HK1223039A1 - 用於治療 陽性癌症的製劑和方法 - Google Patents

用於治療 陽性癌症的製劑和方法

Info

Publication number
HK1223039A1
HK1223039A1 HK16111415.6A HK16111415A HK1223039A1 HK 1223039 A1 HK1223039 A1 HK 1223039A1 HK 16111415 A HK16111415 A HK 16111415A HK 1223039 A1 HK1223039 A1 HK 1223039A1
Authority
HK
Hong Kong
Prior art keywords
preparations
treating
methods
positive cancer
cancer
Prior art date
Application number
HK16111415.6A
Other languages
English (en)
Inventor
Hans Loibner
Oliver Mutschlechner
Ruth Ladenstein
Isabel Klier
Original Assignee
Apeiron Biologics Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CA2834000A external-priority patent/CA2834000A1/en
Priority claimed from EP13193953.0A external-priority patent/EP2875827A1/en
Priority claimed from US14/182,776 external-priority patent/US10294305B2/en
Application filed by Apeiron Biologics Ag filed Critical Apeiron Biologics Ag
Publication of HK1223039A1 publication Critical patent/HK1223039A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3076—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties
    • C07K16/3084—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells against structure-related tumour-associated moieties against tumour-associated gangliosides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/58—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation
    • A61K2039/585—Medicinal preparations containing antigens or antibodies raising an immune response against a target which is not the antigen used for immunisation wherein the target is cancer
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/734—Complement-dependent cytotoxicity [CDC]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Oncology (AREA)
  • Biomedical Technology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
HK16111415.6A 2013-11-21 2016-09-29 用於治療 陽性癌症的製劑和方法 HK1223039A1 (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201314086696A 2013-11-21 2013-11-21
CA2834000A CA2834000A1 (en) 2013-11-21 2013-11-21 Method for treating a gd2 positive cancer
EP13193953.0A EP2875827A1 (en) 2013-11-21 2013-11-21 Preparations and methods for treating a GD2 positive cancer
US14/182,776 US10294305B2 (en) 2012-06-18 2014-02-18 Method for treating a GD2 positive cancer
PCT/EP2014/075315 WO2015075194A1 (en) 2013-11-21 2014-11-21 Preparations and methods for treating a gd2 positive cancer

Publications (1)

Publication Number Publication Date
HK1223039A1 true HK1223039A1 (zh) 2017-07-21

Family

ID=53179006

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16111415.6A HK1223039A1 (zh) 2013-11-21 2016-09-29 用於治療 陽性癌症的製劑和方法

Country Status (19)

Country Link
US (3) US10995147B2 (zh)
EP (2) EP3071220B1 (zh)
JP (2) JP6693873B2 (zh)
AU (2) AU2014351796B2 (zh)
CA (1) CA2930285A1 (zh)
CY (1) CY1122508T1 (zh)
DK (1) DK3071220T3 (zh)
EA (1) EA201691055A1 (zh)
ES (1) ES2768649T3 (zh)
HK (1) HK1223039A1 (zh)
HR (1) HRP20200128T1 (zh)
HU (1) HUE047920T2 (zh)
LT (1) LT3071220T (zh)
NZ (1) NZ720273A (zh)
PL (1) PL3071220T3 (zh)
PT (1) PT3071220T (zh)
RS (1) RS59817B1 (zh)
SI (1) SI3071220T1 (zh)
WO (1) WO2015075194A1 (zh)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013189516A1 (en) 2012-06-18 2013-12-27 Apeiron Biologics Ag Method for treating a gd2 positive cancer
US9840566B2 (en) 2013-11-21 2017-12-12 Apeiron Biologics Ag Preparations and methods for treating a GD2 positive cancer
PT3071220T (pt) 2013-11-21 2020-02-03 Apeiron Biologics Ag Preparações para tratamento de um cancro positivo para gd2
RU2663104C1 (ru) * 2017-07-13 2018-08-01 Общество с ограниченной ответственностью "Реал Таргет" Получение пегилированных фрагментов gd2-специфичных антител, индуцирующих прямую клеточную гибель gd2-позитивных опухолевых клеток, и их применение в терапии gd2-позитивных опухолей
AU2018336017B2 (en) 2017-09-21 2021-06-24 Tigatx, Inc. Anti-GD2 antibody for the treatment of neuroblastoma
EP4175988A1 (en) * 2020-07-06 2023-05-10 EUSA Pharma (UK) Limited Method for treating a gd2-positive cancer

