HK1220691A1 - 用作卵泡刺激素受體調節劑的咪唑化合物及其用途 - Google Patents
用作卵泡刺激素受體調節劑的咪唑化合物及其用途Info
- Publication number
- HK1220691A1 HK1220691A1 HK16108822.9A HK16108822A HK1220691A1 HK 1220691 A1 HK1220691 A1 HK 1220691A1 HK 16108822 A HK16108822 A HK 16108822A HK 1220691 A1 HK1220691 A1 HK 1220691A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- fshr
- modulators
- imidazole compounds
- imidazole
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/12—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains three hetero rings
- C07D493/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/14—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361838502P | 2013-06-24 | 2013-06-24 | |
| US201361898611P | 2013-11-01 | 2013-11-01 | |
| PCT/US2014/043835 WO2014209978A1 (en) | 2013-06-24 | 2014-06-24 | Imidazole compounds as modulators of fshr and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1220691A1 true HK1220691A1 (zh) | 2017-05-12 |
Family
ID=51177211
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK16108822.9A HK1220691A1 (zh) | 2013-06-24 | 2016-07-22 | 用作卵泡刺激素受體調節劑的咪唑化合物及其用途 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US10138233B2 (zh) |
| EP (1) | EP3013823B1 (zh) |
| JP (1) | JP6523267B2 (zh) |
| CN (1) | CN105658650B (zh) |
| AU (1) | AU2014302710B2 (zh) |
| CA (1) | CA2912918C (zh) |
| ES (1) | ES2657979T3 (zh) |
| HK (1) | HK1220691A1 (zh) |
| IL (1) | IL243223B (zh) |
| WO (1) | WO2014209978A1 (zh) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT3129374T (pt) | 2014-04-07 | 2019-03-25 | Netherlands Translational Res Center B V | (5,6-dihidro)pirimido[4,5-e] indolizinas |
| WO2015196335A1 (en) | 2014-06-23 | 2015-12-30 | Tocopherx, Inc. | Pyrazole compounds as modulators of fshr and uses thereof |
| CN106177912B (zh) * | 2016-07-18 | 2019-06-18 | 暨南大学 | Ctrp3蛋白的应用 |
| CN114644641B (zh) * | 2020-12-17 | 2023-04-11 | 中国科学院广州生物医药与健康研究院 | 基于螺旋骨架的手性二酚及其制备方法和应用 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3512110B2 (ja) * | 1992-02-13 | 2004-03-29 | ファルマシア・アンド・アップジョン・カンパニー | ベンゾジアゼピン受容体結合剤として有用な４−オキソ−および４Ｈ−イミダゾ（５，１−ｃ）（１，４）ベンゾオキサジン類 |
| DE19805117A1 (de) | 1998-02-09 | 1999-08-12 | Bayer Ag | Neue Oxazolidinone mit azolhaltigen Tricyclen |
| ATE329911T1 (de) | 1998-08-07 | 2006-07-15 | Applied Research Systems | Fsh mimetika zur behandlung von infertilität |
| JP4409680B2 (ja) * | 1999-10-18 | 2010-02-03 | 株式会社ヤクルト本社 | 三環性縮合イミダゾール誘導体 |
| WO2002009706A1 (en) | 2000-07-27 | 2002-02-07 | Smithkline Beecham Corporation | Agonists of follicle stimulating hormone activity |
| TWI329105B (en) * | 2002-02-01 | 2010-08-21 | Rigel Pharmaceuticals Inc | 2,4-pyrimidinediamine compounds and their uses |
| PE20060653A1 (es) * | 2004-08-31 | 2006-09-27 | Glaxo Group Ltd | Derivados triciclicos condensados como moduladores del receptor 5-ht1 |
| DE602007012473D1 (de) * | 2006-12-14 | 2011-03-24 | Vertex Pharma | Als proteinkinaseinhibitoren geeignete verbindungen |
| WO2010025073A1 (en) * | 2008-08-28 | 2010-03-04 | Takeda Pharmaceutical Company Limited | Dihydroimidazo [ 1, 5-f] pteridines as polo-like kinase inhibitors |
| EP2361910A4 (en) | 2008-10-29 | 2012-08-01 | Taisho Pharmaceutical Co Ltd | CONNECTION WITH TAFIA-INHIBITOR EFFECT |
| TWI461426B (zh) * | 2009-05-27 | 2014-11-21 | Merck Sharp & Dohme | （二氫）咪唑並異〔５，１－ａ〕喹啉類 |
| WO2011151361A1 (en) * | 2010-06-03 | 2011-12-08 | Glaxo Group Limited | Novel compounds |
| EP2763986B1 (en) * | 2011-09-22 | 2017-06-07 | Merck Sharp & Dohme B.V. | Fsh receptor antagonists |
-
2014
- 2014-06-24 CN CN201480046774.6A patent/CN105658650B/zh active Active
- 2014-06-24 ES ES14739012.4T patent/ES2657979T3/es active Active
- 2014-06-24 EP EP14739012.4A patent/EP3013823B1/en active Active
- 2014-06-24 WO PCT/US2014/043835 patent/WO2014209978A1/en active Application Filing
- 2014-06-24 JP JP2016521899A patent/JP6523267B2/ja active Active
- 2014-06-24 AU AU2014302710A patent/AU2014302710B2/en active Active
- 2014-06-24 US US14/900,215 patent/US10138233B2/en active Active
- 2014-06-24 CA CA2912918A patent/CA2912918C/en active Active
-
2015
- 2015-12-20 IL IL243223A patent/IL243223B/en active IP Right Grant
-
2016
- 2016-07-22 HK HK16108822.9A patent/HK1220691A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2657979T3 (es) | 2018-03-07 |
| AU2014302710B2 (en) | 2018-10-04 |
| EP3013823A1 (en) | 2016-05-04 |
| US10138233B2 (en) | 2018-11-27 |
| IL243223A0 (en) | 2016-02-29 |
| JP2016523864A (ja) | 2016-08-12 |
| EP3013823B1 (en) | 2017-11-01 |
| JP6523267B2 (ja) | 2019-05-29 |
| IL243223B (en) | 2019-07-31 |
| AU2014302710A1 (en) | 2015-12-03 |
| CN105658650A (zh) | 2016-06-08 |
| CN105658650B (zh) | 2019-01-08 |
| WO2014209978A1 (en) | 2014-12-31 |
| CA2912918C (en) | 2021-07-27 |
| US20160152609A1 (en) | 2016-06-02 |
| CA2912918A1 (en) | 2014-12-31 |
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