HK1220176A1 - 用於 -二甲基- -二氫- -喹喔啉- -酮衍生物的生產方法及用於所述生產方法的中間體 - Google Patents
用於 -二甲基- -二氫- -喹喔啉- -酮衍生物的生產方法及用於所述生產方法的中間體Info
- Publication number
- HK1220176A1 HK1220176A1 HK16108118.2A HK16108118A HK1220176A1 HK 1220176 A1 HK1220176 A1 HK 1220176A1 HK 16108118 A HK16108118 A HK 16108118A HK 1220176 A1 HK1220176 A1 HK 1220176A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- production method
- quinoxaline
- dihydro
- dimethyl
- derivative
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
- C07D241/40—Benzopyrazines
- C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/52—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
- C07C229/54—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring
- C07C229/60—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton with amino and carboxyl groups bound to carbon atoms of the same non-condensed six-membered aromatic ring with amino and carboxyl groups bound in meta- or para- positions
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2013166643 | 2013-08-09 | ||
| PCT/JP2014/071053 WO2015020204A1 (ja) | 2013-08-09 | 2014-08-08 | ３，３－ジメチル－３，４－ジヒドロ－１ｈ－キノキサリン－２－オン誘導体の製造方法およびその製造方法の中間体 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1220176A1 true HK1220176A1 (zh) | 2017-04-28 |
Family
ID=52461528
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK16108118.2A HK1220176A1 (zh) | 2013-08-09 | 2016-07-12 | 用於 -二甲基- -二氫- -喹喔啉- -酮衍生物的生產方法及用於所述生產方法的中間體 |
| HK16108543.7A HK1220462A1 (zh) | 2013-08-09 | 2016-07-19 | －二甲基－ －二氫－ －喹喔啉－ －酮衍生物的製造方法及該製造方法的中間體 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK16108543.7A HK1220462A1 (zh) | 2013-08-09 | 2016-07-19 | －二甲基－ －二氫－ －喹喔啉－ －酮衍生物的製造方法及該製造方法的中間體 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US9676703B2 (zh) |
| EP (1) | EP3031802A4 (zh) |
| JP (1) | JP2015057381A (zh) |
| KR (1) | KR20160040298A (zh) |
| CN (1) | CN105473557A (zh) |
| CA (1) | CA2920353A1 (zh) |
| HK (2) | HK1220176A1 (zh) |
| RU (1) | RU2016107848A (zh) |
| TW (1) | TW201536760A (zh) |
| WO (1) | WO2015020204A1 (zh) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20200121652A1 (en) | 2017-06-16 | 2020-04-23 | The Doshisha | Compounds having caspase inhibitory activity, pharmaceutical agent containing said compounds and for treating or preventing corneal endothelial symptoms, disorders, or diseases, and application of said pharmaceutical agent |
| AU2018283250B2 (en) | 2017-06-16 | 2022-09-01 | The Doshisha | mTOR-inhibitor-containing medicine for treating or preventing ophthalmic symptoms, disorders, or diseases, and application thereof |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE59209965D1 (de) | 1991-04-15 | 2002-10-17 | Aventis Pharma Gmbh | Chinoxaline, Verfahren zu ihrer Herstellung und ihre Verwendung |
| US6369057B1 (en) | 1991-04-15 | 2002-04-09 | Aventis Pharma Deutschland Gmbh | Quinoxalines, processes for their preparation and their use |
| WO2004050659A1 (en) * | 2002-11-27 | 2004-06-17 | Eli Lilly And Company | Novel compounds as pharmaceutical agents |
| US7235662B2 (en) | 2003-06-11 | 2007-06-26 | Bristol-Myers Squibb Company | Modulators of the glucocorticoid receptor and method |
| US7256294B2 (en) | 2005-05-25 | 2007-08-14 | Theravance, Inc. | Crystalline form of a benzimidazole-carboxamide medicinal compound |
| MY147756A (en) | 2005-05-25 | 2013-01-15 | Theravance Inc | Benzimidazole-carboxamide compounds as 5-ht4 receptor agonists |
| WO2007041077A2 (en) * | 2005-09-30 | 2007-04-12 | Janssen Pharmaceutica N.V. | Heterocyclic amide derivatives as rxr agonists for the treatment of dyslipidemia, hypercholesterolemia and diabetes |
| CA2643070C (en) | 2006-03-14 | 2016-01-26 | Santen Pharmaceutical Co., Ltd. | Novel 1,2,3,4-tetrahydroquinoxaline derivative having glucocorticoid receptor binding activity |
| BRPI1010649A2 (pt) | 2009-06-08 | 2016-06-07 | Gruenenthal Gmbh | benzimidazóis, benzotiazóis e benzoxazoles substituídos. |
-
2014
- 2014-08-08 JP JP2014162444A patent/JP2015057381A/ja active Pending
- 2014-08-08 RU RU2016107848A patent/RU2016107848A/ru not_active Application Discontinuation
- 2014-08-08 KR KR1020167006210A patent/KR20160040298A/ko not_active Application Discontinuation
- 2014-08-08 EP EP14834436.9A patent/EP3031802A4/en not_active Withdrawn
- 2014-08-08 CN CN201480044112.5A patent/CN105473557A/zh active Pending
- 2014-08-08 US US14/910,971 patent/US9676703B2/en not_active Expired - Fee Related
- 2014-08-08 WO PCT/JP2014/071053 patent/WO2015020204A1/ja active Application Filing
- 2014-08-08 TW TW103127194A patent/TW201536760A/zh unknown
- 2014-08-08 CA CA2920353A patent/CA2920353A1/en not_active Abandoned
-
2016
- 2016-07-12 HK HK16108118.2A patent/HK1220176A1/zh unknown
- 2016-07-19 HK HK16108543.7A patent/HK1220462A1/zh unknown
-
2017
- 2017-05-12 US US15/593,531 patent/US20170247342A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US9676703B2 (en) | 2017-06-13 |
| RU2016107848A (ru) | 2017-09-15 |
| EP3031802A4 (en) | 2017-07-12 |
| CN105473557A (zh) | 2016-04-06 |
| US20160200690A1 (en) | 2016-07-14 |
| HK1220462A1 (zh) | 2017-05-05 |
| RU2016107848A3 (zh) | 2018-05-31 |
| EP3031802A1 (en) | 2016-06-15 |
| WO2015020204A1 (ja) | 2015-02-12 |
| CA2920353A1 (en) | 2015-02-12 |
| KR20160040298A (ko) | 2016-04-12 |
| JP2015057381A (ja) | 2015-03-26 |
| TW201536760A (zh) | 2015-10-01 |
| US20170247342A1 (en) | 2017-08-31 |
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