HK1221263A1 - 唾液酸化的定量控制 - Google Patents

唾液酸化的定量控制

Info

Publication number
HK1221263A1
HK1221263A1 HK16109333.9A HK16109333A HK1221263A1 HK 1221263 A1 HK1221263 A1 HK 1221263A1 HK 16109333 A HK16109333 A HK 16109333A HK 1221263 A1 HK1221263 A1 HK 1221263A1
Authority
HK
Hong Kong
Prior art keywords
sialylation
quantitative control
quantitative
control
Prior art date
Application number
HK16109333.9A
Other languages
English (en)
Inventor
Alfred Engel
Michael Greif
Christine Jung
Sebastian Malik
Rainer Mueller
Harald Sobek
Bernhard Suppmann
Marco Thomann
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of HK1221263A1 publication Critical patent/HK1221263A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/18—Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1081—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/02—Monosaccharides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/005—Glycopeptides, glycoproteins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
HK16109333.9A 2013-05-29 2016-08-05 唾液酸化的定量控制 HK1221263A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP13169714 2013-05-29
EP13175390 2013-07-05
PCT/EP2014/060101 WO2014191240A1 (en) 2013-05-29 2014-05-16 Quantitative control of sialylation

Publications (1)

Publication Number Publication Date
HK1221263A1 true HK1221263A1 (zh) 2017-05-26

Family

ID=50736087

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16109333.9A HK1221263A1 (zh) 2013-05-29 2016-08-05 唾液酸化的定量控制

Country Status (7)

Country Link
US (1) US9809835B2 (zh)
EP (1) EP3004368B1 (zh)
JP (1) JP6594860B2 (zh)
CN (1) CN105324487B (zh)
CA (1) CA2908407C (zh)
HK (1) HK1221263A1 (zh)
WO (1) WO2014191240A1 (zh)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR095196A1 (es) 2013-03-15 2015-09-30 Regeneron Pharma Medio de cultivo celular libre de suero
EP2991666B1 (en) * 2013-05-02 2020-03-25 Momenta Pharmaceuticals, Inc. Sialylated glycoproteins
EP2996772B1 (en) 2013-05-13 2018-12-19 Momenta Pharmaceuticals, Inc. Methods for the treatment of neurodegeneration
EP3058084A4 (en) 2013-10-16 2017-07-05 Momenta Pharmaceuticals, Inc. Sialylated glycoproteins
EP3237608B1 (en) * 2014-12-22 2019-10-09 F. Hoffmann-La Roche AG Cmp-dependent sialidase activity
EP3037527A1 (en) * 2014-12-22 2016-06-29 F. Hoffmann-La Roche AG Sialyltransferase without CMP-dependent sialidase activity
TW202330904A (zh) 2015-08-04 2023-08-01 美商再生元醫藥公司 補充牛磺酸之細胞培養基及用法
CN110914293A (zh) * 2017-07-06 2020-03-24 里珍纳龙药品有限公司 用于制备糖蛋白的细胞培养工艺
US20220251619A1 (en) * 2019-03-29 2022-08-11 Agency For Science, Technology And Research Method of Sialylating a Protein
SG11202110942SA (en) * 2019-04-18 2021-11-29 Janssen Biotech Inc Sialylated glycoproteins

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5032519A (en) 1989-10-24 1991-07-16 The Regents Of The Univ. Of California Method for producing secretable glycosyltransferases and other Golgi processing enzymes
DE10258400A1 (de) * 2002-12-13 2004-06-24 N.V. Nutricia Trans-Sialidasen aus Trypanosoma congolense
AR045614A1 (es) 2003-09-10 2005-11-02 Hoffmann La Roche Anticuerpos contra el recepctor de la interleuquina- 1 y los usos de los mismos
US8431355B2 (en) * 2004-02-04 2013-04-30 Universite De Provence Aix-Marseille 1 Process for screening glycoform-specific antibodies
KR100805505B1 (ko) 2004-02-16 2008-02-20 미츠비시 레이온 가부시키가이샤 수지용 개질제 및 이것을 이용한 수지 조성물, 및 성형품
ES2543685T3 (es) * 2005-06-30 2015-08-21 Janssen Biotech, Inc. Métodos y composiciones con actividad terapéutica mejorada
CA2637389A1 (en) * 2006-01-18 2007-07-26 Chugai Seiyaku Kabushiki Kaisha Method of removing sialic acid and method for producing asialoerythropoietin
WO2007135194A2 (en) 2006-05-24 2007-11-29 Universite De Provence (Aix Marseille I) Preparation and uses of gene sequences encoding chimerical glycosyltransferases with optimized glycosylation activity
JP2008278761A (ja) 2007-05-08 2008-11-20 Tokai Univ 新規β−ガラクトシドα２，６−シアル酸転移酵素
CA2765237A1 (en) * 2009-06-12 2010-12-16 Japan Tobacco Inc. Novel protein and gene that codes therefor
US9187552B2 (en) * 2010-05-27 2015-11-17 Merck Sharp & Dohme Corp. Method for preparing antibodies having improved properties
AR085302A1 (es) * 2011-02-24 2013-09-18 Sanofi Sa Metodo de produccion de anticuerpos sialilados
SG2014012470A (en) * 2011-10-05 2014-06-27 Hoffmann La Roche Process for antibody g1 glycoform production

Also Published As

Publication number Publication date
EP3004368B1 (en) 2019-09-18
EP3004368A1 (en) 2016-04-13
CA2908407C (en) 2022-06-14
US20160076068A1 (en) 2016-03-17
WO2014191240A1 (en) 2014-12-04
US9809835B2 (en) 2017-11-07
CA2908407A1 (en) 2014-12-04
CN105324487A (zh) 2016-02-10
CN105324487B (zh) 2020-01-17
JP2016520315A (ja) 2016-07-14
JP6594860B2 (ja) 2019-10-23

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