限公司 {[5-(3-氯苯基)-3-羥基吡啶-2-羰基]胺基}乙酸之固體型式，其組合物及用途

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DE2815926A1 (de) * 1978-04-13 1979-10-18 Boehringer Mannheim Gmbh Neue carbazolyl-(4)-oxy-propanolamin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3319027A1 (de) * 1983-05-26 1984-11-29 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur herstellung von optisch aktiven carbazol-derivaten, neue r- und s-carbazol-derivate, sowie arzneimittel, die diese verbindungen enthalten
FR2725623A1 (fr) 1994-10-18 1996-04-19 Flamel Tech Sa Microcapsules medicamenteuses et/ou nutritionnelles pour administration per os
US5760069A (en) 1995-02-08 1998-06-02 Boehringer Mannheim Pharmaceuticals Corporation-Smithkline Beecham Corporation Limited Partnership #1 Method of treatment for decreasing mortality resulting from congestive heart failure
EP0893440A1 (fr) * 1997-07-22 1999-01-27 Roche Diagnostics GmbH Une modification thermodynamique stabilisée de 1-(4-carbazolyloxy)-3[2-(2-methoxyphenoxy)ethylamino]- 2-propanole, un procédé pour sa préparation et une composition pharmaceutique qui la contient
US6730326B2 (en) 1997-07-22 2004-05-04 Roche Diagnostics Gmbh Thermodynamically stable modification of 1-(4-carbazolyl-oxy-3[2-(2-methoxyphenoxy)-ethylamino]-2-propanol process for its preparation and pharmaceutical compositions containing it
HU227441B1 (en) * 1997-11-24 2011-06-28 Egis Gyogyszergyar Nyilvanosan Muekoedoe Reszvenytarsasag Process for producing carvedilol, enantiomers and salts thereof
DE19954569A1 (de) 1999-11-12 2001-05-17 Schwabe Willmar Gmbh & Co Pharmakologisch aktive Tetrahydrothiopyran-4-ol-Derivate, Verfahren zu ihrer Herstellung und Verwendung
CN1245974C (zh) * 2000-06-28 2006-03-22 特瓦制药工业有限公司 卡维地洛
CA2434408C (fr) 2001-01-25 2009-10-20 F. Hoffmann-La Roche Ag Procede de preparation d'analogues d'indene heterocycliques
ATE328595T1 (de) * 2001-07-13 2006-06-15 Smithkline Beecham Corp Carvedilolpolymorph
BR0212927A (pt) 2001-09-28 2004-10-13 Hoffmann La Roche Formas pseudopolimórficas de carvedilol
CA2472377A1 (fr) 2002-01-15 2003-07-24 Teva Pharmaceutical Industries Ltd. Corps solides cristallins de carvedilol, et leurs procedes d'elaboration
CN103288714A (zh) 2002-06-27 2013-09-11 史密斯克莱.比奇曼（科克）有限公司 卡维地洛磷酸盐和/或其溶剂合物相应的组合物和/或治疗方法
US20040152756A1 (en) * 2002-07-15 2004-08-05 Wei Chen Carvedilol polymorph
SK285547B6 (sk) 2002-11-08 2007-03-01 Zentiva, A. S. Spôsob prípravy Carvedilolu
EP1615888A1 (fr) 2003-04-21 2006-01-18 Matrix Laboratories Ltd Procede de fabrication de carvedilol, forme-ii
US7482471B2 (en) 2003-06-20 2009-01-27 Sun Pharmaceutical Industries Limited Process for preparation of 1-[9H-carbazol-4-yloxy]-3-[{2-(2-(-methoxy)phenoxy)-ethyl}-amino]-propan-2-ol
SI21616A (sl) 2003-09-02 2005-04-30 Krka, Tovarna Zdravil, D.D., Novo Mesto Nove kristalne oblike karvedilola
US7750036B2 (en) 2003-11-25 2010-07-06 Sb Pharmco Puerto Rico Inc. Carvedilol salts, corresponding compositions, methods of delivery and/or treatment
CA2560353A1 (fr) 2004-02-23 2005-09-01 Cadila Healthcare Limited Procede de preparation de carvedilol racemique
WO2005115981A2 (fr) 2004-04-22 2005-12-08 Usv Limited Nouveau procede de preparation de 1-(9h-carbazol-4-yloxy)-3-[[2-(-methoxyphenoxy)-ethyl] amino]-propan-2-ol
GB0411273D0 (en) 2004-05-20 2004-06-23 Cipla Ltd Process and product
ATE445601T1 (de) 2004-12-09 2009-10-15 Zach System Spa Verfahren zur herstellung von carvedilol und seinen enantiomeren
US20070027202A1 (en) 2005-06-07 2007-02-01 Ashok Kumar Process for the preparation of carvedilol and its salts
DE602006013688D1 (de) 2005-11-16 2010-05-27 Hoffmann La Roche Neues verfahren zur herstellung von thoc
WO2007077111A1 (fr) 2005-12-30 2007-07-12 F. Hoffmann-La Roche Ag Composés et méthodes pour la synthèse de carbazole
KR100746455B1 (ko) 2006-02-23 2007-08-03 안국약품 주식회사 고광학순도의 키랄 카베딜롤의 제조방법

Also Published As

Publication number Publication date
US7514467B2 (en) 2009-04-07
MXPA04006909A (es) 2005-04-19
CA2472377A1 (fr) 2003-07-24
JP2005515226A (ja) 2005-05-26
US20040171665A1 (en) 2004-09-02
AU2003205146A1 (en) 2003-07-30
IS7351A (is) 2004-07-13
WO2003059807A2 (fr) 2003-07-24
CN1298322C (zh) 2007-02-07
PL371409A1 (en) 2005-06-13
EP1474133A2 (fr) 2004-11-10
US20030166702A1 (en) 2003-09-04
CN1615133A (zh) 2005-05-11
US7598396B2 (en) 2009-10-06
WO2003059807A3 (fr) 2003-12-04
ZA200405443B (en) 2005-07-08
US6710184B2 (en) 2004-03-23
KR20040077872A (ko) 2004-09-07
EP1474133A4 (fr) 2006-02-01
US20090163721A1 (en) 2009-06-25
NO20043383L (no) 2004-08-13

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