HK1243929A1 - Tlr抑制劑和布魯頓酪氨酸激酶抑制劑組合 - Google Patents
Tlr抑制劑和布魯頓酪氨酸激酶抑制劑組合Info
- Publication number
- HK1243929A1 HK1243929A1 HK18103426.8A HK18103426A HK1243929A1 HK 1243929 A1 HK1243929 A1 HK 1243929A1 HK 18103426 A HK18103426 A HK 18103426A HK 1243929 A1 HK1243929 A1 HK 1243929A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- inhibitor
- bruton
- tyrosine kinase
- combinations
- tlr
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4706—4-Aminoquinolines; 8-Aminoquinolines, e.g. chloroquine, primaquine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462080921P | 2014-11-17 | 2014-11-17 | |
US201562127740P | 2015-03-03 | 2015-03-03 | |
PCT/US2015/061091 WO2016081460A1 (en) | 2014-11-17 | 2015-11-17 | Tlr inhibitor and bruton's tyrosine kinase inhibitor combinations |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1243929A1 true HK1243929A1 (zh) | 2018-07-27 |
Family
ID=56014455
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK18103426.8A HK1243929A1 (zh) | 2014-11-17 | 2018-03-12 | Tlr抑制劑和布魯頓酪氨酸激酶抑制劑組合 |
Country Status (11)
Country | Link |
---|---|
US (1) | US20170354655A1 (zh) |
EP (1) | EP3220912A4 (zh) |
JP (1) | JP2017533944A (zh) |
CN (1) | CN106999495A (zh) |
AU (1) | AU2015350136A1 (zh) |
BR (1) | BR112017010262A2 (zh) |
CA (1) | CA2966542A1 (zh) |
HK (1) | HK1243929A1 (zh) |
MX (1) | MX2017006464A (zh) |
TW (1) | TW201628622A (zh) |
WO (1) | WO2016081460A1 (zh) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2006249866B2 (en) | 2005-05-26 | 2011-10-13 | Aldeyra Therapeutics, Inc. | Compositions and methods of treating retinal disease |
NZ772688A (en) | 2010-06-03 | 2022-09-30 | Pharmacyclics Llc | The use of inhibitors of bruton’s tyrosine kinase (btk) |
CA2879570A1 (en) | 2012-07-24 | 2014-01-30 | Pharmacyclics, Inc. | Mutations associated with resistance to inhibitors of bruton's tyrosine kinase (btk) |
JP6514114B2 (ja) | 2013-01-23 | 2019-05-15 | アルデイラ セラピューティクス, インコーポレイテッド | 毒性アルデヒド関連疾患および処置 |
CN111356451A (zh) | 2017-10-10 | 2020-06-30 | 奥尔德拉医疗公司 | 炎性病症的治疗 |
CN111053777A (zh) * | 2018-10-16 | 2020-04-24 | 正大天晴药业集团股份有限公司 | 伊布替尼的药物组合物及其应用 |
JP2022526917A (ja) | 2019-03-26 | 2022-05-27 | アルデイラ セラピューティクス, インコーポレイテッド | 眼科用製剤およびその使用 |
CN110272417B (zh) * | 2019-06-18 | 2021-07-13 | 五邑大学 | 2-甲基-1,8-萘啶类化合物及其制备方法与应用 |
CN110305128B (zh) * | 2019-07-31 | 2021-08-24 | 桂林医学院 | 5-氨基苯并[b][1,8]萘啶类化合物的制备方法和应用 |
CA3175856A1 (en) * | 2020-05-13 | 2021-11-18 | Todd Brady | Pharmaceutical formulations and uses thereof |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011146879A2 (en) * | 2010-05-20 | 2011-11-24 | University Of Rochester | Methods and compositions related to modulating autophagy |
US20120071497A1 (en) * | 2010-06-03 | 2012-03-22 | Pharmacyclics, Inc. | Methods of treating abc-dlbcl using inhibitors of bruton's tyrosine kinase |
NZ772688A (en) * | 2010-06-03 | 2022-09-30 | Pharmacyclics Llc | The use of inhibitors of bruton’s tyrosine kinase (btk) |
US20140206681A1 (en) * | 2013-01-23 | 2014-07-24 | Ronald M. Kim | Btk inhibitors |
US20160022683A1 (en) * | 2013-03-14 | 2016-01-28 | Pharmacyclics Llc | Combinations of bruton's tyrosine kinase inhibitors and cyp3a4 inhibitors |
CA2908375A1 (en) * | 2013-04-08 | 2014-10-16 | Pharmacyclics Llc | Ibrutinib combination therapy |
-
2015
- 2015-11-16 TW TW104137811A patent/TW201628622A/zh unknown
- 2015-11-17 EP EP15860051.0A patent/EP3220912A4/en not_active Withdrawn
- 2015-11-17 JP JP2017526490A patent/JP2017533944A/ja active Pending
- 2015-11-17 MX MX2017006464A patent/MX2017006464A/es unknown
- 2015-11-17 BR BR112017010262-5A patent/BR112017010262A2/pt not_active Application Discontinuation
- 2015-11-17 US US15/527,443 patent/US20170354655A1/en not_active Abandoned
- 2015-11-17 AU AU2015350136A patent/AU2015350136A1/en not_active Abandoned
- 2015-11-17 WO PCT/US2015/061091 patent/WO2016081460A1/en active Application Filing
- 2015-11-17 CN CN201580065011.0A patent/CN106999495A/zh active Pending
- 2015-11-17 CA CA2966542A patent/CA2966542A1/en not_active Abandoned
-
2018
- 2018-03-12 HK HK18103426.8A patent/HK1243929A1/zh unknown
Also Published As
Publication number | Publication date |
---|---|
US20170354655A1 (en) | 2017-12-14 |
TW201628622A (zh) | 2016-08-16 |
JP2017533944A (ja) | 2017-11-16 |
MX2017006464A (es) | 2018-08-09 |
EP3220912A4 (en) | 2018-06-20 |
BR112017010262A2 (pt) | 2018-07-03 |
CA2966542A1 (en) | 2016-05-26 |
AU2015350136A1 (en) | 2017-05-25 |
WO2016081460A1 (en) | 2016-05-26 |
CN106999495A (zh) | 2017-08-01 |
EP3220912A1 (en) | 2017-09-27 |
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