HK1244821A1 - 用於治療和診斷1型糖尿病中使用的肽 - Google Patents
用於治療和診斷1型糖尿病中使用的肽Info
- Publication number
- HK1244821A1 HK1244821A1 HK18104063.4A HK18104063A HK1244821A1 HK 1244821 A1 HK1244821 A1 HK 1244821A1 HK 18104063 A HK18104063 A HK 18104063A HK 1244821 A1 HK1244821 A1 HK 1244821A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- diabetes
- peptides
- diagnosis
- treatment
- type
- Prior art date
Links
- 206010067584 Type 1 diabetes mellitus Diseases 0.000 title 1
- 238000003745 diagnosis Methods 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5047—Cells of the immune system
- G01N33/505—Cells of the immune system involving T-cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4747—Apoptosis related proteins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
- C07K16/246—IL-2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/249—Interferons
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5082—Supracellular entities, e.g. tissue, organisms
- G01N33/5088—Supracellular entities, e.g. tissue, organisms of vertebrates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
- G01N33/6866—Interferon
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
- G01N33/6869—Interleukin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/52—Assays involving cytokines
- G01N2333/521—Chemokines
- G01N2333/522—Alpha-chemokines, e.g. NAP-2, ENA-78, GRO-alpha/MGSA/NAP-3, GRO-beta/MIP-2alpha, GRO-gamma/MIP-2beta, IP-10, GCP-2, MIG, PBSF, PF-4 or KC
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/52—Assays involving cytokines
- G01N2333/54—Interleukins [IL]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/52—Assays involving cytokines
- G01N2333/555—Interferons [IFN]
- G01N2333/57—IFN-gamma
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/04—Endocrine or metabolic disorders
- G01N2800/042—Disorders of carbohydrate metabolism, e.g. diabetes, glucose metabolism
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201462082823P | 2014-11-21 | 2014-11-21 | |
PCT/US2015/061931 WO2016081869A2 (en) | 2014-11-21 | 2015-11-20 | Peptides for use in treatment and diagnosis of type 1 diabetes |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1244821A1 true HK1244821A1 (zh) | 2018-08-17 |
Family
ID=55024215
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK18104063.4A HK1244821A1 (zh) | 2014-11-21 | 2018-03-23 | 用於治療和診斷1型糖尿病中使用的肽 |
Country Status (7)
Country | Link |
---|---|
US (2) | US10473647B1 (zh) |
EP (1) | EP3221344A2 (zh) |
CN (1) | CN107531767A (zh) |
AU (1) | AU2015349728A1 (zh) |
CA (1) | CA2968422A1 (zh) |
HK (1) | HK1244821A1 (zh) |
WO (1) | WO2016081869A2 (zh) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2019104391A1 (en) * | 2017-12-01 | 2019-06-06 | St Vincent's Institute Of Medical Research | Type 1 diabetes treatment |
EP4010353A4 (en) * | 2019-08-05 | 2023-08-23 | Icahn School of Medicine at Mount Sinai | PEPTIDES THAT BLOCK THE PRESENTATION OF ANTIGEN ISLAND PEPTIDES BY HLA-DQ8 AND METHODS OF TREATING TYPE 1 DIABETES |
Family Cites Families (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5840836A (en) * | 1989-02-17 | 1998-11-24 | Bayer Corporation | Pancreatic islet cell antigens obtained by molecular cloning |
US5674978A (en) | 1990-09-21 | 1997-10-07 | The Regents Of The University Of California | Peptides derived from glutamic acid decarboxylase |
US5998366A (en) | 1990-09-21 | 1999-12-07 | The Regents Of The University Of California | Method for ameliorating glutamic acid decarboxylase associated autoimmune disorders |
EP0852004B1 (en) | 1995-10-11 | 2011-01-19 | Luminex Corporation | Multiplexed analysis of clinical specimens |
US6410252B1 (en) | 1995-12-22 | 2002-06-25 | Case Western Reserve University | Methods for measuring T cell cytokines |
US5939281A (en) | 1996-09-16 | 1999-08-17 | Case Western Reserve University | Detecting alloreactivity |
GB9624456D0 (en) | 1996-11-25 | 1997-01-15 | Isis Innovation | Assay method |
FR2764989B1 (fr) | 1997-06-20 | 1999-08-27 | Pasteur Sanofi Diagnostics | Procede de dosage du c-peptide |
IL135593A (en) | 1997-10-14 | 2004-06-01 | Luminex Corp | Precisely fluorescently painted polymeric microspheres and methods for making and using them |
AUPP320998A0 (en) * | 1998-04-27 | 1998-05-21 | Walter And Eliza Hall Institute Of Medical Research, The | Tyrosine phosphatase IA-2 T-cell epitopes |
GB9923306D0 (en) | 1999-10-01 | 1999-12-08 | Isis Innovation | Diagnostic and therapeutic epitope, and transgenic plant |
IL132611A0 (en) | 1999-10-27 | 2001-03-19 | Yeda Res & Dev | Synthetic genes and polypeptides and pharmaceutical compositions comprising them |
