HK1231479A1 - -二甲氧基喹唑啉- -基 氧基 -二甲基苯並呋喃- -甲酰胺晶型 - Google Patents

-二甲氧基喹唑啉- -基 氧基 -二甲基苯並呋喃- -甲酰胺晶型

Info

Publication number
HK1231479A1
HK1231479A1 HK17105224.8A HK17105224A HK1231479A1 HK 1231479 A1 HK1231479 A1 HK 1231479A1 HK 17105224 A HK17105224 A HK 17105224A HK 1231479 A1 HK1231479 A1 HK 1231479A1
Authority
HK
Hong Kong
Prior art keywords
dimethoxyquinazolin
dimethylbenzofuran
carboxamide
oxy
crystalline forms
Prior art date
Application number
HK17105224.8A
Other languages
English (en)
Inventor
Zhenping Wu
Wenji Li
Yuping Chu
Original Assignee
Hutchison Medipharma Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=55458346&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1231479(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hutchison Medipharma Ltd filed Critical Hutchison Medipharma Ltd
Publication of HK1231479A1 publication Critical patent/HK1231479A1/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/86Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK17105224.8A 2014-09-10 2017-05-23 -二甲氧基喹唑啉- -基 氧基 -二甲基苯並呋喃- -甲酰胺晶型 HK1231479A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN201410456350.9A CN105461702A (zh) 2014-09-10 2014-09-10 6-(6,7-二甲氧基喹唑啉-4-基氧基)-n,2-二甲基苯并呋喃-3-甲酰胺晶型
PCT/CN2015/089035 WO2016037550A1 (en) 2014-09-10 2015-09-07 Crystalline forms of 6- ( (6, 7-dimethoxyquinazolin-4-yl) oxy) -n,2-dimethylbenzofuran-3-carboxamide

Publications (1)

Publication Number Publication Date
HK1231479A1 true HK1231479A1 (zh) 2017-12-22

Family

ID=55458346

Family Applications (1)

Application Number Title Priority Date Filing Date
HK17105224.8A HK1231479A1 (zh) 2014-09-10 2017-05-23 -二甲氧基喹唑啉- -基 氧基 -二甲基苯並呋喃- -甲酰胺晶型

Country Status (31)

Country Link
US (4) US10519142B2 (zh)
EP (1) EP3191475B1 (zh)
JP (2) JP6655608B2 (zh)
KR (2) KR20170042662A (zh)
CN (3) CN105461702A (zh)
AU (1) AU2015316010B2 (zh)
BR (1) BR112017004000B1 (zh)
CA (1) CA2958666C (zh)
CL (1) CL2017000540A1 (zh)
CY (1) CY1123892T1 (zh)
DK (1) DK3191475T3 (zh)
EA (1) EA034730B1 (zh)
ES (1) ES2819242T3 (zh)
HK (1) HK1231479A1 (zh)
HR (1) HRP20201501T1 (zh)
HU (1) HUE050580T2 (zh)
IL (1) IL250647B (zh)
LT (1) LT3191475T (zh)
MX (1) MX370791B (zh)
MY (1) MY176618A (zh)
PE (1) PE20170661A1 (zh)
PH (1) PH12017500451A1 (zh)
PL (1) PL3191475T3 (zh)
PT (1) PT3191475T (zh)
RS (1) RS60829B1 (zh)
SG (1) SG11201701544UA (zh)
SI (1) SI3191475T1 (zh)
TW (1) TWI718105B (zh)
UA (1) UA120371C2 (zh)
WO (1) WO2016037550A1 (zh)
ZA (1) ZA201701320B (zh)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105461702A (zh) * 2014-09-10 2016-04-06 和记黄埔医药(上海)有限公司 6-(6,7-二甲氧基喹唑啉-4-基氧基)-n,2-二甲基苯并呋喃-3-甲酰胺晶型
US11286259B2 (en) 2017-09-29 2022-03-29 Hangzhou Solipharma Co., Ltd. Co-crystals of ribociclib and co-crystals of ribociclib monosuccinate, preparation method therefor, compositions thereof, and uses thereof
US11236077B2 (en) 2018-03-30 2022-02-01 Hangzhou Solipharma Co., Ltd. Fruquintinib eutectic crystal, preparation method therefor, composition, and uses thereof
CN111184698A (zh) * 2018-11-15 2020-05-22 和记黄埔医药(上海)有限公司 呋喹替尼制剂及其应用
CN113330166B (zh) 2019-03-28 2023-05-05 住友重机械工业株式会社 挖土机
CN113200966B (zh) * 2021-04-06 2022-07-22 深圳大学 一种呋喹替尼衍生物、药物组合物和用途
GB202211142D0 (en) * 2022-07-29 2022-09-14 Macfarlan Smith Ltd Polymorphs, co-crystals and solvates of fruquintinib, processes for the preparation and use thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7829574B2 (en) 2008-05-09 2010-11-09 Hutchison Medipharma Enterprises Limited Substituted quinazoline compounds and their use in treating angiogenesis-related diseases
CN101575333B (zh) * 2008-05-09 2011-06-22 和记黄埔医药(上海)有限公司 一种喹唑啉衍生物及其医药用途
CN105461702A (zh) * 2014-09-10 2016-04-06 和记黄埔医药(上海)有限公司 6-(6,7-二甲氧基喹唑啉-4-基氧基)-n,2-二甲基苯并呋喃-3-甲酰胺晶型

