HK1248147A1 - 布魯頓氏酪氨酸激酶抑制劑的溶劑化形式 - Google Patents

布魯頓氏酪氨酸激酶抑制劑的溶劑化形式

Info

Publication number
HK1248147A1
HK1248147A1 HK18107889.9A HK18107889A HK1248147A1 HK 1248147 A1 HK1248147 A1 HK 1248147A1 HK 18107889 A HK18107889 A HK 18107889A HK 1248147 A1 HK1248147 A1 HK 1248147A1
Authority
HK
Hong Kong
Prior art keywords
bruton
tyrosine kinase
kinase inhibitor
solvated forms
solvated
Prior art date
Application number
HK18107889.9A
Other languages
English (en)
Inventor
艾瑞克‧戈德曼
M‧S‧史密斯
蒂埃裏‧伯諾德
阿爾貝托‧穆諾茲加西亞
克裏斯多佛‧彼得‧沃洛
Original Assignee
藥品循環有限責任公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 藥品循環有限責任公司 filed Critical 藥品循環有限責任公司
Publication of HK1248147A1 publication Critical patent/HK1248147A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N23/00—Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups G01N3/00 – G01N17/00, G01N21/00 or G01N22/00
    • G01N23/20—Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups G01N3/00 – G01N17/00, G01N21/00 or G01N22/00 by using diffraction of the radiation by the materials, e.g. for investigating crystal structure; by using scattering of the radiation by the materials, e.g. for investigating non-crystalline materials; by using reflection of the radiation by the materials
    • G01N23/20075—Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups G01N3/00 – G01N17/00, G01N21/00 or G01N22/00 by using diffraction of the radiation by the materials, e.g. for investigating crystal structure; by using scattering of the radiation by the materials, e.g. for investigating non-crystalline materials; by using reflection of the radiation by the materials by measuring interferences of X-rays, e.g. Borrmann effect

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK18107889.9A 2015-03-27 2018-06-19 布魯頓氏酪氨酸激酶抑制劑的溶劑化形式 HK1248147A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562139594P 2015-03-27 2015-03-27
PCT/US2016/024305 WO2016160598A1 (en) 2015-03-27 2016-03-25 Solvated forms of a bruton's tyrosine kinase inhibitor

Publications (1)

Publication Number Publication Date
HK1248147A1 true HK1248147A1 (zh) 2018-10-12

Family

ID=57006292

Family Applications (2)

Application Number Title Priority Date Filing Date
HK18107889.9A HK1248147A1 (zh) 2015-03-27 2018-06-19 布魯頓氏酪氨酸激酶抑制劑的溶劑化形式
HK18109251.5A HK1249737A1 (zh) 2015-03-27 2018-07-17 布魯頓氏酪氨酸激酶抑制劑的溶劑化形式

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK18109251.5A HK1249737A1 (zh) 2015-03-27 2018-07-17 布魯頓氏酪氨酸激酶抑制劑的溶劑化形式

Country Status (11)

Country Link
US (4) US20180072738A1 (zh)
EP (1) EP3273961A4 (zh)
JP (2) JP2018509457A (zh)
CN (1) CN107530346A (zh)
AU (1) AU2016243116A1 (zh)
BR (1) BR112017020744A2 (zh)
CA (1) CA2981048A1 (zh)
HK (2) HK1248147A1 (zh)
MA (1) MA41827A (zh)
MX (1) MX2017012430A (zh)
WO (1) WO2016160598A1 (zh)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20230170108A (ko) 2012-06-04 2023-12-18 파마싸이클릭스 엘엘씨 브루톤 타이로신 키나아제 저해제의 결정 형태
PT3265084T (pt) 2015-03-03 2024-02-13 Pharmacyclics Llc Formulações farmacêuticas de inibidor de tirosina cinase de bruton
WO2017029586A1 (en) * 2015-08-19 2017-02-23 Sun Pharmaceutical Industries Limited Crystalline forms of ibrutinib
CZ2016276A3 (cs) * 2016-05-11 2017-11-22 Zentiva, K.S. Pevné formy volné báze ibrutinibu
US10183024B2 (en) 2016-12-02 2019-01-22 Apotex Inc. Crystalline forms of ibrutinib
CZ2017787A3 (cs) 2017-12-08 2019-06-19 Zentiva, K.S. Farmaceutické kompozice obsahující ibrutinib
EP3575300A1 (en) 2018-05-31 2019-12-04 Apotex Inc. Novel crystalline forms of ibrutinib
EP3669867A1 (en) 2018-12-21 2020-06-24 Synthon B.V. Pharmaceutical composition comprising ibrutinib
US10688050B1 (en) 2018-12-21 2020-06-23 Synthon B.V. Pharmaceutical composition comprising ibrutinib
WO2023242384A1 (en) 2022-06-17 2023-12-21 Krka, D.D., Novo Mesto Crystalline form of ibrutinib

