HK1209727A1 - 羧酸衍生物及其中間體的製備方法 - Google Patents

羧酸衍生物及其中間體的製備方法

Info

Publication number
HK1209727A1
HK1209727A1 HK15110339.2A HK15110339A HK1209727A1 HK 1209727 A1 HK1209727 A1 HK 1209727A1 HK 15110339 A HK15110339 A HK 15110339A HK 1209727 A1 HK1209727 A1 HK 1209727A1
Authority
HK
Hong Kong
Prior art keywords
intermediates
carboxylic acid
preparation process
acid derivatives
derivatives
Prior art date
Application number
HK15110339.2A
Other languages
English (en)
Inventor
Nicolas Tesson
Castao Montserrat Trilla
Original Assignee
Kern Pharma S L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kern Pharma S L filed Critical Kern Pharma S L
Publication of HK1209727A1 publication Critical patent/HK1209727A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/60—Three or more oxygen or sulfur atoms
    • C07D239/62—Barbituric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/41—Preparation of salts of carboxylic acids
    • C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/43—Separation; Purification; Stabilisation; Use of additives by change of the physical state, e.g. crystallisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C63/00—Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
    • C07C63/33—Polycyclic acids
    • C07C63/331—Polycyclic acids with all carboxyl groups bound to non-condensed rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/34—One oxygen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HK15110339.2A 2012-06-29 2015-10-21 羧酸衍生物及其中間體的製備方法 HK1209727A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12382259 2012-06-29
PCT/EP2013/063649 WO2014001511A1 (en) 2012-06-29 2013-06-28 Preparation process of carboxylic acid derivatives and intermediates thereof

Publications (1)

Publication Number Publication Date
HK1209727A1 true HK1209727A1 (zh) 2016-04-08

Family

ID=48700601

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15110339.2A HK1209727A1 (zh) 2012-06-29 2015-10-21 羧酸衍生物及其中間體的製備方法

Country Status (16)

Country Link
US (1) US9533960B2 (zh)
EP (1) EP2867214B1 (zh)
CA (1) CA2875942A1 (zh)
CY (1) CY1118185T1 (zh)
DK (1) DK2867214T3 (zh)
ES (1) ES2598855T3 (zh)
HK (1) HK1209727A1 (zh)
HR (1) HRP20161438T1 (zh)
HU (1) HUE029470T2 (zh)
LT (1) LT2867214T (zh)
PL (1) PL2867214T3 (zh)
PT (1) PT2867214T (zh)
RS (1) RS55345B1 (zh)
SI (1) SI2867214T1 (zh)
SM (1) SMT201600401B (zh)
WO (1) WO2014001511A1 (zh)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19533023B4 (de) 1994-10-14 2007-05-16 Basf Ag Neue Carbonsäurederivate, ihre Herstellung und Verwendung
DE19850301A1 (de) 1998-10-30 2000-05-04 Basf Ag Verfahren zur Racematspaltung von 2-Hydroxypropionsäuren
US8404840B2 (en) 2008-11-05 2013-03-26 Msn Laboratories Limited Process for the preparation of endothelin receptor antagonists
EP2451786B1 (en) 2009-07-10 2014-01-22 Cadila Healthcare Limited Improved process for the preparation of ambrisentan and novel intermediates thereof
US20130184490A1 (en) 2010-08-04 2013-07-18 Natco Pharma Limited Process to prepare s-2-hydroxy-3-methoxy-3,3-diphenyl propionic acid

Also Published As

Publication number Publication date
RS55345B1 (sr) 2017-03-31
CA2875942A1 (en) 2014-01-03
PL2867214T3 (pl) 2017-02-28
EP2867214B1 (en) 2016-08-10
SMT201600401B (it) 2017-01-10
HRP20161438T1 (hr) 2016-12-16
LT2867214T (lt) 2016-11-25
PT2867214T (pt) 2016-11-11
CY1118185T1 (el) 2017-06-28
US20150299140A1 (en) 2015-10-22
HUE029470T2 (en) 2017-02-28
SI2867214T1 (sl) 2017-01-31
US9533960B2 (en) 2017-01-03
WO2014001511A1 (en) 2014-01-03
DK2867214T3 (en) 2016-11-28
ES2598855T3 (es) 2017-01-30
EP2867214A1 (en) 2015-05-06

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20210627