HK1243706A1 - 用於製備(5-十四烷氧基)呋喃-2-甲酸2-((2-乙氧基-2-氧代乙基)(甲基)氨基)-2-氧代乙酯的合成方法 - Google Patents

用於製備(5-十四烷氧基)呋喃-2-甲酸2-((2-乙氧基-2-氧代乙基)(甲基)氨基)-2-氧代乙酯的合成方法

Info

Publication number
HK1243706A1
HK1243706A1 HK18103280.3A HK18103280A HK1243706A1 HK 1243706 A1 HK1243706 A1 HK 1243706A1 HK 18103280 A HK18103280 A HK 18103280A HK 1243706 A1 HK1243706 A1 HK 1243706A1
Authority
HK
Hong Kong
Prior art keywords
oxoethyl
tetradecyloxy
furan
carboxylate
ethoxy
Prior art date
Application number
HK18103280.3A
Other languages
English (en)
Inventor
Adrian Shaw Anthony
Khumtaveeporn Kanjai
Krasik Pavel
Original Assignee
Dermira Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dermira Inc filed Critical Dermira Inc
Publication of HK1243706A1 publication Critical patent/HK1243706A1/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/68Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Furan Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK18103280.3A 2015-02-05 2018-03-08 用於製備(5-十四烷氧基)呋喃-2-甲酸2-((2-乙氧基-2-氧代乙基)(甲基)氨基)-2-氧代乙酯的合成方法 HK1243706A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562112569P 2015-02-05 2015-02-05
PCT/US2016/016616 WO2016126973A1 (en) 2015-02-05 2016-02-04 Synthetic process for preparing 2-((2-ethoxy-2-oxoethyl)(methyl)amino)-2-oxoethyl 5-tetradecyloxy)furan-2-carboxylate

Publications (1)

Publication Number Publication Date
HK1243706A1 true HK1243706A1 (zh) 2018-07-20

Family

ID=55404838

Family Applications (1)

Application Number Title Priority Date Filing Date
HK18103280.3A HK1243706A1 (zh) 2015-02-05 2018-03-08 用於製備(5-十四烷氧基)呋喃-2-甲酸2-((2-乙氧基-2-氧代乙基)(甲基)氨基)-2-氧代乙酯的合成方法

Country Status (10)

Country Link
US (2) US9487497B2 (zh)
EP (1) EP3253742B1 (zh)
JP (1) JP6626113B2 (zh)
KR (1) KR20170113590A (zh)
CN (1) CN107406400B (zh)
AU (1) AU2016215228A1 (zh)
CA (1) CA2975877A1 (zh)
ES (1) ES2802465T3 (zh)
HK (1) HK1243706A1 (zh)
WO (1) WO2016126973A1 (zh)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20170113590A (ko) * 2015-02-05 2017-10-12 더미라, 인코포레이티드 2-((2-에톡시-2-옥소에틸)(메틸)아미노)-2-옥소에틸 5-테트라데실옥시)푸란-2-카르복실레이트의 제조를 위한 합성 방법
EP3490549A1 (en) * 2016-07-26 2019-06-05 Dermira, Inc. Dermatological formulations of 2-(2-ethoxy-2-oxoethyl)(methyl)amino-2-oxoethyl 5-(tetradecyloxy)furan-2-carboxylate

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4033563A1 (de) 1990-10-22 1992-04-23 Henkel Kgaa Antiseborrhoische zubereitungen
BRPI0312413A2 (pt) * 2002-07-01 2016-08-02 Fasgen Llc compostos, composições farmacêuticas contendo os mesmos, e método de utilização para os mesmos
US20100204317A1 (en) 2006-11-03 2010-08-12 Qlt Inc. Methods of treating dermatological disorders or conditions
RU2561729C2 (ru) 2009-07-08 2015-09-10 Дермира (Канада), Инк. Аналоги tofa, применимые при лечении дерматологических расстройств или состояний
US8697739B2 (en) * 2010-07-29 2014-04-15 Novartis Ag Bicyclic acetyl-CoA carboxylase inhibitors and uses thereof
KR20170113590A (ko) * 2015-02-05 2017-10-12 더미라, 인코포레이티드 2-((2-에톡시-2-옥소에틸)(메틸)아미노)-2-옥소에틸 5-테트라데실옥시)푸란-2-카르복실레이트의 제조를 위한 합성 방법

Also Published As

Publication number Publication date
ES2802465T3 (es) 2021-01-19
JP6626113B2 (ja) 2019-12-25
US20160229826A1 (en) 2016-08-11
US9487497B2 (en) 2016-11-08
EP3253742B1 (en) 2020-04-08
AU2016215228A1 (en) 2017-08-10
CN107406400A (zh) 2017-11-28
WO2016126973A1 (en) 2016-08-11
JP2018504442A (ja) 2018-02-15
KR20170113590A (ko) 2017-10-12
CN107406400B (zh) 2020-08-04
US9745277B2 (en) 2017-08-29
US20170022176A1 (en) 2017-01-26
CA2975877A1 (en) 2016-08-11
EP3253742A1 (en) 2017-12-13

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