HK1251256A1 - 启動子變體 - Google Patents

启動子變體

Info

Publication number
HK1251256A1
HK1251256A1 HK18110716.2A HK18110716A HK1251256A1 HK 1251256 A1 HK1251256 A1 HK 1251256A1 HK 18110716 A HK18110716 A HK 18110716A HK 1251256 A1 HK1251256 A1 HK 1251256A1
Authority
HK
Hong Kong
Prior art keywords
promoter variants
promoter
variants
Prior art date
Application number
HK18110716.2A
Other languages
English (en)
Inventor
D‧馬塔諾維赫
B‧加塞爾
R‧普里爾霍弗
Original Assignee
龍沙有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 龍沙有限公司 filed Critical 龍沙有限公司
Publication of HK1251256A1 publication Critical patent/HK1251256A1/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • C12N1/16Yeasts; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00Vector systems having a special element relevant for transcription
    • C12N2830/001Vector systems having a special element relevant for transcription controllable enhancer/promoter combination

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Botany (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK18110716.2A 2015-08-05 2018-08-21 启動子變體 HK1251256A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP2015068024 2015-08-05
EP16163932 2016-04-05
PCT/EP2016/068784 WO2017021541A1 (en) 2015-08-05 2016-08-05 Promoter variants

Publications (1)

Publication Number Publication Date
HK1251256A1 true HK1251256A1 (zh) 2019-01-25

Family

ID=56684642

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18110716.2A HK1251256A1 (zh) 2015-08-05 2018-08-21 启動子變體

Country Status (14)

Country Link
US (2) US10752907B2 (zh)
EP (1) EP3332005B1 (zh)
JP (1) JP6833812B2 (zh)
KR (1) KR102253479B1 (zh)
CN (1) CN108350447B (zh)
AU (1) AU2016303026B2 (zh)
BR (1) BR112018002395A2 (zh)
CA (1) CA2992170C (zh)
DK (1) DK3332005T3 (zh)
ES (1) ES2902044T3 (zh)
HK (1) HK1251256A1 (zh)
IL (1) IL257000B (zh)
TW (1) TW201718859A (zh)
WO (1) WO2017021541A1 (zh)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3508494B1 (en) 2011-10-07 2022-02-23 Lonza Ltd Regulatable promoter
WO2019154686A1 (en) 2018-02-12 2019-08-15 Lonza Ltd Host cell for producing a protein of interest
EP3536784A1 (en) 2018-03-05 2019-09-11 ACIB GmbH Host cell engineered for improved metabolite production
EP3802832A1 (en) * 2018-06-07 2021-04-14 Basf Se Promoter for yeast
WO2020068019A2 (en) * 2018-09-24 2020-04-02 Orta Dogu Teknik Universitesi Design of alcohol dehydrogenase 2 (adh2) promoter variants by promoter engineering
JP2022502018A (ja) * 2018-09-24 2022-01-11 オルタ ドグ テクニク ユニヴェルシテシ 改変されたaox1プロモータバリアント
CN113423836B (zh) 2019-01-11 2023-07-11 龙沙有限公司 重组宿主细胞中碳源调节的蛋白的产生
PL3690052T3 (pl) * 2019-01-29 2023-08-14 Clariant Produkte (Deutschland) Gmbh Chimeryczny promotor do stosowania w inżynierii metabolicznej
WO2020200415A1 (en) 2019-04-01 2020-10-08 Lonza Ltd Mut- methylotrophic yeast
WO2020200414A1 (en) 2019-04-01 2020-10-08 Lonza Ltd Protein production in mut-methylotrophic yeast
EP3947695B1 (en) 2019-04-01 2023-09-06 Universität für Bodenkultur Wien Mut- methylotrophic yeast
WO2021198431A1 (en) 2020-04-01 2021-10-07 Lonza Ltd Helper factors for expressing proteins in yeast
US20230348545A1 (en) 2020-09-30 2023-11-02 Lonza Ltd Host cells overexpressing translational factors
WO2022171827A1 (en) 2021-02-12 2022-08-18 Boehringer Ingelheim Rcv Gmbh & Co Kg Signal peptides for increased protein secretion
CN114657190B (zh) * 2022-04-06 2023-08-29 暨南大学 Msn2p作为负调控因子在提高宿主细胞中蛋白表达中的应用
CN114908092B (zh) * 2022-05-12 2023-07-18 华南理工大学 一种长效、高强度的杂合启动子及其重组菌株和应用
EP4353825A1 (en) * 2022-10-10 2024-04-17 bisy GmbH Modified promoter sequences

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT501955B1 (de) 2005-02-23 2007-08-15 Univ Graz Tech Mutierte aox1-promotoren
US8105811B2 (en) * 2008-06-13 2012-01-31 Wisconsin Alumni Research Foundation Sugar transport sequences, yeast strains having improved sugar uptake, and methods of use
EP3508494B1 (en) * 2011-10-07 2022-02-23 Lonza Ltd Regulatable promoter
ES2789299T3 (es) 2012-10-29 2020-10-26 Lonza Ag Secuencias de expresión

Also Published As

Publication number Publication date
CN108350447B (zh) 2021-08-31
AU2016303026A1 (en) 2018-02-15
CN108350447A (zh) 2018-07-31
JP6833812B2 (ja) 2021-02-24
IL257000B (en) 2022-06-01
KR102253479B1 (ko) 2021-05-21
KR20180037237A (ko) 2018-04-11
US20200347391A1 (en) 2020-11-05
CA2992170A1 (en) 2017-02-09
WO2017021541A1 (en) 2017-02-09
BR112018002395A2 (pt) 2018-09-18
US10752907B2 (en) 2020-08-25
AU2016303026B2 (en) 2020-10-22
TW201718859A (zh) 2017-06-01
JP2018522565A (ja) 2018-08-16
ES2902044T3 (es) 2022-03-24
US20180223293A1 (en) 2018-08-09
CA2992170C (en) 2022-08-16
EP3332005B1 (en) 2021-09-22
EP3332005A1 (en) 2018-06-13
IL257000A (en) 2018-03-29
DK3332005T3 (da) 2022-01-03

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