HK1222846A1 - 取代的苄基吡唑 - Google Patents

取代的苄基吡唑

Info

Publication number
HK1222846A1
HK1222846A1 HK16110960.7A HK16110960A HK1222846A1 HK 1222846 A1 HK1222846 A1 HK 1222846A1 HK 16110960 A HK16110960 A HK 16110960A HK 1222846 A1 HK1222846 A1 HK 1222846A1
Authority
HK
Hong Kong
Prior art keywords
benzylpyrazoles
substituted
substituted benzylpyrazoles
Prior art date
Application number
HK16110960.7A
Other languages
English (en)
Inventor
Marion Hitchcock
Anne Mengel
Hans Briem
Ulrich Lcking
Gerhard Siemeister
Wilhelm Bone
Jens Schrder
Michaela Bairlein
Ursula Mnning
Michael Brning
Original Assignee
Bayer Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Pharma AG filed Critical Bayer Pharma AG
Publication of HK1222846A1 publication Critical patent/HK1222846A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
HK16110960.7A 2013-06-21 2016-09-19 取代的苄基吡唑 HK1222846A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP13173278 2013-06-21
PCT/EP2014/062688 WO2014202583A1 (en) 2013-06-21 2014-06-17 Substituted benzylpyrazoles

Publications (1)

Publication Number Publication Date
HK1222846A1 true HK1222846A1 (zh) 2017-07-14

Family

ID=48651936

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16110960.7A HK1222846A1 (zh) 2013-06-21 2016-09-19 取代的苄基吡唑

Country Status (7)

Country Link
US (1) US20160151370A1 (zh)
EP (1) EP3010902A1 (zh)
JP (1) JP2016526540A (zh)
CN (1) CN105452236A (zh)
CA (1) CA2916097A1 (zh)
HK (1) HK1222846A1 (zh)
WO (1) WO2014202583A1 (zh)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA111754C2 (uk) 2011-10-06 2016-06-10 Байєр Фарма Акцієнгезелльшафт Заміщені бензиліндазоли для застосування як інгібіторів bub1-кінази для лікування гіперпроліферативних захворювань
WO2013092512A1 (en) 2011-12-21 2013-06-27 Bayer Intellectual Property Gmbh Substituted benzylpyrazoles
JP2016514719A (ja) * 2013-03-21 2016-05-23 バイエル ファーマ アクチエンゲゼルシャフト ヘテロアリール置換インダゾール
CN105408324A (zh) 2013-06-21 2016-03-16 拜耳制药股份公司 取代的苄基吡唑
US9745285B2 (en) 2013-06-21 2017-08-29 Bayer Pharma Aktiengesellschaft Heteroaryl substituted pyrazoles
CA2928998A1 (en) 2013-10-30 2015-05-07 Bayer Pharma Aktiengesellschaft Heteroaryl substituted pyrazoles
JP6545199B2 (ja) 2014-06-17 2019-07-17 バイエル ファーマ アクチエンゲゼルシャフト ３−アミノ−１，５，６，７−テトラヒドロ−４ｈ−インドール−４−オン類
BR112017005444A2 (pt) 2014-09-19 2018-04-24 Bayer Pharma AG indazoles substituídos por benzil como inibidores bub1.
CU20170094A7 (es) 2015-01-28 2017-12-08 Bayer Pharma AG Derivados de 4h-pirrol[3,2-c]piridin-4-0na
JP2018522847A (ja) 2015-06-17 2018-08-16 バイエル ファーマ アクチエンゲゼルシャフト ３−アミノ−１，５，６，７−テトラヒドロ−４ｈ−インドール−４−オン類
WO2017148995A1 (en) 2016-03-04 2017-09-08 Bayer Pharma Aktiengesellschaft 1-(pyrimidin-2-yl)-1h-indazoles having bub1 kinase inhibiting activity
WO2017157991A1 (en) 2016-03-18 2017-09-21 Bayer Pharma Aktiengesellschaft 1-alkyl-pyrazoles and -indazoles as bub1 inhibitors for the treatment of hyperproliferative diseases
WO2017157992A1 (en) 2016-03-18 2017-09-21 Bayer Pharma Aktiengesellschaft Annulated pyrazoles as bub1 kinase inhibitors for treating proliferative disorders
WO2018122168A1 (en) 2016-12-29 2018-07-05 Bayer Pharma Aktiengesellschaft Combinations of bub1 kinase and parp inhibitors
WO2018158175A1 (en) 2017-02-28 2018-09-07 Bayer Pharma Aktiengesellschaft Combination of bub1 inhibitors
WO2018206547A1 (en) 2017-05-12 2018-11-15 Bayer Pharma Aktiengesellschaft Combination of bub1 and atr inhibitors
WO2018215282A1 (en) 2017-05-26 2018-11-29 Bayer Pharma Aktiengesellschaft Combination of bub1 and pi3k inhibitors
WO2018234488A1 (en) 2017-06-23 2018-12-27 Basf Se SUBSTITUTED CYCLOPROPYL DERIVATIVES
IL301532A (en) 2020-09-23 2023-05-01 Scorpion Therapeutics Inc History Pyrrolo[2,3-C]pyridin-4-one is useful in cancer treatment
WO2022072634A1 (en) 2020-09-30 2022-04-07 Scorpion Therapeutics, Inc. Bicyclic compounds for use in the treatment cancer
WO2022072645A2 (en) 2020-09-30 2022-04-07 Scorpion Therapeutics, Inc. Methods for treating cancer
KR20230107419A (ko) 2020-10-09 2023-07-14 스코르피온 테라퓨틱스, 인코퍼레이티드 암 치료 방법
WO2022094271A1 (en) 2020-10-30 2022-05-05 Scorpion Therapeutics, Inc. Methods for treating cancer
WO2022098992A1 (en) 2020-11-05 2022-05-12 Scorpion Therapeutics, Inc. Use of macrocyclic compounds in methods of treating cancer
WO2022197913A1 (en) 2021-03-18 2022-09-22 Scorpion Therapeutics, Inc. Bicyclic derivatives which can be used to treat cancer
WO2023173083A1 (en) 2022-03-11 2023-09-14 Scorpion Therapeutics, Inc. Tetrahydroindole derivatives as egfr and/or her2 inhibtors useful for the treatment of cancer

