HK1217968A1 - 用於hla的修饰的方法和组合物 - Google Patents

用於hla的修饰的方法和组合物 Download PDF

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Publication number
HK1217968A1
HK1217968A1 HK16105965.2A HK16105965A HK1217968A1 HK 1217968 A1 HK1217968 A1 HK 1217968A1 HK 16105965 A HK16105965 A HK 16105965A HK 1217968 A1 HK1217968 A1 HK 1217968A1
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HK
Hong Kong
Prior art keywords
hla
cell
cells
gene
protein
Prior art date
Application number
HK16105965.2A
Other languages
English (en)
Chinese (zh)
Inventor
‧格雷戈里
P‧D‧格雷戈里
‧庫珀
L‧J‧N‧库珀
‧托里開
H‧托里开
Original Assignee
桑格摩生物科学股份有限公司
得克萨斯州大学系统董事会
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by 桑格摩生物科学股份有限公司, 得克萨斯州大学系统董事会 filed Critical 桑格摩生物科学股份有限公司
Publication of HK1217968A1 publication Critical patent/HK1217968A1/zh

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0646—Natural killers cells [NK], NKT cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/15—Natural-killer [NK] cells; Natural-killer T [NKT] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/31—Chimeric antigen receptors [CAR]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A61K40/4202—Receptors, cell surface antigens or cell surface determinants
    • A61K40/421—Immunoglobulin superfamily
    • A61K40/4211—CD19 or B4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/50—Cellular immunotherapy characterised by the use of allogeneic cells

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Transplantation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Developmental Biology & Embryology (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
HK16105965.2A 2013-03-12 2014-03-12 用於hla的修饰的方法和组合物 HK1217968A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361777627P 2013-03-12 2013-03-12
US61/777,627 2013-03-12
PCT/US2014/024660 WO2014165177A1 (en) 2013-03-12 2014-03-12 Methods and compositions for modification of hla

Publications (1)

Publication Number Publication Date
HK1217968A1 true HK1217968A1 (zh) 2017-01-27

Family

ID=51659088

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16105965.2A HK1217968A1 (zh) 2013-03-12 2014-03-12 用於hla的修饰的方法和组合物

Country Status (9)

Country Link
US (3) US20150037304A1 (https=)
EP (1) EP2970886B1 (https=)
JP (1) JP6433480B2 (https=)
CN (1) CN105283539A (https=)
AU (3) AU2014248605B2 (https=)
CA (1) CA2904210C (https=)
HK (1) HK1217968A1 (https=)
IL (1) IL241112B (https=)
WO (1) WO2014165177A1 (https=)

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Also Published As

Publication number Publication date
US20150037304A1 (en) 2015-02-05
AU2014248605A1 (en) 2015-09-24
CN105283539A (zh) 2016-01-27
AU2014248605B2 (en) 2020-05-28
US20220202858A1 (en) 2022-06-30
EP2970886A1 (en) 2016-01-20
IL241112B (en) 2021-02-28
CA2904210A1 (en) 2014-10-09
US20170216358A1 (en) 2017-08-03
CA2904210C (en) 2022-07-19
JP2016513460A (ja) 2016-05-16
EP2970886A4 (en) 2016-08-17
AU2022211891A1 (en) 2022-09-01
IL241112A0 (en) 2015-11-30
JP6433480B2 (ja) 2018-12-05
AU2020203765A1 (en) 2020-06-25
EP2970886B1 (en) 2018-05-23
WO2014165177A1 (en) 2014-10-09

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