HK1212971A1 - 生產阿托伐他汀中間體的方法 - Google Patents

生產阿托伐他汀中間體的方法

Info

Publication number
HK1212971A1
HK1212971A1 HK16100775.3A HK16100775A HK1212971A1 HK 1212971 A1 HK1212971 A1 HK 1212971A1 HK 16100775 A HK16100775 A HK 16100775A HK 1212971 A1 HK1212971 A1 HK 1212971A1
Authority
HK
Hong Kong
Prior art keywords
produce atorvastatin
intermediates
atorvastatin intermediates
produce
atorvastatin
Prior art date
Application number
HK16100775.3A
Other languages
English (en)
Inventor
De Ben Lange
Dennis Heemskerk
Henricus Leonardus Marie Elsenberg
Original Assignee
Dsm Sinochem Pharm Nl Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm Sinochem Pharm Nl Bv filed Critical Dsm Sinochem Pharm Nl Bv
Publication of HK1212971A1 publication Critical patent/HK1212971A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HK16100775.3A 2012-09-17 2016-01-22 生產阿托伐他汀中間體的方法 HK1212971A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12184689 2012-09-17
PCT/EP2013/068886 WO2014041058A1 (en) 2012-09-17 2013-09-12 Process to produce atorvastatin intermediates

Publications (1)

Publication Number Publication Date
HK1212971A1 true HK1212971A1 (zh) 2016-06-24

Family

ID=46881006

Family Applications (1)

Application Number Title Priority Date Filing Date
HK16100775.3A HK1212971A1 (zh) 2012-09-17 2016-01-22 生產阿托伐他汀中間體的方法

Country Status (8)

Country Link
US (1) US20150259285A1 (zh)
EP (1) EP2895459A1 (zh)
CN (1) CN104619685A (zh)
HK (1) HK1212971A1 (zh)
IL (1) IL237335A0 (zh)
IN (1) IN2015DN01444A (zh)
MX (1) MX2015003311A (zh)
WO (1) WO2014041058A1 (zh)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008533128A (ja) * 2005-03-14 2008-08-21 ファイザー・サイエンス・アンド・テクノロジー・アイルランド・リミテッド Ｐａａｌ−Ｋｎｏｒｒ縮合を用いた、アトルバスタチン中間体の製造
HUE025861T2 (en) * 2010-09-09 2016-05-30 Dsm Sinochem Pharm Nl Bv Salts of 7-amino-3,5-dihydroxy-heptanoic acid esters

Also Published As

Publication number Publication date
IN2015DN01444A (zh) 2015-07-03
MX2015003311A (es) 2015-07-14
EP2895459A1 (en) 2015-07-22
IL237335A0 (en) 2015-04-30
CN104619685A (zh) 2015-05-13
US20150259285A1 (en) 2015-09-17
WO2014041058A1 (en) 2014-03-20

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