HK1257587A1 - 預防和治療肝纖維化的藥物及其用途 - Google Patents

預防和治療肝纖維化的藥物及其用途

Info

Publication number
HK1257587A1
HK1257587A1 HK18116706.1A HK18116706A HK1257587A1 HK 1257587 A1 HK1257587 A1 HK 1257587A1 HK 18116706 A HK18116706 A HK 18116706A HK 1257587 A1 HK1257587 A1 HK 1257587A1
Authority
HK
Hong Kong
Prior art keywords
medicine
preventing
liver fibrosis
treating liver
treating
Prior art date
Application number
HK18116706.1A
Other languages
English (en)
Inventor
李季男
Original Assignee
深圳瑞健生命科學研究院有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 深圳瑞健生命科學研究院有限公司 filed Critical 深圳瑞健生命科學研究院有限公司
Publication of HK1257587A1 publication Critical patent/HK1257587A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A61K38/484—Plasmin (3.4.21.7)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21007—Plasmin (3.4.21.7), i.e. fibrinolysin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK18116706.1A 2016-12-15 2018-12-28 預防和治療肝纖維化的藥物及其用途 HK1257587A1 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201611162270 2016-12-15

Publications (1)

Publication Number Publication Date
HK1257587A1 true HK1257587A1 (zh) 2019-10-25

Family

ID=62656674

Family Applications (5)

Application Number Title Priority Date Filing Date
HK18116704.3A HK1257585A1 (zh) 2016-12-15 2018-12-28 預防和治療皮膚纖維化的藥物及其用途
HK18116708.9A HK1257589A1 (zh) 2016-12-15 2018-12-28 預防和治療組織器官纖維化的藥物及其用途
HK18116707.0A HK1257588A1 (zh) 2016-12-15 2018-12-28 預防和治療肺纖維化的藥物及其用途
HK18116706.1A HK1257587A1 (zh) 2016-12-15 2018-12-28 預防和治療肝纖維化的藥物及其用途
HK18116703.4A HK1257584A1 (zh) 2016-12-15 2018-12-28 預防和治療系統性硬化症的藥物及其用途

Family Applications Before (3)

Application Number Title Priority Date Filing Date
HK18116704.3A HK1257585A1 (zh) 2016-12-15 2018-12-28 預防和治療皮膚纖維化的藥物及其用途
HK18116708.9A HK1257589A1 (zh) 2016-12-15 2018-12-28 預防和治療組織器官纖維化的藥物及其用途
HK18116707.0A HK1257588A1 (zh) 2016-12-15 2018-12-28 預防和治療肺纖維化的藥物及其用途

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK18116703.4A HK1257584A1 (zh) 2016-12-15 2018-12-28 預防和治療系統性硬化症的藥物及其用途

Country Status (2)

Country Link
CN (5) CN108210899A (zh)
HK (5) HK1257585A1 (zh)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110917335B (zh) * 2018-09-20 2023-06-27 华中科技大学同济医学院附属同济医院 Erdr1在预防和治疗纤维化疾病中的用途
WO2021155867A1 (zh) * 2020-02-06 2021-08-12 泰伦基国际有限公司 一种预防和治疗多发性硬化症的方法和药物
CA3169325A1 (en) * 2020-02-26 2021-09-02 Jinan Li Method and drug for preventing and treating abnormal blood pressure condition
CN113925022A (zh) * 2021-10-22 2022-01-14 莫汉有 一种系统性红斑狼疮并动脉粥样硬化动物模型构建方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA00011713A (es) * 2000-11-28 2002-05-31 Tgt Lab S A De C V Vectores recombinantes virales y no virales conteniendo el gen humano del activador de plasminogeno derivado de urocinasa y su utilidad en el tratamiento de diversos tipos de fibrosis hepatica, renal, pulmonar, pancreatica, cardiaca y cicatrices hipe
US7067492B2 (en) * 2001-09-06 2006-06-27 Omnio Ab Method of promoting healing of a tympanic membrane perforation
US20050250694A1 (en) * 2003-10-10 2005-11-10 Ma Jian-Xing Compounds useful in inhibiting vascular leakage, inflammation and fibrosis and methods of making and using same
NZ585715A (en) * 2007-11-29 2011-11-25 Talecris Biotherapeutics Inc Recombinantly modified plasmin
CA2767612A1 (en) * 2009-07-10 2011-01-13 Thrombogenics Nv Variants of plasminogen and plasmin
CN101628113B (zh) * 2009-08-18 2012-01-04 南京农业大学 蚯蚓纤溶酶抗肝纤维化的应用
EP2566514A4 (en) * 2010-05-03 2013-11-27 Abbvie Inc METHODS OF INHIBITING FIBROSIS WITH ANTI-PAI-1 ANTIBODIES
EP3593861B1 (en) * 2012-03-09 2022-12-14 Vascular Biosciences Combination of car peptide and a vasodilator for treating pulmonary hypertension
KR101467109B1 (ko) * 2013-07-10 2014-12-01 영남대학교 산학협력단 Ｂｉｘ02189 화합물을 유효성분으로 포함하는 폐섬유증 예방 또는 치료용 조성물
CN112142845A (zh) * 2013-08-13 2020-12-29 赛诺菲 纤溶酶原激活剂抑制剂-1(pai-1)的抗体及其用途
TW201722994A (zh) * 2013-08-13 2017-07-01 賽諾菲公司 胞漿素原活化素抑制劑-１（ｐａｉ-１）之抗體及其用途
US20160199466A1 (en) * 2013-08-20 2016-07-14 Trustees Of Dartmouth College Methods For Treating Tissue Fibrosis

Also Published As

Publication number Publication date
HK1257585A1 (zh) 2019-10-25
HK1257584A1 (zh) 2019-10-25
CN108210892A (zh) 2018-06-29
CN108210897A (zh) 2018-06-29
HK1257589A1 (zh) 2019-10-25
CN108210905A (zh) 2018-06-29
CN108210910A (zh) 2018-06-29
CN108210899A (zh) 2018-06-29
HK1257588A1 (zh) 2019-10-25

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