HK1223659A1 - 基於可多重標籤的報告系統 - Google Patents
基於可多重標籤的報告系統Info
- Publication number
- HK1223659A1 HK1223659A1 HK16111996.3A HK16111996A HK1223659A1 HK 1223659 A1 HK1223659 A1 HK 1223659A1 HK 16111996 A HK16111996 A HK 16111996A HK 1223659 A1 HK1223659 A1 HK 1223659A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- multiplexable
- tag
- reporter system
- based reporter
- reporter
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361834926P | 2013-06-14 | 2013-06-14 | |
| PCT/US2014/042096 WO2014201232A2 (en) | 2013-06-14 | 2014-06-12 | Multiplexable tag-based reporter system |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1223659A1 true HK1223659A1 (zh) | 2017-08-04 |
Family
ID=51179156
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK16111996.3A HK1223659A1 (zh) | 2013-06-14 | 2016-10-18 | 基於可多重標籤的報告系統 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20140371088A1 (de) |
| EP (2) | EP3434784A1 (de) |
| JP (1) | JP2016521575A (de) |
| AU (1) | AU2014278152A1 (de) |
| CA (1) | CA2914816A1 (de) |
| HK (1) | HK1223659A1 (de) |
| WO (1) | WO2014201232A2 (de) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2324503T3 (es) * | 1997-04-10 | 2009-08-07 | Stichting Katholieke Universiteit University Medical Centre Nijmegen | Pca3, genes pca3 y metodos de uso. |
| US10942184B2 (en) | 2012-10-23 | 2021-03-09 | Caris Science, Inc. | Aptamers and uses thereof |
| US20160042120A1 (en) | 2014-08-08 | 2016-02-11 | Nanostring Technologies, Inc. | Methods for deconvolution of mixed cell populations using gene expression data |
| CA2968519C (en) | 2014-11-24 | 2024-01-09 | Nanostring Technologies, Inc. | Methods and apparatuses for gene purification and imaging |
| US20180066262A1 (en) | 2015-03-09 | 2018-03-08 | Caris Science, Inc. | Oligonucleotide probes and uses thereof |
| AU2016287499B2 (en) | 2015-06-29 | 2022-08-04 | Caris Science, Inc. | Therapeutic oligonucleotides |
| EP3317425A1 (de) * | 2015-06-30 | 2018-05-09 | Nanostring Technologies, Inc. | Verfahren und kits zur gleichzeitigen detektion von gen- oder proteinexpression in mehreren probentypen mit selbstassemblierenden fluoreszierenden barcode-nanoreportern |
| JP6971218B2 (ja) | 2015-07-17 | 2021-11-24 | ナノストリング テクノロジーズ，インコーポレイティド | 横断組織切片のユーザー定義領域における遺伝子発現の同時定量 |
| CA2992480A1 (en) | 2015-07-17 | 2017-01-26 | Nanostring Technologies, Inc. | Simultaneous quantification of a plurality of proteins in a user-defined region of a cross-sectioned tissue |
| WO2017019918A1 (en) | 2015-07-28 | 2017-02-02 | Caris Science, Inc. | Targeted oligonucleotides |
| JP2018526009A (ja) * | 2015-09-03 | 2018-09-13 | ナノストリング テクノロジーズ，インコーポレイティド | ヌクレオチド１個の分解能を有する多価プローブ |
| EP3430137A4 (de) | 2016-03-18 | 2019-11-06 | Caris Science, Inc. | Oligonukleotidsonden und verwendungen davon |
| SG11201809913PA (en) * | 2016-05-16 | 2018-12-28 | Nanostring Technologies Inc | Methods for detecting target nucleic acids in a sample |
| CA3025486A1 (en) | 2016-05-25 | 2017-11-30 | Caris Science, Inc. | Oligonucleotide probes and uses thereof |
| WO2018093976A1 (en) * | 2016-11-16 | 2018-05-24 | Nanopore Diagnostics, Llc | Analysis of nucleic acids using probe with non-linear tag |