US20030166589A1 (en) | 2001-06-05 | 2003-09-04 | Nathan Karin | Method and pharmaceutical composition for the treatment of multiple sclerosis |
US8148171B2 (en) | 2001-10-09 | 2012-04-03 | Luminex Corporation | Multiplexed analysis of clinical specimens apparatus and methods |
GB0212885D0 (en) | 2002-06-05 | 2002-07-17 | Isis Innovation | Therapeutic epitopes and uses thereof |
US20050053954A1 (en) | 2002-11-01 | 2005-03-10 | Brennan John D. | Multicomponent protein microarrays |
GB0402129D0 (en) | 2004-01-30 | 2004-03-03 | King S College London | Therapeutic and diagnostic peptides |
WO2005105129A2 (en) | 2004-04-28 | 2005-11-10 | Btg International Limited | Epitopes related to coeliac disease |
WO2006007667A1 (en) | 2004-07-23 | 2006-01-26 | The Walter And Eliza Hall Institute Of Medical Research | Therapeutic and diagnostic agents |
JP5042859B2 (ja) | 2005-01-20 | 2012-10-03 | ルミネックス コーポレーション | 蛍光ベースの応用で使用される磁性ミクロスフェア |
CN102621053B (zh) | 2005-09-21 | 2015-05-06 | 卢米尼克斯股份有限公司 | 图像数据处理的方法和系统 |
US8378072B2 (en) | 2006-04-13 | 2013-02-19 | Declion Pharmaceuticals, Inc. | Methods for designing and synthesizing directed sequence polymer compositions via the directed expansion of epitope permeability |
US8296088B2 (en) | 2006-06-02 | 2012-10-23 | Luminex Corporation | Systems and methods for performing measurements of one or more materials |
IN2015DN03125A (zh) | 2006-09-05 | 2015-10-02 | Hvidovre Hospital | |
US20120214963A1 (en) | 2011-02-23 | 2012-08-23 | Elona Biotechnologies | Aspart proinsulin compositions and methods of producing aspart insulin analogs therefrom |
WO2008100791A1 (en) | 2007-02-16 | 2008-08-21 | Rules-Based Medicine, Inc. | Methods and kits for the diagnosis of sickle cell |
GB0712670D0 (en) * | 2007-06-29 | 2007-08-08 | King S College London | Isolated peptides and uses thereof |
EP2977053B1 (en) | 2008-11-30 | 2017-07-05 | Immusant, Inc. | Compositions and methods for treatment of celiac disease |
AU2009335712B2 (en) | 2008-12-19 | 2015-09-17 | Indiana University Research And Technology Corporation | Insulin analogs |
US8274656B2 (en) | 2010-06-30 | 2012-09-25 | Luminex Corporation | Apparatus, system, and method for increasing measurement accuracy in a particle imaging device |
WO2012007950A2 (en) | 2010-07-15 | 2012-01-19 | Technion Research & Development Foundation Ltd. | Isolated high affinity entities with t-cell receptor like specificity towards native complexes of mhc class ii and diabetes-associated autoantigenic peptides |
CN103619880A (zh) | 2011-04-29 | 2014-03-05 | 百时美施贵宝公司 | Ip-10抗体剂量递增方法 |
US20140342936A1 (en) | 2011-12-15 | 2014-11-20 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Methods and kits for diagnosing latent tuberculosis infection |
CA2906044A1 (en) | 2013-03-14 | 2014-09-25 | Immusant, Inc. | Placebo-controlled gluten challenge method |
WO2015038624A1 (en) | 2013-09-10 | 2015-03-19 | Immusant, Inc. | Dosage of a gluten peptide composition |
EP3046576A4 (en) | 2013-09-20 | 2017-07-12 | Immusant Inc. | Compositions and methods related to oat sensitivity |
EP3134425A4 (en) | 2014-04-24 | 2018-06-20 | Immusant Inc. | Compositions comprising gluten peptides and uses thereof |
US20170059582A1 (en) | 2014-04-24 | 2017-03-02 | Immusant, Inc. | Methods for diagnosing celiac disease using circulating cytokines/chemokines |
US20170097346A1 (en) | 2014-04-24 | 2017-04-06 | Immusant, Inc. | Use of interleukin-2 for diagnosis of celiac disease |
AU2015323979A1 (en) | 2014-09-29 | 2017-05-18 | Immusant, Inc. | Use of HLA genetic status to assess or select treatment of celiac disease |
-
2015
- 2015-11-20 US US15/528,172 patent/US10473647B1/en not_active Expired - Fee Related
- 2015-11-20 WO PCT/US2015/061931 patent/WO2016081869A2/en active Application Filing
- 2015-11-20 EP EP15816558.9A patent/EP3221344A2/en not_active Withdrawn
- 2015-11-20 CA CA2968422A patent/CA2968422A1/en not_active Abandoned
- 2015-11-20 AU AU2015349728A patent/AU2015349728A1/en not_active Abandoned
- 2015-11-20 CN CN201580073016.8A patent/CN107531767A/zh active Pending
-
2018
- 2018-03-23 HK HK18104063.4A patent/HK1244821A1/zh unknown
-
2019
- 2019-10-08 US US16/596,446 patent/US20200141924A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CN107531767A (zh) | 2018-01-02 |
CA2968422A1 (en) | 2016-05-26 |
WO2016081869A2 (en) | 2016-05-26 |
US20200141924A1 (en) | 2020-05-07 |
EP3221344A2 (en) | 2017-09-27 |
AU2015349728A1 (en) | 2017-07-13 |
WO2016081869A3 (en) | 2016-07-14 |
US10473647B1 (en) | 2019-11-12 |
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