HK1244822A1 - 從色譜柱中連續洗脫產物的方法 - Google Patents

從色譜柱中連續洗脫產物的方法

Info

Publication number
HK1244822A1
HK1244822A1 HK18104098.3A HK18104098A HK1244822A1 HK 1244822 A1 HK1244822 A1 HK 1244822A1 HK 18104098 A HK18104098 A HK 18104098A HK 1244822 A1 HK1244822 A1 HK 1244822A1
Authority
HK
Hong Kong
Prior art keywords
product
chromatography columns
continuous elution
elution
continuous
Prior art date
Application number
HK18104098.3A
Other languages
English (en)
Inventor
Peter Schwan
Kerstin Baumarth
Martin Lobedann
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of HK1244822A1 publication Critical patent/HK1244822A1/zh

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/16—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the fluid carrier
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1864—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns
    • B01D15/1871—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns placed in series
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/42—Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
    • B01D15/424—Elution mode
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C12N15/1006—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
    • C12N15/101—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers by chromatography, e.g. electrophoresis, ion-exchange, reverse phase
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
    • B01D15/3804—Affinity chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/46—Flow patterns using more than one column
    • G01N30/461—Flow patterns using more than one column with serial coupling of separation columns

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
HK18104098.3A 2015-05-13 2018-03-26 從色譜柱中連續洗脫產物的方法 HK1244822A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15167518.8A EP3037513A1 (de) 2015-05-13 2015-05-13 Verfahren zur kontinuierlichen elution eines produktes von chromatographiesäulen
PCT/EP2016/060368 WO2016180797A1 (de) 2015-05-13 2016-05-10 Verfahren zur kontinuierlichen elution eines produktes von chromatographiesäulen

Publications (1)

Publication Number Publication Date
HK1244822A1 true HK1244822A1 (zh) 2018-08-17

Family

ID=53177194

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18104098.3A HK1244822A1 (zh) 2015-05-13 2018-03-26 從色譜柱中連續洗脫產物的方法

Country Status (16)

Country Link
US (1) US20180117495A1 (zh)
EP (2) EP3037513A1 (zh)
JP (1) JP6676073B2 (zh)
KR (1) KR20180004726A (zh)
CN (1) CN107683285A (zh)
AR (1) AR104573A1 (zh)
AU (1) AU2016259745B2 (zh)
BR (1) BR112017024339A2 (zh)
CA (1) CA2985679A1 (zh)
HK (1) HK1244822A1 (zh)
IL (1) IL255434A0 (zh)
MX (1) MX2017014516A (zh)
RU (1) RU2017143436A (zh)
SG (1) SG11201709192RA (zh)
TW (1) TWI679053B (zh)
WO (1) WO2016180797A1 (zh)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9458450B2 (en) 2012-03-15 2016-10-04 Flodesign Sonics, Inc. Acoustophoretic separation technology using multi-dimensional standing waves
US10967298B2 (en) 2012-03-15 2021-04-06 Flodesign Sonics, Inc. Driver and control for variable impedence load
US10704021B2 (en) 2012-03-15 2020-07-07 Flodesign Sonics, Inc. Acoustic perfusion devices
US9950282B2 (en) 2012-03-15 2018-04-24 Flodesign Sonics, Inc. Electronic configuration and control for acoustic standing wave generation
WO2015105955A1 (en) 2014-01-08 2015-07-16 Flodesign Sonics, Inc. Acoustophoresis device with dual acoustophoretic chamber
US11377651B2 (en) 2016-10-19 2022-07-05 Flodesign Sonics, Inc. Cell therapy processes utilizing acoustophoresis
US11021699B2 (en) 2015-04-29 2021-06-01 FioDesign Sonics, Inc. Separation using angled acoustic waves
US11708572B2 (en) 2015-04-29 2023-07-25 Flodesign Sonics, Inc. Acoustic cell separation techniques and processes
US11459540B2 (en) 2015-07-28 2022-10-04 Flodesign Sonics, Inc. Expanded bed affinity selection
US11474085B2 (en) 2015-07-28 2022-10-18 Flodesign Sonics, Inc. Expanded bed affinity selection
US11085035B2 (en) 2016-05-03 2021-08-10 Flodesign Sonics, Inc. Therapeutic cell washing, concentration, and separation utilizing acoustophoresis
US11214789B2 (en) 2016-05-03 2022-01-04 Flodesign Sonics, Inc. Concentration and washing of particles with acoustics
CN110494543A (zh) 2016-10-19 2019-11-22 弗洛设计声能学公司 通过声学的亲和细胞提取
WO2019118921A1 (en) 2017-12-14 2019-06-20 Flodesign Sonics, Inc. Acoustic transducer drive and controller
GB201908612D0 (en) * 2019-06-17 2019-07-31 Ge Healthcare Bio Sciences Ab A method for separating biomolecules
GB202003835D0 (en) * 2020-03-17 2020-04-29 Johnson Matthey Plc Chromatographic method for separating platinum group metals
AU2021293805A1 (en) 2020-06-16 2022-12-22 Boehringer Ingelheim International Gmbh A method of providing a homogeneous feed stream within a plug flow reactor
CN114660189A (zh) * 2020-12-24 2022-06-24 益海嘉里金龙鱼粮油食品股份有限公司 检测食用油中乙基麦芽酚的方法

