HK1257799A1 - 6-取代的吡啶並[2，3-d]嘧啶類化合物作為蛋白激酶抑制劑 - Google Patents

6-取代的吡啶並[2，3-d]嘧啶類化合物作為蛋白激酶抑制劑

Info

Publication number
HK1257799A1
HK1257799A1 HK18111361.8A HK18111361A HK1257799A1 HK 1257799 A1 HK1257799 A1 HK 1257799A1 HK 18111361 A HK18111361 A HK 18111361A HK 1257799 A1 HK1257799 A1 HK 1257799A1
Authority
HK
Hong Kong
Prior art keywords
pyrimidines
protein kinase
kinase inhibitors
substituted pyrido
pyrido
Prior art date
Application number
HK18111361.8A
Other languages
English (en)
Inventor
徐亮
蔣昌盛
何皓
程航
Original Assignee
晟科藥業（江蘇）有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 晟科藥業（江蘇）有限公司 filed Critical 晟科藥業（江蘇）有限公司
Publication of HK1257799A1 publication Critical patent/HK1257799A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK18111361.8A 2017-01-24 2018-09-05 6-取代的吡啶並[2，3-d]嘧啶類化合物作為蛋白激酶抑制劑 HK1257799A1 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201710059652 2017-01-24

Publications (1)

Publication Number Publication Date
HK1257799A1 true HK1257799A1 (zh) 2019-11-01

Family

ID=62590224

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18111361.8A HK1257799A1 (zh) 2017-01-24 2018-09-05 6-取代的吡啶並[2，3-d]嘧啶類化合物作為蛋白激酶抑制劑

Country Status (2)

Country Link
CN (1) CN108191857B (zh)
HK (1) HK1257799A1 (zh)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109956940A (zh) * 2019-05-14 2019-07-02 上海贤鼎生物科技有限公司 一种帕博昔布中间体氰基化反应制备杂芳基氰化物的方法
CA3221997A1 (en) * 2021-06-09 2022-12-15 Jun Li Compound as cdk kinase inhibitor and use thereof
WO2023177356A2 (en) * 2022-03-18 2023-09-21 Engine Biosciences Pte. Ltd. Compounds and method for pkmyt1 inhibition
CN117430597A (zh) * 2022-07-14 2024-01-23 浙江同源康医药股份有限公司 用作cdk4激酶抑制剂的化合物及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002070662A2 (en) * 2001-03-02 2002-09-12 Gpc Biotech Ag Three hybrid assay system
GEP20063909B (en) * 2002-01-22 2006-08-25 Warner Lambert Co 2-(PYRIDIN-2-YLAMINO)-PYRIDO[2,3d] PYRIMIDIN-7-ONES
JP2007523151A (ja) * 2004-02-18 2007-08-16 ワーナー−ランバート カンパニー リミテッド ライアビリティー カンパニー ２−（ピリジン−３−イルアミノ）−ピリド［２，３−ｄ］ピリミジン−７−オン
AU2010303218A1 (en) * 2009-10-09 2012-05-10 Afraxis Holdings, Inc. 8-ethyl-6-(aryl)pyrido[2,3-d]pyrimidin-7(8H)-ones for the treatment of CNS disorders

Also Published As

Publication number Publication date
CN108191857A (zh) 2018-06-22
CN108191857B (zh) 2020-10-23

Similar Documents

Publication Publication Date Title
IL277576A (en) Mutated pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors
HK1258905A1 (zh) 作為ret激酶抑制劑的取代的吡唑並[1，5-a]吡啶化合物
IL265918A (en) Pyrazolo [1,5– A] compounds Pyridine is converted as RET kinase inhibitors
HK1255467A1 (zh) 作為雙重dyrk1/clk1抑制劑的新的吡咯並[2，3-d]嘧啶衍生物
PL3345907T3 (pl) Związki pirazolo[3,4-d]pirymidynowe lub ich sole
ZA201704494B (en) 4,6-substituted-pyrazolo[1,5-a]pyrazines as janus kinase inhibitors
PL3371185T3 (pl) Pochodne 4,5,6,7-tetrahydro-1h-imidazo[4,5-c]pirydyny i 1,4,5,6,7,8-heksahydroimidazo[4,5-d]azepiny jako inhibitory kinaz janusowych
PL3712152T3 (pl) Pochodne 4,5,6,7-tetrahydro-1h-imidazo[4,5-c]pirydyny i 1,4,5,6,7,8-heksahydroimidazo[4,5-d]azepiny jako inhibitory kinaz janusowych
HK1257799A1 (zh) 6-取代的吡啶並[2，3-d]嘧啶類化合物作為蛋白激酶抑制劑
IL262673A (en) Pyrazolo[1,5-a]pyrimidine compound
EP3630116A4 (en) TETRAHYDROPYRIDO [4,3-D] PYRIMIDINE KINASE ATR INHIBITORS
HK1251232A1 (zh) 吡咯並[2，3-d]嘧啶化合物或其鹽
PL3621966T3 (pl) Pochodne pirazolo[1,5-a]pirymidyny jako inhibitory kinazy JAK
HUE050298T2 (hu) Pirazolo[3,4-D]pirimidin vegyületek vagy annak sói