| KR102187291B1 (ko) | 2016-11-21 | 2020-12-07 | 나노스트링 테크놀로지스, 인크. | 화학적 조성물 및 이것을 사용하는 방법 |
| WO2019023551A1 (en) * | 2017-07-28 | 2019-01-31 | Nanostring Technologies, Inc. | IMMUNO-ONCOLOGY BIOMARKERS AND METHODS OF USE |
| WO2019104070A1 (en) | 2017-11-21 | 2019-05-31 | Nanostring Technologies, Inc. | O-nitrobenzyl photocleavable bifunctional linker |
| CN112154216A (zh) | 2018-02-12 | 2020-12-29 | 纳米线科技公司 | 生物分子探针以及检测基因和蛋白表达的方法 |
| WO2019213478A1 (en) | 2018-05-04 | 2019-11-07 | Nanostring Technologies, Inc. | Gene expression assay for measurement of dna mismatch repair deficiency |
| US11549139B2 (en) | 2018-05-14 | 2023-01-10 | Nanostring Technologies, Inc. | Chemical compositions and methods of using same |
| JP2021524744A (ja) | 2018-05-21 | 2021-09-16 | ナノストリング テクノロジーズ，インコーポレイティド | 分子遺伝子シグネチャーとその使用方法 |
| US11624125B2 (en) * | 2018-09-25 | 2023-04-11 | Northwestern University | Stabilization of colloidal crystals engineered with nucleic acid |
| SG11202111871WA (en) * | 2019-05-03 | 2021-11-29 | Meso Scale Technologies Llc | Kits for detecting one or more target nucleic acid analytes in a sample and methods of making and using the same |
| US20210254140A1 (en) | 2020-02-17 | 2021-08-19 | 10X Genomics, Inc. | Situ analysis of chromatin interaction |
| EP4168578B1 (de) | 2020-06-18 | 2024-08-07 | Bruker Spatial Biology, Inc. | Zusammensetzungen und verfahren zur in-situ-einzelzellenanalyse unter verwendung von enzymatischer nukleinsäureverlängerung |
| EP4012046A1 (de) | 2020-12-11 | 2022-06-15 | 10X Genomics, Inc. | Verfahren und zusammensetzungen zur multimodalen in-situ-analyse |
| EP4284945A1 (de) | 2021-01-26 | 2023-12-06 | 10X Genomics, Inc. | Nukleinsäureanalogsonden zur in-situ-analyse |
| WO2022187366A1 (en) | 2021-03-03 | 2022-09-09 | 10X Genomics, Inc. | Analyte detection in situ using nucleic acid origami |
| US20240279723A1 (en) | 2021-06-17 | 2024-08-22 | Nanostring Technologies, Inc. | Compositions and methods for in situ single cell analysis using enzymatic nucleic acid extension |
| EP4370896A1 (de) | 2021-07-13 | 2024-05-22 | 10X Genomics, Inc. | Verfahren zur herstellung einer polymerisierten matrix mit steuerbarer dicke |
| US20230057571A1 (en) | 2021-08-03 | 2023-02-23 | 10X Genomics, Inc. | Nucleic acid concatemers and methods for stabilizing and/or compacting the same |
| WO2023141588A1 (en) | 2022-01-21 | 2023-07-27 | 10X Genomics, Inc. | Multiple readout signals for analyzing a sample |
| WO2023229988A1 (en) | 2022-05-23 | 2023-11-30 | 10X Genomics, Inc. | Tissue sample mold |
| WO2024102736A1 (en) | 2022-11-08 | 2024-05-16 | 10X Genomics, Inc. | Immobilization methods and compositions for in situ detection |
| US20240158852A1 (en) | 2022-11-16 | 2024-05-16 | 10X Genomics, Inc. | Methods and compositions for assessing performance of in situ assays |
| WO2024130203A1 (en) | 2022-12-16 | 2024-06-20 | 10X Genomics, Inc. | Methods and compositions for assessing performance |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4868105A (en) * | 1985-12-11 | 1989-09-19 | Chiron Corporation | Solution phase nucleic acid sandwich assay |