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7863282B2 (en) * 2003-03-14 2011-01-04 Vertex Pharmaceuticals Incorporated Compositions useful as inhibitors of protein kinases
DE102005062742A1 (de) * 2005-12-22 2007-06-28 Bayer Schering Pharma Ag Sulfoximin substituierte Pyrimidine, Verfahren zu deren Herstellung und ihre Verwendung als Arzneimittel
WO2008141843A1 (en) * 2007-05-24 2008-11-27 Bayer Schering Pharma Aktiengesellschaft Novel sulphoximine-substituted quinazoline and quinazoline derivatives as kinase inhibitors
DE102010014426A1 (de) * 2010-04-01 2011-10-06 Bayer Schering Pharma Aktiengesellschaft Verwendung neuer pan-CDK-Inhibitoren zur Behandlung von Tumoren
ES2588102T3 (es) * 2011-09-16 2016-10-28 Bayer Intellectual Property Gmbh Derivados de 5-fluoro-pirimidina disustituidos que contienen un grupo sulfoximina
CA2849345A1 (en) * 2011-09-23 2013-03-28 Bayer Intellectual Property Gmbh Substituted imidazopyridazines
UA111754C2 (uk) * 2011-10-06 2016-06-10 Байєр Фарма Акцієнгезелльшафт Заміщені бензиліндазоли для застосування як інгібіторів bub1-кінази для лікування гіперпроліферативних захворювань
WO2013092512A1 (en) * 2011-12-21 2013-06-27 Bayer Intellectual Property Gmbh Substituted benzylpyrazoles
EP3010911A1 (en) * 2013-06-21 2016-04-27 Bayer Pharma Aktiengesellschaft Heteroaryl substituted pyrazoles

Also Published As

Publication number Publication date
CA2916097A1 (en) 2014-12-24
CN105452236A (zh) 2016-03-30
EP3010902A1 (en) 2016-04-27
US20160151370A1 (en) 2016-06-02
WO2014202583A1 (en) 2014-12-24
JP2016526540A (ja) 2016-09-05

Similar Documents

Publication Publication Date Title
HK1222846A1 (zh) 取代的苄基吡唑
HK1221717A1 (zh) 取代的苄基吡唑
DK3077519T3 (en) Cmv-vacciner
HRP20171890T1 (hr) Supstituirani imidazopiridazini
HK1223362A1 (zh) 取代的吡唑並吡啶胺
HK1220972A1 (zh) 取代的噻唑並嘧啶
IL246271A0 (en) Converted piperidinyl-tetrahydroquinolines
DK3056208T3 (en) Immunpotentiator
DK2979701T3 (en) Antitumormiddel indbefattende irinotecanhydrochloridhydrat
AU353644S (en) Stamphousing
DK2989854T3 (en) Strømstyret opvarmningssystem
AU4899P (en) Herbie53 Iresine herbstii
AU4953P (en) Flogazora Gazania rigens
AU4977P (en) Harrosy Gaura lindheimeri
AU353326S (en) Kettlebell
AU353329S (en) Kettlebell
AU353328S (en) Kettlebell
AU353330S (en) Kettlebell
AU353325S (en) Kettlebell
AU353331S (en) Kettlebell
AU353327S (en) Kettlebell
AP00812S1 (en) Stumbelbloc
AU2013231V (en) Bonsca7200 Scaevola aemula
AU353341S (en) Playsuit
AU354283S (en) Playsuit