HK1209433A1 - Boc and fmoc solid phase peptide synthesis boc fmoc - Google Patents

Boc and fmoc solid phase peptide synthesis boc fmoc

Info

Publication number
HK1209433A1
HK1209433A1 HK15110059.0A HK15110059A HK1209433A1 HK 1209433 A1 HK1209433 A1 HK 1209433A1 HK 15110059 A HK15110059 A HK 15110059A HK 1209433 A1 HK1209433 A1 HK 1209433A1
Authority
HK
Hong Kong
Prior art keywords
boc
fmoc
solid phase
peptide synthesis
phase peptide
Prior art date
Application number
HK15110059.0A
Other languages
English (en)
Chinese (zh)
Inventor
Catherine Fiona Dalton
John Stuart Eynon
Steven Allen Jackson
Gary Alexander Siwruk
Original Assignee
Ipsen Mfg Ireland Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ipsen Mfg Ireland Ltd filed Critical Ipsen Mfg Ireland Ltd
Publication of HK1209433A1 publication Critical patent/HK1209433A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/042—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers characterised by the nature of the carrier
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/003—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by transforming the C-terminal amino acid to amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
    • C07K1/063—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for alpha-amino functions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/08—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using activating agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/10—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using coupling agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/64—Relaxins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK15110059.0A 2006-11-21 2015-10-14 Boc and fmoc solid phase peptide synthesis boc fmoc HK1209433A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IE20060841A IE20060841A1 (en) 2006-11-21 2006-11-21 Boc and fmoc solid phase peptide synthesis

Publications (1)

Publication Number Publication Date
HK1209433A1 true HK1209433A1 (en) 2016-04-01

Family

ID=39430143

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15110059.0A HK1209433A1 (en) 2006-11-21 2015-10-14 Boc and fmoc solid phase peptide synthesis boc fmoc

Country Status (21)

Country Link
US (3) US8383770B2 (fr)
EP (1) EP2084176B1 (fr)
JP (3) JP5281581B2 (fr)
KR (1) KR101237561B1 (fr)
CN (2) CN101541824A (fr)
AU (1) AU2007323057B2 (fr)
BR (1) BRPI0718996B8 (fr)
CA (1) CA2670209C (fr)
DK (1) DK2084176T3 (fr)
ES (1) ES2682103T3 (fr)
HK (1) HK1209433A1 (fr)
HU (1) HUE038926T2 (fr)
IE (2) IE20060841A1 (fr)
IL (2) IL198451A0 (fr)
MX (1) MX2009005377A (fr)
NO (1) NO344798B1 (fr)
NZ (1) NZ577395A (fr)
PL (1) PL2084176T3 (fr)
PT (1) PT2084176T (fr)
RU (1) RU2439075C2 (fr)
WO (1) WO2008062391A2 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE480561T1 (de) 2004-10-19 2010-09-15 Lonza Ag Verfahren zur festphasen-peptidsynthese
IE20060841A1 (en) * 2006-11-21 2008-05-28 Ipsen Mfg Ireland Ltd Boc and fmoc solid phase peptide synthesis
CN101628929B (zh) * 2009-08-27 2014-09-17 中国人民解放军防化学院 一种固相合成侧链保护肽链的新方法
CN102286078A (zh) * 2011-07-13 2011-12-21 中国药科大学 一种多肽hm-3的制备方法
EP2664374A1 (fr) * 2012-05-15 2013-11-20 F. Hoffmann-La Roche AG Dérivés de dipeptide d'acide lysine-glutamique
CA3009065C (fr) 2015-12-21 2022-01-25 Texas Tech University System Systeme et procede de synthese de peptides gap en phase solution
WO2017212390A1 (fr) * 2016-06-06 2017-12-14 Emcure Pharmaceuticals Ltd, Procédé de préparation d'acétate de lanréotide
CN108059667B (zh) * 2018-02-10 2018-11-13 润辉生物技术（威海）有限公司 一种兰瑞肽的固相合成方法
CN108440654B (zh) * 2018-02-24 2020-09-04 暨南大学 一种抗菌活性环六肽Thermoactinoamide A的合成方法
JP2021531326A (ja) 2018-05-31 2021-11-18 ギャップ ペプチド エルエルシーGap Peptides Llc 液相ペプチド合成のための方法およびその保護戦略
WO2020159837A1 (fr) 2019-02-01 2020-08-06 Gap Peptides Llc Stratégie de synthèse pour groupe de protection gap
US12024537B2 (en) 2018-05-31 2024-07-02 Sederma Compositions and methods for chemical synthesis
KR20230175279A (ko) 2021-04-23 2023-12-29 쎄데르마 펩티드의 화학적 합성을 위한 조성물
CN118715234A (zh) * 2022-04-08 2024-09-27 中外制药株式会社 肽化合物的制造方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4411890A (en) * 1981-04-14 1983-10-25 Beckman Instruments, Inc. Synthetic peptides having pituitary growth hormone releasing activity
US4307083A (en) * 1978-10-16 1981-12-22 The Salk Institute For Biological Studies LRF Antagonists
GB8427651D0 (en) * 1984-11-01 1984-12-05 Beecham Group Plc Compounds
ATE452145T1 (de) * 2005-05-03 2010-01-15 Novetide Ltd Verfahren zur herstellung von peptidderivaten
IE20060841A1 (en) * 2006-11-21 2008-05-28 Ipsen Mfg Ireland Ltd Boc and fmoc solid phase peptide synthesis

Also Published As

Publication number Publication date
BRPI0718996B1 (pt) 2019-08-27
IE20060841A1 (en) 2008-05-28
DK2084176T3 (en) 2018-08-27
IES20070687A2 (en) 2008-05-14
US8383770B2 (en) 2013-02-26
BRPI0718996B8 (pt) 2021-05-25
JP2010510304A (ja) 2010-04-02
US9090654B2 (en) 2015-07-28
WO2008062391A2 (fr) 2008-05-29
JP5798149B2 (ja) 2015-10-21
EP2084176B1 (fr) 2018-05-30
RU2439075C2 (ru) 2012-01-10
JP6141367B2 (ja) 2017-06-07
EP2084176A2 (fr) 2009-08-05
CA2670209A1 (fr) 2008-05-29
WO2008062391A3 (fr) 2008-10-02
RU2009122664A (ru) 2010-12-27
JP2016000749A (ja) 2016-01-07
PL2084176T3 (pl) 2018-11-30
AU2007323057B2 (en) 2011-07-28
NZ577395A (en) 2011-10-28
ES2682103T3 (es) 2018-09-18
IL243230A0 (en) 2016-02-29
BRPI0718996A2 (pt) 2014-02-18
IL198451A0 (en) 2010-02-17
JP5281581B2 (ja) 2013-09-04
PT2084176T (pt) 2018-08-01
CN104530190A (zh) 2015-04-22
US20130338337A1 (en) 2013-12-19
NO344798B1 (no) 2020-05-04
NO20092247L (no) 2009-08-17
MX2009005377A (es) 2009-09-28
US20100160604A1 (en) 2010-06-24
AU2007323057A1 (en) 2008-05-29
KR20090100369A (ko) 2009-09-23
CN101541824A (zh) 2009-09-23
HUE038926T2 (hu) 2018-12-28
KR101237561B1 (ko) 2013-02-27
US20150284424A1 (en) 2015-10-08
CA2670209C (fr) 2012-04-10
JP2013163693A (ja) 2013-08-22

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