| US5137819A (en) | 1988-07-08 | 1992-08-11 | University Of British Columbia | Cellulose binding fusion proteins for immobilization and purification of polypeptides |
| US5293050A (en) | 1993-03-25 | 1994-03-08 | International Business Machines Corporation | Semiconductor quantum dot light emitting/detecting devices |
| US5496934A (en) | 1993-04-14 | 1996-03-05 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Nucleic acids encoding a cellulose binding domain |
| US5681697A (en) * | 1993-12-08 | 1997-10-28 | Chiron Corporation | Solution phase nucleic acid sandwich assays having reduced background noise and kits therefor |
| FR2716263B1 (fr) | 1994-02-11 | 1997-01-17 | Pasteur Institut | Procédé d'alignement de macromolécules par passage d'un ménisque et applications dans un procédé de mise en évidence, séparation et/ou dosage d'une macromolécule dans un échantillon. |
| FR2737574B1 (fr) | 1995-08-03 | 1997-10-24 | Pasteur Institut | Appareillage d'alignement parallele de macromolecules et utilisation |
| FR2755149B1 (fr) | 1996-10-30 | 1999-01-15 | Pasteur Institut | Procede de diagnostic de maladies genetiques par peignage moleculaire et coffret de diagnostic |
| US20080038725A1 (en) * | 2005-06-20 | 2008-02-14 | Yuling Luo | Methods of detecting nucleic acids in individual cells and of identifying rare cells from large heterogeneous cell populations |
| ES2374788T3 (es) * | 2005-12-23 | 2012-02-22 | Nanostring Technologies, Inc. | Nanoinformadores y métodos para su producción y uso. |
| US7615351B2 (en) * | 2006-12-01 | 2009-11-10 | Panomics, Inc. | Two stage nucleic acid amplification using an amplification oligomer |
| CA2687292C (en) * | 2007-04-10 | 2017-07-04 | Nanostring Technologies, Inc. | Methods and computer systems for identifying target-specific sequences for use in nanoreporters |
| CA2733609C (en) * | 2008-08-14 | 2018-03-06 | Nanostring Technologies, Inc. | Stable nanoreporters |
| EP2630260B1 (de) * | 2010-10-21 | 2015-11-18 | Advanced Cell Diagnostics, Inc. | Hochsensitives verfahren für den in-situ-nachweis von nukleinsäuren |
-
2014
- 2014-06-12 WO PCT/US2014/042096 patent/WO2014201232A2/en active Application Filing
- 2014-06-12 AU AU2014278152A patent/AU2014278152A1/en not_active Abandoned
- 2014-06-12 EP EP18176103.2A patent/EP3434784A1/de not_active Ceased
- 2014-06-12 US US14/303,236 patent/US20140371088A1/en not_active Abandoned
- 2014-06-12 CA CA2914816A patent/CA2914816A1/en not_active Abandoned
- 2014-06-12 EP EP14739298.9A patent/EP3008209A2/de not_active Ceased
- 2014-06-12 JP JP2016519644A patent/JP2016521575A/ja not_active Ceased
-
2016
- 2016-10-18 HK HK16111996.3A patent/HK1223659A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20140371088A1 (en) | 2014-12-18 |
| WO2014201232A3 (en) | 2015-06-18 |
| CA2914816A1 (en) | 2014-12-18 |
| EP3434784A1 (de) | 2019-01-30 |
| EP3008209A2 (de) | 2016-04-20 |
| AU2014278152A1 (en) | 2015-12-24 |
| WO2014201232A2 (en) | 2014-12-18 |
| JP2016521575A (ja) | 2016-07-25 |
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