HK1248753A1 - 用於類風濕性關節炎的生物標記物及其用途 - Google Patents

用於類風濕性關節炎的生物標記物及其用途

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Publication number
HK1248753A1
HK1248753A1 HK18108502.4A HK18108502A HK1248753A1 HK 1248753 A1 HK1248753 A1 HK 1248753A1 HK 18108502 A HK18108502 A HK 18108502A HK 1248753 A1 HK1248753 A1 HK 1248753A1
Authority
HK
Hong Kong
Prior art keywords
biomarkers
usage
rheumatoid arthritis
rheumatoid
arthritis
Prior art date
Application number
HK18108502.4A
Other languages
English (en)
Inventor
馮强
張東亞
賈慧珏
王東輝
王俊
Original Assignee
深圳華大基因研究院
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/CN2014/088069 external-priority patent/WO2016049937A1/en
Priority claimed from PCT/CN2014/088068 external-priority patent/WO2016049936A1/en
Priority claimed from PCT/CN2014/088060 external-priority patent/WO2016049930A1/en
Application filed by 深圳華大基因研究院 filed Critical 深圳華大基因研究院
Publication of HK1248753A1 publication Critical patent/HK1248753A1/zh

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747Lactobacilli, e.g. L. acidophilus or L. brevis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/335Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Lactobacillus (G)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/106Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/118Prognosis of disease development
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers
HK18108502.4A 2014-09-30 2018-07-03 用於類風濕性關節炎的生物標記物及其用途 HK1248753A1 (zh)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
PCT/CN2014/088069 WO2016049937A1 (en) 2014-09-30 2014-09-30 Biomarkers for rheumatoid arthritis and usage therof
PCT/CN2014/088068 WO2016049936A1 (en) 2014-09-30 2014-09-30 Biomarkers for rheumatoid arthritis and usage therof
PCT/CN2014/088060 WO2016049930A1 (en) 2014-09-30 2014-09-30 Biomarkers for rheumatoid arthritis and usage therof
PCT/CN2015/083488 WO2016050110A1 (en) 2014-09-30 2015-07-07 Biomarkers for rheumatoid arthritis and usage thereof

Publications (1)

Publication Number Publication Date
HK1248753A1 true HK1248753A1 (zh) 2018-10-19

Family

ID=55629412

Family Applications (2)

Application Number Title Priority Date Filing Date
HK18108512.2A HK1248764A1 (zh) 2014-09-30 2018-07-03 用於類風濕性關節炎的生物標記物及其用途
HK18108502.4A HK1248753A1 (zh) 2014-09-30 2018-07-03 用於類風濕性關節炎的生物標記物及其用途

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK18108512.2A HK1248764A1 (zh) 2014-09-30 2018-07-03 用於類風濕性關節炎的生物標記物及其用途

Country Status (11)

Country Link
US (1) US10883146B2 (zh)
EP (1) EP3201317B1 (zh)
JP (1) JP6485843B2 (zh)
KR (1) KR101986442B1 (zh)
CN (2) CN108064272B (zh)
AU (1) AU2015327511B2 (zh)
CA (1) CA2963013C (zh)
DK (1) DK3201317T3 (zh)
HK (2) HK1248764A1 (zh)
RU (1) RU2691375C2 (zh)
WO (2) WO2016050111A1 (zh)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11514289B1 (en) * 2016-03-09 2022-11-29 Freenome Holdings, Inc. Generating machine learning models using genetic data
WO2019071516A1 (en) * 2017-10-12 2019-04-18 Perfect (China) Co., Ltd. BIOMARKERS FOR CHRONIC HEPATITIS B AND THEIR USE
CN108034708B (zh) * 2017-12-14 2020-05-22 中国中医科学院中药研究所 通过多个mRNA的表达量确定雷公藤多苷片治疗类风湿性关节炎的个体有效性的系统
CN109065168B (zh) * 2018-08-29 2021-09-14 昆明理工大学 一种基于时空聚类统计进行疾病风险评估的方法
CN111161794B (zh) * 2018-12-30 2024-03-22 深圳碳云智能数字生命健康管理有限公司 肠道微生物测序数据处理方法、装置、存储介质及处理器
CN111161795A (zh) * 2019-01-15 2020-05-15 深圳碳云智能数字生命健康管理有限公司 肠道微生物测序数据处理方法、装置、存储介质及处理器
JP2021010343A (ja) * 2019-07-08 2021-02-04 三菱ケミカル株式会社 口腔内細菌による健康状態の予測方法
CN113488107B (zh) * 2021-07-07 2022-07-19 广州华银康医疗集团股份有限公司 筛选免疫组库测序生物标志物的方法、设备和存储介质
CN114369671A (zh) * 2021-11-25 2022-04-19 上海锐翌生物科技有限公司 风湿性关节炎标志微生物及其应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20030274A1 (es) * 2001-07-26 2003-05-08 Alimentary Health Ltd Cepas de lactobacillus salivarius
RU2362808C1 (ru) * 2008-02-13 2009-07-27 Государственное образовательное учреждение дополнительного профессионального образования Российская медицинская академия последипломного образования Федерального агентства по здравоохранению и социальному развитию (ГОУ ДПО РМАПО Росздрава) Способ диагностики дисбаланса микробиоты различных биотопов человека и степени его выраженности
CN101886132B (zh) * 2009-07-15 2013-09-18 北京百迈客生物科技有限公司 基于测序和bsa技术的性状相关的分子标记筛选方法
CN101921748B (zh) * 2010-06-30 2012-11-14 上海华大基因科技有限公司 用于高通量检测人类乳头瘤病毒的dna分子标签
CN105063186A (zh) * 2011-11-10 2015-11-18 霍夫曼-拉罗奇有限公司 用于治疗、诊断和监测阿尔茨海默病的方法
JP5863035B2 (ja) 2012-03-07 2016-02-16 国立大学法人 東京大学 炎症性腸疾患の検出方法及びヒト唾液細菌叢の検査方法
WO2014019180A1 (zh) * 2012-08-01 2014-02-06 深圳华大基因研究院 确定异常状态生物标记物的方法及系统
WO2014019271A1 (en) * 2012-08-01 2014-02-06 Bgi Shenzhen Biomarkers for diabetes and usages thereof

Also Published As

Publication number Publication date
AU2015327511A1 (en) 2017-04-20
WO2016050111A1 (en) 2016-04-07
CN108064263B (zh) 2022-04-26
RU2017115001A3 (zh) 2018-11-05
WO2016050110A1 (en) 2016-04-07
RU2691375C2 (ru) 2019-06-11
DK3201317T3 (da) 2020-01-20
KR20170063879A (ko) 2017-06-08
RU2017115001A (ru) 2018-11-05
CN108064263A (zh) 2018-05-22
US10883146B2 (en) 2021-01-05
EP3201317B1 (en) 2019-12-11
HK1248764A1 (zh) 2018-10-19
US20170226565A1 (en) 2017-08-10
EP3201317A1 (en) 2017-08-09
KR101986442B1 (ko) 2019-06-05
CA2963013A1 (en) 2016-04-07
AU2015327511B2 (en) 2018-12-06
CN108064272B (zh) 2021-07-09
CA2963013C (en) 2022-10-04
CN108064272A (zh) 2018-05-22
JP2017530708A (ja) 2017-10-19
EP3201317A4 (en) 2017-08-09
JP6485843B2 (ja) 2019-03-20

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