Also Published As

Publication number Publication date
BR112017004000A2 (pt) 2017-12-05
AU2015316010A8 (en) 2017-05-11
TWI718105B (zh) 2021-02-11
SI3191475T1 (sl) 2021-02-26
RS60829B1 (sr) 2020-10-30
TW201609715A (zh) 2016-03-16
EA201790275A1 (ru) 2017-10-31
CY1123892T1 (el) 2022-03-24
HRP20201501T1 (hr) 2020-12-25
EP3191475A4 (en) 2018-10-03
AU2015316010A1 (en) 2017-04-27
KR20190018056A (ko) 2019-02-20
MY176618A (en) 2020-08-18
NZ729884A (en) 2020-09-25
ES2819242T3 (es) 2021-04-15
DK3191475T3 (da) 2020-09-28
US10519142B2 (en) 2019-12-31
MX2017002913A (es) 2017-06-06
CN111018846A (zh) 2020-04-17
CA2958666C (en) 2020-10-06
CN105461702A (zh) 2016-04-06
AU2015316010B2 (en) 2018-06-14
CN111018846B (zh) 2023-06-06
CN106604919A (zh) 2017-04-26
JP6655608B2 (ja) 2020-02-26
SG11201701544UA (en) 2017-03-30
JP2017526710A (ja) 2017-09-14
IL250647B (en) 2020-11-30
US11958838B2 (en) 2024-04-16
CN106604919B (zh) 2019-11-15
KR20170042662A (ko) 2017-04-19
PE20170661A1 (es) 2017-05-18
US20210276983A1 (en) 2021-09-09
US20240279208A1 (en) 2024-08-22
IL250647A0 (en) 2017-04-30
US20170283399A1 (en) 2017-10-05
EP3191475B1 (en) 2020-07-29
PT3191475T (pt) 2020-09-04
CA2958666A1 (en) 2016-03-17
LT3191475T (lt) 2020-10-12
KR102221722B1 (ko) 2021-03-03
MX370791B (es) 2020-01-08
WO2016037550A1 (en) 2016-03-17
PL3191475T3 (pl) 2021-01-11
UA120371C2 (uk) 2019-11-25
CL2017000540A1 (es) 2017-09-15
BR112017004000B1 (pt) 2023-10-24
EP3191475A1 (en) 2017-07-19
US11046674B2 (en) 2021-06-29
ZA201701320B (en) 2020-07-29
US20200140420A1 (en) 2020-05-07
JP2019065019A (ja) 2019-04-25
PH12017500451A1 (en) 2017-07-31
HUE050580T2 (hu) 2020-12-28
EA034730B1 (ru) 2020-03-13

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