HK1207321A1 - Compositions and methods related to antibodies that neutralize coagulase activity during staphylococcus aureus disease - Google Patents

Compositions and methods related to antibodies that neutralize coagulase activity during staphylococcus aureus disease Download PDF

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Publication number
HK1207321A1
HK1207321A1 HK15108152.0A HK15108152A HK1207321A1 HK 1207321 A1 HK1207321 A1 HK 1207321A1 HK 15108152 A HK15108152 A HK 15108152A HK 1207321 A1 HK1207321 A1 HK 1207321A1
Authority
HK
Hong Kong
Prior art keywords
compositions
neutralize
antibodies
staphylococcus aureus
activity during
Prior art date
Application number
HK15108152.0A
Other languages
English (en)
Chinese (zh)
Inventor
Molly MCADOW
Carla EMOLO
Dominique M. Missiakas
Olaf Schneewind
Original Assignee
University Of Chicago
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University Of Chicago filed Critical University Of Chicago
Publication of HK1207321A1 publication Critical patent/HK1207321A1/xx

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
    • C07K16/1271—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Micrococcaceae (F), e.g. Staphylococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
HK15108152.0A 2012-04-26 2013-03-15 Compositions and methods related to antibodies that neutralize coagulase activity during staphylococcus aureus disease HK1207321A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261638797P 2012-04-26 2012-04-26
US61/638,797 2012-04-26
PCT/US2013/031927 WO2013162751A1 (en) 2012-04-26 2013-03-15 Compositions and methods related to antibodies that neutralize coagulase activity during staphylococcus aureus disease

Publications (1)

Publication Number Publication Date
HK1207321A1 true HK1207321A1 (en) 2016-01-29

Family

ID=49483735

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15108152.0A HK1207321A1 (en) 2012-04-26 2013-03-15 Compositions and methods related to antibodies that neutralize coagulase activity during staphylococcus aureus disease

Country Status (10)

Country Link
US (2) US9701738B2 (OSRAM)
EP (1) EP2841101B1 (OSRAM)
JP (2) JP6251730B2 (OSRAM)
CN (1) CN104703622B (OSRAM)
AU (1) AU2013252888B2 (OSRAM)
BR (1) BR112014026808A2 (OSRAM)
CA (1) CA2910320A1 (OSRAM)
HK (1) HK1207321A1 (OSRAM)
NZ (1) NZ702282A (OSRAM)
WO (1) WO2013162751A1 (OSRAM)

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CA2937054C (en) * 2014-01-24 2023-02-14 William R. Church Antibody specific to staphylococcus aureus, therapeutic method and detection method using same
JP7117244B2 (ja) * 2016-02-12 2022-08-12 ザ・ユニバーシティ・オブ・シカゴ 黄色ブドウ球菌疾患の間にコアグラーゼ活性を中和する抗体に関連した組成物および方法
KR20190020341A (ko) * 2016-06-28 2019-02-28 젠코어 인코포레이티드 소마토스타틴 수용체 2에 결합하는 이종이량체 항체
US10738338B2 (en) 2016-10-18 2020-08-11 The Research Foundation for the State University Method and composition for biocatalytic protein-oligonucleotide conjugation and protein-oligonucleotide conjugate
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Also Published As

Publication number Publication date
WO2013162751A1 (en) 2013-10-31
JP2018058871A (ja) 2018-04-12
CN104703622A (zh) 2015-06-10
AU2013252888A1 (en) 2014-12-11
JP6251730B2 (ja) 2017-12-20
US20170306004A1 (en) 2017-10-26
US20150368322A1 (en) 2015-12-24
NZ702282A (en) 2016-07-29
AU2013252888B2 (en) 2018-06-14
CA2910320A1 (en) 2013-10-31
EP2841101A4 (en) 2016-02-24
EP2841101A1 (en) 2015-03-04
CN104703622B (zh) 2017-05-24
BR112014026808A2 (pt) 2018-05-15
JP2015515492A (ja) 2015-05-28
EP2841101B1 (en) 2019-08-07
US9701738B2 (en) 2017-07-11

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