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4863713A (en) 1986-06-23 1989-09-05 The Board Of Trustees Of Leland Stanford Jr. Univ. Method and system for administering therapeutic and diagnostic agents
WO2002072636A2 (en) 2000-12-28 2002-09-19 Altus Biologics Inc. Crystals of whole antibodies and fragments thereof and methods for making and using them
US7455833B2 (en) 2002-07-15 2008-11-25 Board Of Regents, The University Of Texas System Methods and compositions for treating viral infections using antibodies and immunoconjugates to aminophospholipids
ATE471946T1 (de) 2002-12-17 2010-07-15 Merck Patent Gmbh Humanisierter antikörper (h14.18) des maus antikörpers 14.18, der gd2 bindet und seine fusion mit il-2
ES2330860T3 (es) 2004-01-22 2009-12-16 Merck Patent Gmbh Anticuerpos anticancerosos con fijacion del complemento reducida.
US7807409B2 (en) 2005-10-21 2010-10-05 Roche Palo Alto Llc Method for the recombinant expression of a polypeptide
EP1916257A1 (en) 2006-10-27 2008-04-30 Charite-Universitätsmedizin Berlin GD2 peptide mimotopes for anticancer vaccination
TWI466684B (zh) 2008-06-30 2015-01-01 Morphotek Inc 抗ｇｄ２抗體及其相關方法及用途
AU2011268110B2 (en) 2010-06-19 2016-05-19 Memorial Sloan-Kettering Cancer Center Anti-GD2 antibodies
JP5623999B2 (ja) 2010-08-31 2014-11-12 パナソニック株式会社 電子装置
US10344050B2 (en) 2011-10-27 2019-07-09 Genmab A/S Production of heterodimeric proteins
EP2861251A1 (en) 2012-06-18 2015-04-22 Apeiron Biologics AG Method for treating a gd2 positive cancer
WO2013189516A1 (en) 2012-06-18 2013-12-27 Apeiron Biologics Ag Method for treating a gd2 positive cancer
PT3071220T (pt) 2013-11-21 2020-02-03 Apeiron Biologics Ag Preparações para tratamento de um cancro positivo para gd2
US9840566B2 (en) 2013-11-21 2017-12-12 Apeiron Biologics Ag Preparations and methods for treating a GD2 positive cancer

Also Published As

Publication number Publication date
US20210221909A1 (en) 2021-07-22
HRP20200128T1 (hr) 2020-05-15
US20200332021A1 (en) 2020-10-22
AU2014351796A2 (en) 2016-08-11
EP3071220A1 (en) 2016-09-28
EA201691055A1 (ru) 2016-11-30
EP3071220B1 (en) 2019-12-25
AU2014351796A1 (en) 2016-05-26
DK3071220T3 (da) 2020-02-10
RS59817B1 (sr) 2020-02-28
JP2016539122A (ja) 2016-12-15
HUE047920T2 (hu) 2020-05-28
PT3071220T (pt) 2020-02-03
LT3071220T (lt) 2020-02-25
US11492412B2 (en) 2022-11-08
EP3620173A1 (en) 2020-03-11
CA2930285A1 (en) 2015-05-28
CY1122508T1 (el) 2021-05-05
ES2768649T3 (es) 2020-06-23
JP6693873B2 (ja) 2020-05-13
US20240158530A1 (en) 2024-05-16
JP2019218359A (ja) 2019-12-26
AU2020203346A1 (en) 2020-06-11
JP7139293B2 (ja) 2022-09-20
SI3071220T1 (sl) 2020-03-31
US10995147B2 (en) 2021-05-04
NZ720273A (en) 2022-02-25
WO2015075194A1 (en) 2015-05-28
AU2014351796B2 (en) 2020-02-27
PL3071220T3 (pl) 2020-05-18

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