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4434051A (en) * 1982-06-07 1984-02-28 Uop Inc. Multiple valve apparatus for simulated moving bed adsorption processes
DE19711173A1 (de) * 1997-03-18 1998-09-24 Sartorius Gmbh Verfahren und Anlage für die adsorptive Stofftrennung
US7108789B2 (en) * 2002-07-29 2006-09-19 Calgon Carbon Corporation High performance continuous reaction/separation process using a continuous liquid-solid contactor
US20060246537A1 (en) * 2005-04-29 2006-11-02 Jenkins Lauri L Multi-step process for the manufacture of therapeutic protein
EP1716900A1 (en) * 2005-04-29 2006-11-02 Eidgenössische Technische Hochschule Zürich Method and device for chromatographic purification
US7544293B2 (en) * 2005-09-26 2009-06-09 Semba Inc. Valve and process for interrupted continuous flow chromatography
EP1775001A1 (en) * 2005-10-13 2007-04-18 Xendo Holding B.V. Device for chromatographic separations
FR2898283B1 (fr) * 2006-03-08 2011-07-15 Novasep Procede et dispositif de separation de fractions d'un melange.
WO2008153472A1 (en) * 2007-06-15 2008-12-18 Ge Healthcare Bio-Sciences Ab Chromatography method
GB2452301A (en) 2007-08-30 2009-03-04 Ge Healthcare Bio Sciences Ab Sterilization Method
JP5600688B2 (ja) * 2009-01-06 2014-10-01 クロマコン アーゲー 多画分精製方法及びそのような方法のための装置
KR101152036B1 (ko) * 2010-04-27 2012-06-08 (주)셀트리온 컬럼 순환 및 시료 연속주입법을 이용한 단백질 ａ 크로마토그래피 정제 방법
CN103026220B (zh) * 2010-07-07 2014-12-24 通用电气健康护理生物科学股份公司 在一次性流体处理系统中的流体混合
CN103221105B (zh) * 2010-12-03 2015-11-25 通用电气健康护理生物科学股份公司 生物聚合物色谱的系统和工艺
US20130260419A1 (en) * 2010-12-06 2013-10-03 Thomas C. Ransohoff Continuous processing methods for biological products
WO2013083482A1 (en) * 2011-12-05 2013-06-13 Chromacon Ag Chromatographic method for the separation of fatty acid mixtures
EP2656892A1 (en) * 2012-04-23 2013-10-30 Merck Patent GmbH Chromatography method
EP2682168A1 (en) * 2012-07-02 2014-01-08 Millipore Corporation Purification of biological molecules
DK2772289T3 (en) * 2013-03-01 2015-08-10 Chromacon Ag Chromatographic method for the enrichment and isolation
SG10201709131UA (en) 2013-03-08 2017-12-28 Genzyme Corp Continuous purification of therapeutic proteins
US10099156B2 (en) * 2013-04-08 2018-10-16 Chromacon Ag Chromatographic purification method

Also Published As

Publication number Publication date
JP6676073B2 (ja) 2020-04-08
AU2016259745B2 (en) 2020-08-06
EP3037513A1 (de) 2016-06-29
WO2016180797A1 (de) 2016-11-17
MX2017014516A (es) 2018-03-15
BR112017024339A2 (pt) 2018-07-31
CA2985679A1 (en) 2016-11-17
EP3294857A1 (de) 2018-03-21
US20180117495A1 (en) 2018-05-03
SG11201709192RA (en) 2017-12-28
IL255434A0 (en) 2017-12-31
RU2017143436A3 (zh) 2019-11-28
CN107683285A (zh) 2018-02-09
AU2016259745A1 (en) 2017-11-30
JP2018524146A (ja) 2018-08-30
TWI679053B (zh) 2019-12-11
TW201709962A (zh) 2017-03-16
KR20180004726A (ko) 2018-01-12
RU2017143436A (ru) 2019-06-17
AR104573A1 (es) 2017-08-02

Similar Documents

Publication Publication Date Title
HK1244822A1 (zh) 從色譜柱中連續洗脫產物的方法
PL3411599T3 (pl) Zestaw paneli do zmontowanego produktu
IL250165A0 (en) Cation exchange chromatographic support and method for using it
LT3265198T (lt) Giminingumo chromatografijos matricų dezinfekavimo būdas
AP2016009358A0 (en) Process for fractionation of oligosaccharides from agri-waste
HUE064544T2 (hu) Eljárás kromatográfiai termékek összetételének beállítására
GB201721476D0 (en) A method for proparation of a separation matrix
GB2543387B (en) Process control alarm auditing
EP3215640B8 (en) Chromatographic sequential simulated moving bed fractionation method of a feedstock
GB201506117D0 (en) Method for chromatography
ZA201706221B (en) Method for producing a tablet which comprises a sample material
GB201600171D0 (en) A method and apparatus for packing a chromatography column
GB201506113D0 (en) Method for chromatography
GB201504695D0 (en) Chromatography columns and processes
ZA201708767B (en) Apparatus for dividing horticultural products
GB201519361D0 (en) Gas chromatography apparatus
ZA201708614B (en) Apparatus for selecting horticultural products
ZA201707922B (en) Multi-step process for no production
GB2548650B (en) Conical heater assembly for a gas chromatography column
GB2553115B (en) Distillation columns
GB2527167B (en) Method of fraction collection for a liquid chromatography system
GB201610792D0 (en) Method for packing chromatography columns
GB201906678D0 (en) Chromatography column
GB201517282D0 (en) A chromatography system and a method therefor
GB2536726B (en) Chromatography columns and their operation