HK1204564A1 - Topical ophthalmological pharmaceutical composition containing axitinib - Google Patents

Topical ophthalmological pharmaceutical composition containing axitinib

Info

Publication number
HK1204564A1
HK1204564A1 HK15105108.1A HK15105108A HK1204564A1 HK 1204564 A1 HK1204564 A1 HK 1204564A1 HK 15105108 A HK15105108 A HK 15105108A HK 1204564 A1 HK1204564 A1 HK 1204564A1
Authority
HK
Hong Kong
Prior art keywords
pharmaceutical composition
composition containing
ophthalmological pharmaceutical
topical ophthalmological
containing axitinib
Prior art date
Application number
HK15105108.1A
Other languages
English (en)
Chinese (zh)
Inventor
Michael Bttger
Degenfeld Georges Von
Julia Freundlieb
Claudia Hirth-Dietrich
Joerg Keldenich
Jrgen Klar
Uwe Muenster
Andreas Ohm
Annett Richter
Bernd Riedl
Joachim Telser
Original Assignee
Bayer Healthcare Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP2012/062365 external-priority patent/WO2013000917A1/en
Application filed by Bayer Healthcare Llc filed Critical Bayer Healthcare Llc
Publication of HK1204564A1 publication Critical patent/HK1204564A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/12—Ophthalmic agents for cataracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
HK15105108.1A 2012-06-25 2015-05-29 Topical ophthalmological pharmaceutical composition containing axitinib HK1204564A1 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
PK40512 2012-06-25
PCT/EP2012/062365 WO2013000917A1 (en) 2011-06-28 2012-06-26 Topical ophthalmological pharmaceutical composition containing regorafenib
VE81612 2012-06-27
JOP20120170 2012-06-27
EP12198638 2012-12-20
PCT/US2013/044936 WO2013188273A1 (en) 2012-06-12 2013-06-10 Topical ophthalmological pharmaceutical composition containing axitinib

Publications (1)

Publication Number Publication Date
HK1204564A1 true HK1204564A1 (en) 2015-11-27

Family

ID=49758931

Family Applications (1)

Application Number Title Priority Date Filing Date
HK15105108.1A HK1204564A1 (en) 2012-06-25 2015-05-29 Topical ophthalmological pharmaceutical composition containing axitinib

Country Status (7)

Country Link
US (1) US20150164790A1 (xx)
EP (1) EP2863888A1 (xx)
JP (1) JP2015520230A (xx)
CN (1) CN104379133A (xx)
CA (1) CA2877715A1 (xx)
HK (1) HK1204564A1 (xx)
WO (1) WO2013188273A1 (xx)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013177367A2 (en) 2012-05-23 2013-11-28 The Johns Hopkins University Compounds and methods of use thereof for treating neurodegenerative disorders
KR101730399B1 (ko) 2015-04-13 2017-04-27 영남대학교 산학협력단 악시티닙을 포함하는 약물 전달체 및 이의 제조방법
CN108135737B (zh) 2015-06-06 2021-11-05 拨云生物医药科技(广州)有限公司 用于治疗翼状胬肉的组合物和方法
TWI700085B (zh) 2015-06-22 2020-08-01 新源生物科技股份有限公司 酪胺酸激酶抑制劑之眼用調配物的用途
EP3359258A4 (en) * 2015-10-07 2019-08-21 AiViva Biopharma, Inc. COMPOSITIONS AND METHOD FOR THE TREATMENT OF FIBROTIC SKIN DISEASES
KR20220080222A (ko) 2016-06-02 2022-06-14 에이디에스 테라퓨틱스 엘엘씨 비정상적 신생혈관이 있는 안구 질환 치료를 위한, 닌테다닙을 사용하는 조성물 및 방법
CN109157511A (zh) * 2018-09-10 2019-01-08 温州医科大学 一种眼表滴注抗新生血管类眼用制剂及其制备方法
US20220079980A1 (en) * 2018-09-27 2022-03-17 Novaliq Gmbh Lipid barrier repair
CN110974828B (zh) * 2019-12-24 2023-03-31 苏州大学 化合物Axitinib在制备治疗脑血管疾病的药物中的应用及其药物组合物
WO2021168218A1 (en) * 2020-02-19 2021-08-26 Clearside Biomedical, Inc. Compositions comprising axitinib and methods of treating ocular disorders
CN114533648A (zh) * 2020-11-26 2022-05-27 成都康弘药业集团股份有限公司 一种阿西替尼眼内植入剂
CN114685436B (zh) * 2020-12-25 2022-12-02 鲁南制药集团股份有限公司 阿昔替尼糖精共晶水合物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7141581B2 (en) * 1999-07-02 2006-11-28 Agouron Pharmaceuticals, Inc. Indazole compounds and pharmaceutical compositions for inhibiting protein kinases, and methods for their use
CA2760687A1 (en) * 2009-05-01 2010-11-04 Ophthotech Corporation Methods for treating or preventing ophthalmological diseases

Also Published As

Publication number Publication date
JP2015520230A (ja) 2015-07-16
CN104379133A (zh) 2015-02-25
CA2877715A1 (en) 2013-12-19
US20150164790A1 (en) 2015-06-18
WO2013188273A1 (en) 2013-12-19
WO2013188273A8 (en) 2014-02-13
EP2863888A1 (en) 2015-04-29

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