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DE3303707A1 (de) * 1983-02-04 1984-08-09 Dynamit Nobel Ag, 5210 Troisdorf Verfahren zur spaltung von organosiloxanen und dessen produkte und anwendungen
US4624848A (en) 1984-05-10 1986-11-25 Ciba-Geigy Corporation Active agent containing hydrogel devices wherein the active agent concentration profile contains a sigmoidal concentration gradient for improved constant release, their manufacture and use
US4968509A (en) 1987-07-27 1990-11-06 Mcneilab, Inc. Oral sustained release acetaminophen formulation and process
IL92966A (en) 1989-01-12 1995-07-31 Pfizer Hydrogel-operated release devices
DK0580860T4 (da) 1991-04-16 2005-03-21 Nippon Shinyaku Co Ltd Fremgangsmåde til fremstilling af en fast dispersion
AU661080B2 (en) 1991-11-22 1995-07-13 Warner Chilcott Company, Llc Risedronate delayed-release compositions
US5461140A (en) 1992-04-30 1995-10-24 Pharmaceutical Delivery Systems Bioerodible polymers for solid controlled release pharmaceutical compositions
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US5686105A (en) 1993-10-19 1997-11-11 The Procter & Gamble Company Pharmaceutical dosage form with multiple enteric polymer coatings for colonic delivery
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JPH11505258A (ja) 1995-05-17 1999-05-18 セダーシナイ メディカル センター 小腸における消化および吸収を改善させる脂肪酸を含む組成物
CO5210907A1 (es) * 1999-05-12 2002-10-30 Novartis Ag Solvatos de pometrozina, insecticidamente activos, composiciones que contienen estos compuestos y metodos tanto para producir dichos compuestos y composiciones como para controlar plagas animales con estas composiciones
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EP2157524A3 (en) 2003-09-03 2010-12-08 GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Methods for identifying, diagnosing, and predicting survival of lymphomas
EP2530083B1 (en) 2006-09-22 2016-04-27 Pharmacyclics LLC Inhibitors of bruton's tyrosine kinase
SG10202107066WA (en) * 2007-03-28 2021-07-29 Pharmacyclics Llc Inhibitors of bruton's tyrosine kinase
US8541391B2 (en) * 2010-10-28 2013-09-24 Viropharma Incorporated Crystalline phases of 5,6-dichloro-2-(isopropylamino)-1-β-L-ribofuranosyl-1H-benzimidazole
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KR20230170108A (ko) * 2012-06-04 2023-12-18 파마싸이클릭스 엘엘씨 브루톤 타이로신 키나아제 저해제의 결정 형태
CA2908375A1 (en) * 2013-04-08 2014-10-16 Pharmacyclics Llc Ibrutinib combination therapy
CN103923084B (zh) * 2014-01-29 2016-08-17 苏州晶云药物科技有限公司 几种晶型及其制备方法

Also Published As

Publication number Publication date
HK1249737A1 (zh) 2018-11-09
MX2017012430A (es) 2018-07-06
JP2022033783A (ja) 2022-03-02
WO2016160598A1 (en) 2016-10-06
US20220106317A1 (en) 2022-04-07
US20200347063A1 (en) 2020-11-05
BR112017020744A2 (pt) 2018-07-17
JP2018509457A (ja) 2018-04-05
US20180072738A1 (en) 2018-03-15
US20190367519A1 (en) 2019-12-05
EP3273961A4 (en) 2018-10-31
EP3273961A1 (en) 2018-01-31
CA2981048A1 (en) 2016-10-06
AU2016243116A1 (en) 2017-10-19
CN107530346A (zh) 2018-01-02
MA41827A (fr) 2018-01-30

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